Cut&Shut

PhD opportunity at LMU Munich 🇩🇪
Join our lab to study the molecular and cellular biology of Apicomplexan parasites, with a focus on the apical complex, motility regulation, and post-translational modifications.
Apply: elena.jimenez@lmu.de
job-portal.lmu.de/jobposting/6...

UZH: Postdoc The newly founded Cryptosporidium lab at the Institute of Parasitology focuses on the genetic and transcriptomic basis of parasite virulence and persistence in Cryptosporidium and is committed to incl...

🚨 Postdoc position 🚨
I’m moving back to Switzerland this summer to launch my lab at the University of Zurich and am recruiting a Postdoctoral Fellow (start: late 2026).
Details & application:
jobs.uzh.ch/job-vacancie....

Please share! 😊

Cartoon representing the mycobacterial oxidative phosphorylation system, including cytochromes, NDH-2, and ATP synthase. Taken from Figure 1 of the article.

#Microbiology

The anti-tuberculosis drug bedaquiline targets the mycobacterial ATP synthase, but how that leads to bacterial death is unclear

Here the authors clarify how bedaquiline works

@jnblab.bsky.social @morwan.me
#TBSky #antibiotics #AMR

http://dlvr.it/TQjZ0W

I am pleased to share our latest preprint, detailing the characterisation of BDF7 in Leishmania. This non-canonical bromodomain factor is essential for the parasite to live inside the host macrophage and has a parasite specific function compared to the host ortholog , ATAD2. Details in the link:

🦠 Grad students & postdocs in parasitology:
Apply now for the Biology of Parasitism (BoP): Modern Approaches course at @MBLScience.
Hands-on labs, expert lectures, and cutting-edge tools.
📅 Summer 2026 | ⏰ Deadline Feb 5
🔗 mbl.edu/courses

chris hill PhD Projects, Programmes & Scholarships - 3 PhDs Listed FindAPhD. Search Funded PhD Projects, Programmes & Scholarships in chris hill. Search for PhD funding, scholarships & studentships in the UK, Europe and around the world.

🚨Attention prospective PhD students🚨
Are you interested in molecular mechanisms, RNA viruses, structural biology or biophysics? 🧬🦠🧪

We have THREE fully-funded PhD projects available for October 2026 entry:
www.findaphd.com/phds/?Keywor...

Please share/repost, and get in touch if you're interested

We have an open post-doc position in my group to study mRNA cleavage and polyadenylation using biochemical reconstitution and cryoEM.

Please get in touch if you are interested in joining this amazing team! 🔬🧬🤩
#RNA #cryoEM

[We are Hiring!]

The Weiss Lab at Albert Einstein College of Medicine (NY) is hiring a Postdoc Scientist to explore the Toxoplasma gondii cyst wall using XL-MS, Split TurboID, & U-ExM.

This project aims to unlock new strategies for treating toxoplasmosis.

DM for more info!

📣 Open postdoc position in my lab to investigate how Toxoplasma acquires nutrients. Join me at the University of Edinburgh. Closing date 14th August. More details below ⬇️

elxw.fa.em3.oraclecloud.com/hcmUI/Candid...

The fast-evolving FIKK kinase family of Plasmodium falciparum can be inhibited by a single compound - Nature Microbiology FIKK effector kinases underwent rapid evolutionary expansion and are a druggable target in Plasmodium falciparum.

Better late than never, but I am thrilled to share our newest research from the Treeck lab!!! www.nature.com/articles/s41...

Specialised RNA decay fine-tunes monogenic antigen expression in African trypanosomes Antigenic variation is a sophisticated immune evasion strategy employed by many pathogens. Trypanosoma brucei expresses a single Variant-Surface-Glycoprotein (VSG) from a large genetic repertoire, whi...

So happy to share the first preprint from our lab on post-transcriptional regulation at the VSG expression-site body in trypanosomes. @ybri-uoy.bsky.social @york.ac.uk

Defining the chromatin-associated protein landscapes on Trypanosoma brucei repetitive elements using synthetic TALE proteins Kinetoplastids, such as Trypansoma brucei, are eukaryotes that likely separated from the main lineage at an exceptionally early point in evolution. Consequently, many aspects of kinetoplastid biology ...

Our latest collaborative work with Keith Matthews’ lab using synthetic DNA binding proteins to explore the chromatin protein contexts of repetitive sequences in Trypanosoma brucei in now on bioRxiv - thanks to all involved! 2025.04.22.649942; doi: doi.org/10.1101/2025...

We have a 3-year PDRA post in Cancer Immunogenomics. Ideal to use and strengthen your bioinformatics skills to discover how cancer transcriptome quirks shape immunotherapy outcomes. Funded by @cancerresearchuk.org. It’ll be fun!
jobs.york.ac.uk/vacancy/rese...
@hyms.ac.uk
@ybri-uoy.bsky.social

Keep VEuPathDB open-access to all by subscribing today! veupathdb.org/veupathdb/ap...

Anopheles mosquito survival and pharmacokinetic modeling show the mosquitocidal activity of nitisinone Nitisinone reduces survival of the malaria-transmitting mosquito Anopheles gambiae by blocking tyrosine catabolism.

Glad this is finally out. Using pharmacokinetic modeling we show that #nitisinone, an FDA-approved drug 4 #Tyrosinemia & #Alkaptonuria, kills #Anopheles mosquitoes, outperforming #Ivermectin. Grateful to all primary author’s & fantastic collaborators!

www.science.org/doi/10.1126/...

Structure and Activity of the Essential UCH Family Deubiquitinase DUB16 from Leishmania donovani In Leishmania parasites, as for their hosts, the ubiquitin proteasome system is important for cell viability. As part of a systematic gene deletion study, it was discovered that four cysteine protease...

New preprint: results from a collaborative project funded by the GCRF Global Network for NTDs investigating Leishmania deubiquitinase 16 as a potential drug target. @ybri-uoy.bsky.social @mottramlab.bsky.social www.biorxiv.org/content/10.1...

🥁🥁 Job alertttt!! Interested in weird biology of malaria parasites? Inducible genetic screens? Single-cell RNAseq? Come postdoc with us - www.parafugelab.com ! International applicants or applicants just finishing up their PhD, both welcome!!

www.jobs.gla.ac.uk/job/research...

Is there a way to download all of NIH Bioart (in case it is taken offline by the current regime in the USA)?

bioart.niaid.nih.gov/discover

MRC- funded PhD project at the interface between biology & physics to investigate the segregation of an antibiotic resistant plasmid. Interdisciplinary training with super supportive supervisors.

In the beautiful historic city of York.

Please re-post, thanks! #microsky
🦠🧫🧪
📆17 December

Happy to see this now online at ACS Infectious Diseases . Catherine & the team did a great job on the initial structural & biophysical assessment of BDF5 bromodomains as potential drug targets in Leishmania. #parasite #epigenetics

t.co/UoI9i1NSux

Hello Bluesky