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Posts by Iyer Lab

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When AI replaces confidence in the classroom After students relied on AI for writing assignments, one molecular biology instructor reframed the issue as a confidence gap and implemented a collaborative assignment to foster scientific reasoning a...

My latest article was published today in ASBMB Today, where I explore how AI is reshaping student confidence and learning in the classroom.

www.asbmb.org/asbmb-today/...

2 hours ago 3 1 0 0

Sad to see that Don passed, he was a legend and a big part of why our community is so special. 🤯 20% of the collection?!!

1 week ago 4 1 0 0

Great to see this out. Practical guidance on how to use protein depletion systems in C. elegans

2 weeks ago 23 12 0 0

While the situation is grim at NIH, it's closer to catastrophic at NSF. They're just not able to move any money out the door. It appears OMB has them on lockdown. www.science.org/content/arti....

3 weeks ago 366 250 7 15

I am so very sorry for your loss 💔 My deepest condolences to you and your family…

4 weeks ago 1 0 0 0
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Recombinant monoclonal antibodies for labeling tubulin post-translational modifications in Caenorhabditis elegans #micropublication #biology #data #caltechlibrary #Celegans #Biochemistry #ExpressionDa micropublication.org/journals/biology/micropu...

4 weeks ago 1 1 0 0

Excited to see this out in the world. The CGC is launching a curated strains collection, the first being protein degradation systems and this is a pilot primer to pair with it authored by myself, Dave Reiner, Ann Rougvie, and Aric Daul. We review the state of the field and provide use guidance (1)

2 months ago 34 12 5 0
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📣 Please spread: we’re hiring a Lab Manager! It is a critical position in our new lab. As our lab moves to Barcelona and joins the @crg.eu, we’re looking for a Lab Manager to help build the lab and set the lab atmosphere.
🔗 Apply here 👉 recruitment.crg.eu/content/jobs...

2 months ago 90 94 2 3

Organelles do NOT have a single uniform pH.
And if you think they must, because “protons diffuse fast,” this paper is for you.
A thread on why that assumption is wrong; and what we found instead. 🧵 1/n

4 months ago 521 222 28 31
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MBoC Achieves Record Visibility in 2025: Over 3.49 Million Full-Text Views - ASCB Molecular Biology of the Cell (MBoC), ASCB’s flagship journal, reached a new milestone in 2025—surpassing 3.49 million full-text article views, the highest level of readership in the journal’s…

Molecular Biology of the Cell (MBoC) hit a new high in 2025 with 3.49M full-text views—the most in its history! Explore the top-read articles shaping cell biology today:

3 months ago 6 1 0 1
DYN-1 regulates SPD-2 and PLK-1 localization and mitotic spindle pole organization Accurate cytokinesis is essential for genome stability. Although dynamin is best known for its role in vesicular trafficking, its functions during mitosis remain unclear. Here, we identify a mitotic role for the C. elegans dynamin homolog DYN-1 in regulating spindle assembly and the localization of the key mitotic regulators SPD-2 and PLK-1. Depletion of DYN-1 results in enlarged metaphase spindle poles and increased centrosomal SPD-2 and PLK-1 levels. These effects likely depend on DYN-1's vesicular trafficking activity. Additionally, a subset of DYN-1-depleted embryos exhibit altered PLK-1 localization at the midbody during late mitosis, correlating with midbody assembly defects. Together, these findings establish DYN-1 as a previously unrecognized regulator of spindle pole organization and early midbody assembly. ### Competing Interest Statement The authors have declared no competing interest. National Institute of General Medical Sciences, 5P20GM103636-09, 7R15GM152965-02, 1R35GM153737 National Cancer Institute, 1R01CA273095

We are pleased to share with you our latest work showing that the endocytic protein dynamin regulates SPD-2 and PLK-1 levels during mitosis. Many thanks to the reviewers and the editor for their excellent feedback to improve the rigor and quality of our manuscript! www.biorxiv.org/content/10.1...

3 months ago 1 0 0 0
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Paul Maddox for Congress, NC-11 Paul Maddox, professor, entrepreneur, and world-renowned cancer researcher, is running for Congress because working families in Western North Carolina deserve a representative who cares for all our co...

My colleague Paul Maddox has paused his scientific career to run for Congress in NC's 11th District. Its the district where he grew up and where his mom and brother live. He saw how Hurricane Helene devastated the region and saw Trump's sad response 1/n
www.maddoxforcongress.com

3 months ago 27 4 1 0
Assistant Teaching Professor, Biology About the Opportunity About the Opportunity: We invite applications from qualified candidates for a full-time Non-Tenure-Track (NTT) Assistant Teaching Professor faculty position within the Department...

🚨My department is hiring a full-time Assistant Teaching Professor to teach undergrad Genetics & Genomics, upper-level Genomics, and an inquiry-based Computational Genomics course where students can do authentic research. 🧬💻

I’m on the search committee. DM me if you’re interested. Please share! 🙏

3 months ago 20 27 0 0
David's AlphaFold WorkShop 2026
David's AlphaFold WorkShop 2026 YouTube video by David Fay

Greetings! I decided to make a YouTube video of my AlphaFold workshop that I've given a few times in the past year. Caveats aside, people seem to find this useful for thinking about how to model protein interactions and how to interpret various AF outputs 1/2

www.youtube.com/watch?v=u63o...

3 months ago 102 32 2 1

If this accommodation is useful for your situation, PLEASE reach out to your POs. She specifically suggested that having some documentation from your PO may be useful to demonstrate eligibility for this accommodation.

4 months ago 11 8 2 1

She let me know that they recently received guidance that, ONLY for the January EI deadline (1/27/2026) and the February ESI deadline (2/3/2026), PIs can submit MIRAs even if their previous application (R35, R01, R15, R21, and R37) is still considered under review.

4 months ago 28 23 3 0

Hey all, I reached out to the PO of my NIGMS MIRA to ask if the gov't shut down, and rescheduling of study sections, might allow for some accommodation to the standard rule that PIs cannot resubmit a MIRA while their MIRA (or other RPG) is under review (waiting in scores or summary statements) 🧪

4 months ago 47 49 2 1
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Anyone @unlincoln.bsky.social in Lincoln, Nebraska

I’m speaking at the Johnny Carson center for the emerging media arts tomorrow night! Parents with kids are welcome!

Come hear about my career path and find out how important art is in science!
#nebraska #lincoln #science #art

5 months ago 12 4 0 0
Brandeis University, Biology Department Job #AJO30961, Assistant Professor in Biology and Neuroscience Program, Biology Department, Brandeis University, Waltham, Massachusetts, US

TT faculty job opening in #Neuroscience!
We are looking for a colleague to join us in our fantastic Biology Department and Neuroscience Program at Brandeis. We are a group of *very* collaborative, supportive, and productive scientists (& humans!) so please apply
academicjobsonline.org/ajo/jobs/30961

5 months ago 86 102 1 3
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Epitope tag antibody collection Epitope tags are short amino acid sequences fused to a protein’s N- or C-terminus. When paired with an antibody that specifically recognizes this sequence, epit

Frequent user of epitope tags? Try ours!

IPI epitope tag antibodies & plasmids are now available through our partner @addgene.bsky.social!

buff.ly/YEuZDIp

6 months ago 25 10 0 2
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#labdaptations for inclusive laboratory research Nature Reviews Chemistry - Disabled scientists encounter many barriers in laboratory spaces, especially a lack of accessible lab equipment. #labdaptations is an ever-growing database of inclusive...

Inclusive lab adaptations for scientists who need them

6 months ago 4 2 0 0
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MacKenzie Scott gives $70 million to UNCF to financially strengthen HBCUs Billionaire philanthropist MacKenzie Scott has donated $70 million to the UNCF, the largest private provider of scholarships to minority students.

apnews.com/article/mack... Scott gives $70 million to UNCF to financially strengthen HBCUs

6 months ago 35 16 0 0
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Foliar mRNA spray induces protein synthesis in monocot crop and dicot model plant species In planta gene expression via exogenous mRNAs has a wide range of potential biotechnological applications from genome editing to plant protection and to circumventing tissue culture. Yet, regarding mR...

😮 Just WOW!!

Spray GFP mRNAs on plant leaves and the leaves translate this and you get glowing leaves.

www.biorxiv.org/content/10.1...

8 months ago 51 12 2 5

Dynamin regulates PLK-1 localization and spindle pole assembly during mitosis www.biorxiv.org/content/10.1101/2025.07....

9 months ago 1 1 0 0

Double Congratulations!

8 months ago 1 0 0 0

I’m pleased to share the latest preprint from the Iyer Lab! 🎉
We uncover a novel role for dynamin in regulating spindle pole assembly and PLK-1 localization during late mitosis in C. elegans embryos.
Read it here 👉 www.biorxiv.org/cgi/content/...
#CellBiology #C_elegans #Cytokinesis
#Dynamin #PLK1

9 months ago 19 2 0 0
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The midbody and midbody remnant: from cellular debris to signaling organelle with diagnostic and therapeutic potential | Molecular Biology of the Cell The midbody (MB), a transient structure formed during cytokinesis, has evolved from a mere structural component to a complex signaling organelle with diverse functions beyond cell division. Recent stu...

Our review is out! Such an honor to publish with Ryoko and Michael-early midbody leaders!

The midbody and midbody remnant: from cellular debris to signaling organelle with diagnostic and therapeutic potential

www.molbiolcell.org/doi/full/10....

9 months ago 12 2 0 1
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Nobel winners of worms! Curiosity driven science is essential! @genetics-gsa.bsky.social

9 months ago 13 3 0 1
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Hey @socdevbio.bsky.social Hope you all can make my plenary talk this Thursday am in sunny 😎 San Juan! Will be speaking about MBRs—translating large EVs generated in mitosis!

10 months ago 3 2 0 0
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Rapid Response Bridge Funding Program In the face of recent abrupt shifts in federal funding for education research, including large-scale terminations of National Science Foundation (NSF) research grant awards, we have developed a rap...

Very smart, high ROI initiative from the Spencer Foundation.

Providing bridge funding for canceled NSF grants:

1) directs funds to projects already screened by a top-noch review process.
2) avoids imposing proposal prep costs on researchers.
3) ameliorates the disruption from GOP sabotage.

10 months ago 776 334 6 10