Kupffer cell programming by maternal obesity triggers fatty liver disease Nature - In a mouse model, maternal obesity during pregnancy can lead to fatty liver disease in the offspring, driven by aberrant developmental programming of Kuppfer cells.

We are SO EXCITED to share our story @nature.com:
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Maternal obesity reprograms fetal liver macrophages, triggering adult fatty liver disease in the offspring.
This study uncovers how Kupffer cells act as intergenerational messengers in metabolic disease.
👉 Read here: rdcu.be/erD3b

Frontiers | Developmental programming of tissue-resident macrophages

Is #niche alone really everything? We discuss the concept of #developmental_programming & how #macrophage #ontogeny #longevity #environment can influence #macrophage functions later in life
www.frontiersin.org/journals/imm...

Happy to be here at 🦋 ! looking forward to seeing beautiful posts about #macrophages #immunology #microglia #hematopoiesis and much more...

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