🔬 Antibody of the Week: AbFlex® PLK1 antibody (rAb)
Meet our AbFlex® PLK1 antibody, part of our AbFlex recombinant antibody (rAb) collection [https://bit.ly/3JHsQFo]

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#AntibodyOfTheWeek #Epigenetics #ActiveMotif #AbFlex #PLK1 #RecombinantAntibody #Research #MolecularBiology

Polo-like kinase 1 maintains transcription and chromosomal accessibility during mitosis | Molecular Biology of the Cell Transcription persists at low levels in mitotic cells and plays essential roles in mitotic fidelity and chromosomal dynamics. However, the detailed regulatory network of mitotic transcription remains ...

New from the Burkard Lab: Polo-like kinase 1 maintains transcription & chromosomal accessibility during mitosis.We show PLK1 is vital not just for mitotic machinery but for keeping promoter/TSS regions accessible & transcription active. Check it out www.molbiolcell.org/doi/10.1091/... #mitosis #plk1

I’m pleased to share the latest preprint from the Iyer Lab! 🎉
We uncover a novel role for dynamin in regulating spindle pole assembly and PLK-1 localization during late mitosis in C. elegans embryos.
Read it here 👉 www.biorxiv.org/cgi/content/...
#CellBiology #C_elegans #Cytokinesis
#Dynamin #PLK1

A pleasure contributing to #ESMORareCancers25 with a talk about #adrenocorticalcarcinoma. Well done Alessandra Mangone presenting our #ENSAT study on predictors of treatment response & Emanuela Esposito for poster on #PLK1 inhibitors 👏 👏 #MedSky #EndoSky @unibirmingham.bsky.social
ow.ly/yNk150Vm4hC

How exactly does #PLK1 function in prophase?
Peter Lenart @plenart.bsky.social and coworkers find its inhibition to delay #CDK1 activation and mitotic entry, inducing a prolonged and phenotypically variable prophase-like state
www.embopress.org/doi/full/10....