This work started @edinuni-irr.bsky.social and continues @uofgsii.bsky.social after our relocation in 2025. Most experiments performed across institutions and the @crick.ac.uk to ensure reproducibility. Thanks to all involved. Full post once published 📖
Our latest preprint in an awesome collaboration with the Wack Lab @crick.ac.uk. Led by @chrysante-ili.bsky.social, @woutertj.bsky.social and @isobelmouat.bsky.social.
We show that monocytes follow a largely conserved differentiation blueprint in the 🫁 when elicited by distinct challenges.
“I think it’s a real mistake to forget where the pipeline for all this begins.”
John Diffley reflects on the importance of basic research, his mission to decode DNA replication and recreate it in the lab, and the scientific optimism of the 1960s that helped shape it.
www.crick.ac.uk/news/2026-03...
Lovely to see the imaging by @lizihegarty.bsky.social making the front cover of @mucosalimmunol.bsky.social. Instead is our work on #macrophage heterogeneity & dynamics in health & inflammation. We also did a short podcast to discuss the main findings. @edinuni-irr.bsky.social @uofgsii.bsky.social
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Our Career Enhancing Grant supports training like this. Applications close 25 March.
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Our latest preprint, led by @lizihegarty.bsky.social & aided by @erinwatson.bsky.social shows that fixation time matters when it comes to visualising #macrophages in #salivarygland & other epithelia.We find 1hr allows detection of mac subsets while preserving architecture. With @bainlab.bsky.social
Fixation matters: duration in fixative prior to immunofluorescent analysis directly impacts macrophage visualisation in epithelial tissues www.biorxiv.org/content/10.64898/2026.02...
⌛Time is running out!
Abstract submission closes tomorrow. Don't miss your chance to present your work at #SIGNET26
Join the Scottish immunology community in Perth to network, share the latest findings and explore new breakthroughs
🔗 Find out more https://bit.ly/49VL6FA
This #MucosalMonday @bainlab.bsky.social and @lizihegarty.bsky.social are in the Authors Corner discussing their recent #macrophage work from MI. Then @kknoop.bsky.social brings you more allergy and anaphylaxis with Caroline Sokol and @stephanieeisen.bsky.social:
www.iheart.com/podcast/269-...
Very nice commentary of @lizihegarty.bsky.social’s recent paper in @mucosalimmunol.bsky.social by Florent Ginhoux and colleagues #macrophage #colon @bainlab.bsky.social
Thanks to Peiliang Cai, Zhaoyuan Liu and @florentginhoux.bsky.social for their great Commentary on our recent study led by @lizihegarty.bsky.social proposing a framework for defining murine colonic macrophages @mucosalimmunol.bsky.social
@edinuni-irr.bsky.social
@uofgsii.bsky.social
Merry Christmas to all colleagues, collaborators and friends. I hope everyone has a good break and some rest. See you in 2026!
Key points on the need for continued animal use in scientific research. www.theguardian.com/science/2025...
Thanks for sharing @mucosalimmunol.bsky.social. This work was led by @lizihegarty.bsky.social during her PhD @edinuni-irr.bsky.social funded by @wellcometrust.bsky.social. Now being continued after our relocation to @uofgsii.bsky.social.
Might be of interest to @emds2025.bsky.social attendees!
A big thanks to Lizi for her hard work - started in the midst of the pandemic. Thanks to all collaborators who helped make this work possible, to the reviewers and to the editorial team at Mucosal Immunology for the efficient process.
Do tissue resident #macrophages survive through intestinal #inflammation? Are they terminally differentiated or can they adapt? @lizihegarty.bsky.social asked these Qs during her @wellcometrust.bsky.social PhD and her findings are now published @mucosalimmunol.bsky.social
@edinuni-irr.bsky.social
#Neutrophils are short lived cells, yet in ARDS display long term changes, with impaired neutrophil functions even after 6 months. How can they undergo long term reprogramming?
this is what @mas-g.bsky.social answered, mapping changes to neut. progenitors. @walmsley-lab.bsky.social #immunosky
Calum Bain stood on the majestic McEwan Hall stage in front of a podium below a large screen introducing the meeting and welcoming delegates
Mariola Kurowska-Stolarska stood on stage below a large screen presenting recent findings on dendritic cell heterogeneity in rheumatoid arthritis.
Gareth-Rhys Jones stood on stage below a large screen discussing the role of monocyte-derived activin in intestinal repair.
Ed Roberts stood on stage, with the camera straight on, discussing decoding the roles of migratory and resident dendritic cells in protective immune responses
🆕 | @uofgsii.bsky.social researchers played a key role in delivering the 38th EMDS meeting, held 16–18 Sep in Edinburgh.
Led by @bainlab.bsky.social and @mariolaks.bsky.social with colleagues at @edinburghuni.bsky.social, the event hosted over 260 delegates.
🔗 More: www.gla.ac.uk/schools/infe...
Did you attend #EMDS2025? If so, please take time to tell us about your experience in the survey you received. This will help the organisers of #EMDS2026 (Amsterdam, November 2026)
@edinuni-irr.bsky.social
@britsocimm.bsky.social
Well done @lizihegarty.bsky.social. You are an exemplar postdoc - hardworking, well-read, conscientious, supportive, collegiate, all while being good fun (and expert in where to dine!!). Delighted to have you as a colleague.
@edinuni-irr.bsky.social
@uofgsii.bsky.social
@britsocimm.bsky.social
Great to see this out for all to see after a lot of hard work by @lizihegarty.bsky.social and @bainlab.bsky.social. Colonic #macrophages persist but are transcriptionally altered post- #inflammation in a mouse model of #colitis.
Delighted all of @lizihegarty.bsky.social's hard work as paid off. She shows that tissue resident colonic #macrophages persist through #inflammation and adapt to aid tissue repair.
Lovely collaborative work with colleagues @edinuni-irr.bsky.social and beyond. 🙏🏻
@uofgsii.bsky.social
Amazing! Well done @lizihegarty.bsky.social. Thoroughly deserved. You contribute so much to the Emmerson and Bain labs.
@edinuni-irr.bsky.social
@uofgsii.bsky.social
📣 Journal Editors at EMDS2025:Scotland Edition
Giuliana Clemente, Associate Editor (Immunology) @natcomms.nature.com, will be in Edinburgh at #EMDS2025 this week. Reach out to her to discuss your work.
@efis-immunology.bsky.social
@britsocimm.bsky.social
We have a new Postdoc position advertised as part of our recent long-term Wellcome funding to join an established Postdoc and technician. I’m so excited to explore the role of the glycocalyx in CNS-inflammation. So many tools and expertise to work with! www.jobs.manchester.ac.uk/Job/JobDetai...
📣 Journal Editors at EMDS2025:Scotland Edition
@gaiajexpmed.bsky.social, Deputy Editor @jem.org, will be in Edinburgh at #EMDS2025 next week. Reach out to her to discuss your work. Also, check out the Special Collection @jem.org on #macrophage & #dendriticcells
@efis-immunology.bsky.social
📣 Journal Editors at #EMDS2025
@claireolingy.bsky.social , Senior Editor at #Science #Immunology @aaas.org , will be at EMDS2025, so be sure to reach out to her to discuss your work.
@efis-immunology.bsky.social @britsocimm.bsky.social
Another exciting opportunity @dunnschool.bsky.social !
Come and be a colleague to a great group of scientists working on the fundamental mechanisms underlying disease, and how to transform health
Please help us find great applicants
Speaker Highlight - William (Bill) Agace
It's not too late to join us at #EMDS2025 to hear from Bill Agace about their work dissecting dendritic cell diversity in #Crohn's disease.
www.emds2025.com
@britsocimm.bsky.social @efis-immunology.bsky.social
[Background photo: Andrew Perry]
Still time to register for #EMDS2025 in the wonderful city of Edinburgh!
All details including invited & selected speakers and their abstract details at www.emds2025.com
Plus, the chance to take part in a traditional ceilidh!
