Thrilled to be starting my postdoc @unibirmingham.bsky.social.
Working with @bucknerlab.bsky.social to explore how biofilm growth influences the evolution of plasmid-mediated AMR and hyper-virulence in Klebsiella pneumoniae. Big questions, exciting times.
#AMR #Biofilms #plasmids #microsky

Trade-offs between phage resistance and conjugative ability shape the ecological and evolutionary response of a multidrug resistance plasmid to plasmid-dependent phage Phage therapy is a promising alternative to antibiotics to treat multidrug resistant infections. Plasmid dependent phages (PDPs) are particularly attractive as therapeutics because they can both kill ...

New pre-print www.biorxiv.org/content/10.1...
Plasmid-dependent phage (PDPs) are ubiquitous, but the selective pressures that they impose on plasmids are not well understood. Project led by Daniel Cazares in collaboration with @brockhurstlab.bsky.social!
#phagesky#microsky

🚨 Call for Abstracts! 🚨
Exeter Microbial Genomics Early Careers Symposium 🦠🧬

Present your work, chair a session, win prizes & network!
📅 12 Nov
📍 Penryn Campus
⏰ Submit TODAY by 5pm 👉 linktr.ee/microbesng

#MicrobialGenomics #ECR #MNGPopUp
Organised with @drramabht.bsky.social @exeter.ac.uk

CRISPR system reprograms bacteria to disarm deadly toxin Gene-editing technique disables Shiga toxin genes in <i>E. coli</i>

Scientists have developed a new gene-editing approach that reprograms pathogens to stop producing toxins and instead make a helpful molecule. cen.acs.org/biological-c...

#CRISPR #geneediting #MolecularBiology #MolBiol #microsky

very stimulating blog post for all those who are interested in phylogenetic trees and their construction (without being experts themselves) 👇 great weekend read!
thx andrew @andrewjroger.bsky.social for pointing this out🙏
#MicroSky

Biofilms 11

📢 The full #Biofilms11 programme is now available and is packed with groundbreaking content that will spark collaboration and inspire new ideas💡

🗓️ Join @ukbiofilms.bsky.social and @microbiologysociety.org from 13-15 May 2025 in Cardiff ➡️ tinyurl.com/2karbnht

#biofilms #biofilm #MicroSky

We also have a couple of poster presentations today 255 from @drramabht.bsky.social, 282 from @anna-k-richmond.bsky.social, 062 from Meg Llewellyn and 068 from Jasmine Thomas-Campbell. All cool stuff about defence systems!

At Poster 092 today! Loss of quorum sensing and a promoter region mutation in lung-like environments

@brockhurstlab.bsky.social giving a talk about eco-evolutionary mechanisms of AMR in the AMR session at #Microbio25

Poster A097 tomorrow at #Microbio25!

Research Fellow - Department of Microbes, Infection and Microbiomes - 104952 - Grade 7 To take a lead role in the development and delivery of an MRC funded UK-China research network on antimicrobial resistance epidemiology

A reminder that there just a few days left to apply to work with us as a post doc on DETECTIVE-II. MRC funded project to work on genomics and metagenomics of AMR in China and the UK

edzz.fa.em3.oraclecloud.com/hcmUI/Candid...

glad to be here!

This is a truly incredible resource for anyone working on bacterial genomics. I'm struggling to assemble and organise 1,000 bacterial genomes, and I can’t even begin to fathom handling 2.4 million 🤯

PhD studentship alert!! Two projects available with me fully funded by BBSRC

This one is a collaboration with Dr Michelle Buckner
warwick.ac.uk/fac/cross_fa...

And this one a collaboration with @overtonlab.bsky.social warwick.ac.uk/fac/cross_fa...

Both will be lots of fun! Come & join us 😃

Incredible graphic - the myriad of ways that bacteria defend themselves against antibiotics.

14 resistance mechanisms, summarised by Idan Yelin & Roy Kishony in Cell

www.sciencedirect.com/science/arti...

Thank you!

Me too :)

💊GW4 AMR Alliance Newsletter - October 2024 For more details, read the full article by clicking the link below.

Happy to be featured in the GW4Alliance Newsletter this month!

us6.campaign-archive.com?u=bfba6544e4...

Research Assistant - Impact Of Microbe-Pathogen Interactions On The Health Of Individuals With Cystic Fibrosis:Oxford Road

🚨 The Whelan lab is hiring! 🚨 We're looking for a Research Assistant to join our lab at U of Manchester. We're seeking someone with experience in microbiology & microbiome to support our growing group. Note this isn't a postdoc role (though keep 👀 for those announcements soon!) #Microsky 🧪 🧬 💻

Are you a researcher with an interest in #microbiology, #ecology and #evolution? Join our upcoming scientific discussion meeting on the topic of microbial immune systems: ow.ly/fcKR50S89xA

How do interactions in the microbiome shape the evolution of antibiotic resistance in bacterial pathogens? at Queen’s University Belfast on FindAPhD.com PhD Project - How do interactions in the microbiome shape the evolution of antibiotic resistance in bacterial pathogens? at Queen’s University Belfast, listed on FindAPhD.com

Please share: Funded PhD project on the ecology and evolution of antibiotic resistance 🦠🧬🫁 at Queen’s University Belfast.
Application deadline: 21 June
Please 📧 me with any questions, happy to chat!

www.findaphd.com/phds/project...

Wohoo 🎉 🎉Many Congratulations James!!!

SMBE pangenomes meeting details
Dates: 26-28th November 2024.
Location: National Museum of Nature and Science, Ueno Park, Tokyo, Japan.
Abstract submission: 1st June-31st August.
Registration: 1st July-31st October.
See the updated website: smbepangenomes.bacpop.org

Ecological and evolutionary mechanisms driving within-patient emergence of antimicrobial resistance - Nature Reviews Microbiology In this Review, Shepherd, Brockhurst and colleagues explore the clinical evidence in support of four major ecological and evolutionary mechanisms of within-patient antimicrobial resistance emergence i...

Thrilled to share our new article now out in Nature Reviews Microbiology! We review how bacterial #AMR evolves within patients during #antibiotic therapy, highlighting the complexity of the problem and how to improve understanding in future work. 1/7 #MicroSky
www.nature.com/articles/s41...

Awesome 👏👏👏 Congratulations Matt!!!

All set for the Pangenomics course by @jomcinerney.bsky.social @physaliacourses.bsky.social
Excited and looking forward to learning a lot from the expert himself!!!

Congratulations Mike!!

Using phage therapy to resensitize P aeruginosa to antibiotics in murine lung infection, featuring @mermanchester.bsky.social’s Rosanna Wright, led by Jo Fothergill www.nature.com/articles/s41...

Excited to share that our official website is now live 🎉🎉 Find out more about our team and our exciting research here sites.exeter.ac.uk/multidefence/

Congratulations Matt!!! Wish I could be there to celebrate your success. Hopefully will see you soon :)