New in #SubtiWiki: Clusters of structural homologs!
Enjoy the new feature!
Thank you, Oskar Geissel & @c-elfmann.bsky.social
@uni-goettingen.de @imprsgs.bsky.social

Yesterday, we had the graduation ceremony and PhD party of @c-elfmann.bsky.social .
@uni-goettingen.de @imprsgs.bsky.social #SubtiWiki

Today @c-elfmann.bsky.social , the mastermind of #SubtiWiki successfully defended his PhD thesis! The 50. PhD graduate from the group! Congratulations, Christoph!
@uni-goettingen.de @imprsgs.bsky.social

Sneak preview of the next upcoming #SubtiWiki feature: All proteins are assigned to clusters sharing similar structures!
Brought to you by Oskar Geissel and @c-elfmann.bsky.social .
@imprsgs.bsky.social

Thank you! 🙏

For what it's worth, it's now supported (since a couple of months ago)!

I'm participating the ISMB/ECCB 2025 conference, join me! Register now

I'm presenting #ISMBECCB2025 in Liverpool, United Kingdom from July 20-24. Who else is going? Register here and don't miss it! invt.io/1bxb9bltizy

Some of our servers are currently having issues with their HTTPS certificates. Please use HTTP URLs like subtiwiki.uni-goettingen.de and pae-viewer.uni-goettingen.de as a workaround for now!

Screenshot of a gene page on SubtiWiki showcasing the new BlueSky feed in the sidebar.

We now have a #BlueSky hashtag feed on SubtiWiki!

Just add the hashtag #subtiwiki to your post and it will appear in the sidebar of gene / metabolite pages!

Finally fixed some issues with PTMs for the PAE Viewer! Instead of the per-atom PAE which #AlphaFold outputs for modified amino acids, the average per-residue PAE is now displayed. subtiwiki.uni-goettingen.de/v4/paeViewer...

@imprsgs.bsky.social @unigoettingen.bsky.social

And of course many thanks to Cameron Gilchrist and Woosub Kim for their work on the search server and on Foldseek-Multimer, respectively, which was used in our implementation!

Thanks a lot to Michel van Kempen, Stephanie Kim, Charlotte Tumescheit, the Soeding Lab, @martinsteinegger.bsky.social for the development of Foldseek! Also check out the fantastic search.foldseek.com by @milot.bsky.social, which we used as a blueprint. It boosts more options and better evaluation!

A screenshot of the results table of a Foldseek search on SubtiWiki. It shows multiple entries and corresponding metrics. One of the rows is expanded, revealing a 3D visualization of a superimposition of the target and the query structure corresponding to the search hit.

Try out our integration of the amazing protein structure search tool #Foldseek on #SubtiWiki (subtiwiki.uni-goettingen.de/foldseek)! Just upload a structure or use PDB/AlphaFoldDB entries to find similar structures. #IMPRS-GS #UniGoettingen
#alphafold #bacillus #subtilis