The worst cancers with respect to lethality get the least federal funding support
jamanetwork.com/journals/jam...

I've started a list of people working on #cancer #evolution. Many more to be added, so do let me know if that is you. Also if you would like to be removed. go.bsky.app/QuAF4Mo

🔬IGMM (CNRS/ Univ Montpellier) is hiring Group Leaders in Innovative Biology. @cnrsbiologie.bsky.social @cnrs.fr @umontpellier.bsky.social
📅 1 May–15 June 2026
📩 search2026@igmm.cnrs.fr
📎Full information 👇
#LifeScience #MolecularBiology #Research #PI #CNRS

Cancer neuroscience: The past, the present, and the road ahead Both the nervous system and cancer-intrinsic neural features can govern cancer initiation, growth, progression, metastasis, and treatment resistance, …

What are the current and emerging topics in Cancer Neuroscience, and what comes next for the field?

In our new review, now online @cp-cell.bsky.social, we discuss previous and ongoing research from leading laboratories and propose future directions for research. 🧠🔬

Curious? See link below 😀👇

Welcome back to #moleratmonday, your place to learn everything there is to know about naked mole rats 🐀 Today’s fact:

Naked mole rats are poikilothermic, meaning their body temperature fluctuates considerably with the ambient temp, rendering them effectively cold-blooded 🌡️🩸

Life Science Research Professional 1 in School of Medicine, Stanford, California, United States Stanford University is seeking a Life Science Research Professional 1 to study the mechanisms of aging and rejuvenation, particularly in a variety of....

Interested in aging and rejuvenation?

We have a new Research Assistant position to understand aging at the cellular level!!

Come join our team!!! 😎

careersearch.stanford.edu/jobs/life-sc...

✨Registration is OPEN for the 2026 FASEB on Epigenetics in Aging and Disease in Malahide, Ireland!✨
Featuring @denadubal.bsky.social and Yang Shi from @ludwigcancer.bsky.social as Keynotes. Speaker slots available!

With: @bbparis1984.bsky.social Ashby Morrison, Ernesto Guccione

Naked Mole-rat Cam Watch the Naked Mole-Rat Cam for an inside look at how these unusual rodents spend their lives.

It’s Monday, so it’s time for #moleratmonday 🐀 Today’s fact:

Watch them live! 📹 The Smithsonian National Zoo has two live webcams featuring their naked mole rat enclosure. Check them out:

nationalzoo.si.edu/webcams/nake...
#nakedmolerat

Cancer cell plasticity is viewed as a driver of therapy resistance. Here, we propose the concept of “Field-Oriented” Therapy—leveraging plasticity rather than merely enduring it. To learn more, read: aacrjournals.org/cancerdiscov...

Immune cell ‘bloodhounds’ track cancer cells’ unique metabolic signatures, eliminate tumors in mice Immune cells engineered to sense metabolic byproducts secreted by cancer cells ‘follow their noses’ to migrate to and infiltrate solid tumors in mice in a Stanford Medicine study.

Young-Min Kim, in the lab of Livnat Jerby, in collaboration with Fabrizia Urbinati in the IMA has engineered immune cells to act as cellular ‘bloodhounds’, tracking the metabolic byproducts of cancer cells to better infiltrate and destroy solid tumors:

I have so many words about this.
And I think its effects could be bigger than they seem on the surface.

Grateful to all collaborators, trainees (especially first author Jun Kim), and funding agencies who made this work possible

Combining cysteine depletion with cisplatin or venetoclax leads to stronger tumor control than either treatment alone in SCLC models, pointing to a translational path for exploiting this metabolic weakness.

ASCL1-high SCLC cells are resistant to ferroptosis induced by cysteine depletion and instead die from apoptosis, in large part because ASCL1 (and not NEUROD1) directly regulates the expression of GCH1, which leads to high levels of the BH4 antioxidant. Cool observations made by Christina Bebber!

All the SCLC cell states we tested depend on exogenous cysteine because none these SCLC cells express GNMT, which is critical to making homocysteine (and then cysteine, and then glutathione) from methionine.

New preprint from the lab! Close collaboration with Silvia von Karstedt @vonkarstedtlab.bsky.social and her lab. We find that #SCLC cells are strikingly dependent on exogenous cysteine #LungCancer #CancerMetabolism #Ferroptosis 🧵
biorxiv.org/content/10.64898/2026.03.27.714827v1

Nicolas Altemose, assistant professor of genetics at Stanford Medicine

"Some of the most important future scientific discoveries are currently hidden in unexpected places. That's why we're following our curiosity to explore the dark corners of the genome."

Stanford Medicine magazine: The power of research

Spotlight on Nicholas Altemose, assistant professor of genetics: The Altemose Lab applies new tools and technologies to explore the biology of repetitive areas of the human genome. stanmed.stanford.edu/repetitive-d...

Frontiers | A feedback loop between cell proliferation and ROS regulates ferroptosis sensitivity BackgroundFerroptosis is a form of regulated cell death characterized by iron-dependent lipid peroxidation and membrane rupture. While cellular populations r...

Ever wondered how cellular #metabolism, #ROS, cellular confluence and #Ferroptosis are connected? Read our new study with theoretical physicist Johannes Berg @unicologne.bsky.social @cecad.bsky.social @uniklinikkoeln.bsky.social @dtg-cologne.bsky.social
www.frontiersin.org/journals/cel...

We're back with Day 2 of #MarkSymposium! Our first session, on novel cancer therapies, featured a powerhouse lineup including William Sellers, @amanglik.bsky.social, and @juliensage.bsky.social. The future of targeted treatment is bright. ⚡️ #CancerTherapy

Once again, it’s #moleratmonday, where we provide a naked mole rat fact every Monday 🐀 Today’s fact:

Their scientific name is Heterocephalus glaber, which means “different-headed” and “hairless”, a pretty on-the-nose description!

#nakedmolerat

Le retour mercredi promet

Michael Bishop, Nobel Prize in Physiology or Medicine 1989: Official Lecture YouTube video by Nobel Prize

Very sad to hear of the passing today of our UCSF colleague Mike Bishop at the age of 90. A legendary and inspiring figure. He also led UCSF as Chancellor. Have a listen to his Nobel lecture. youtube.com/watch?v=CDv7...

We are seeking a highly motivated scientist with expertise in mouse embryo manipulation and the generation of genetically engineered mouse models. This is a permanent position with competitive compensation. Contact me via direct message if interested. Please share!

Ravi Nath and Claire Bedbrook stand in an aisle of shelves filled with fish tanks. Photo by Andrew Brodhead.

On today's podcast, we talk with neuroscientists Claire Bedbrook and Ravi Nath about their new study, which found that an animal's lifespan can be predicted surprisingly early by observing its behavior. @brunetlab.bsky.social @deisseroth.bsky.social

🔗 neuroscience.stanford.edu/news/why-do-...

Walk With Me: Steven Artandi, oncologist studying cancer biology and aging YouTube video by Stanford Medicine

Meet Steven Artandi, a physician-scientist who studies cancer biology. His work helps uncover the mechanisms that enable cancer to grow and persist. Learn what he wanted to be when he was a kid — and the quote he lives by. youtu.be/UWwT5owtCdc?...

@stanford-cancer.bsky.social

It’s #moleratmonday, where we bring you a fun fact about the naked mole rat, every Monday 🐀 Last week we mentioned their long lifespans, but saved the best part for this week:

The current record for the oldest naked mole rat is 40 years old! It lived in the care of the Rochelle Buffenstein lab ❤️

Register to the Biological Methylation meeting!
June 15-18 in Dublin
Many award opportunities for trainees (see the award page)
Several talks selected from abstracts (deadline Apr 20)
Come listen to and share awesome science, meet colleagues and make new connections!
events.faseb.org/event/biolog...

We are hiring!

Multi-tissue transcriptomic aging atlas reveals predictive aging biomarkers in the killifish - Nature Aging Characterizing molecular aging features is crucial for understanding systemic and local factors contributing to the aging process. Here Costa, Chen et al. performed RNA sequencing on 13 tissues across...

Multi-organ transcriptomic aging atlas in killifish, with both males and females! 🐟🐟🐟

Huge congratulations to Emma, Jing, Tony and the entire team!! ✨⭐

@emkcosta.bsky.social
@jingxunchen.bsky.social
Wyss-Coray lab!

www.nature.com/articles/s43...

Targeting immune cells in the aged brain reveals that engineered cytokine IL-10 enhances neurogenesis and improves cognition Immune cells populate the old brain, but whether they can be specifically targeted to improve brain function in older individuals remains unclear. Navarro Negredo et al. dissect how aging impacts brai...

Excited to share our new study using engineered immune proteins to quench inflammation in aged brains!!

Congratulations to Paloma Navarro and the entire team!

Fantastic collaboration with Chris Garcia's lab, Tony Wyss-Coray's lab, and Saul Villeda's lab!

www.cell.com/immunity/ful...