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Posts by Aga Gambus

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It’s official: the UK is rejoining Erasmus! πŸ‘πŸ‡ͺπŸ‡Ί

6 days ago 1813 458 57 85
Portrait of Professor Daniel Tennant, University of Birmingham, featured for The Sir Philip Randle Lecture at The Biochemical Society 2027 Awards.

Portrait of Professor Daniel Tennant, University of Birmingham, featured for The Sir Philip Randle Lecture at The Biochemical Society 2027 Awards.

We're delighted to announce Professor Daniel Tennant as the recipient of the 2027 Sir Philip Randle Lecture! Work in the Tennant Research Group - Birmingham UK has been instrumental in identifying new pathways through which cells modify their metabolism under hypoxia.

1 week ago 5 3 2 1

Congratulations πŸ₯‚ well deserved πŸ˜€

1 week ago 1 0 1 0

Proud to share the yeast telomerase structure, led by the talented @hongmiaohu.bsky.social in collaboration with the Wellinger and Chartrand labs. Discovered 37 years ago and took us nearly 7 years but totally worth the wait 😍.
www.science.org/doi/10.1126/...
www.youtube.com/watch?v=gFE4...

3 weeks ago 203 74 9 2
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β€œI think it’s a real mistake to forget where the pipeline for all this begins.”

John Diffley reflects on the importance of basic research, his mission to decode DNA replication and recreate it in the lab, and the scientific optimism of the 1960s that helped shape it.
www.crick.ac.uk/news/2026-03...

4 weeks ago 81 37 3 5
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Improving the solvent tolerance of E. coli by understanding the rules of accumulation at University of Birmingham on FindAPhD.com PhD Project - Improving the solvent tolerance of E. coli by understanding the rules of accumulation at University of Birmingham, listed on FindAPhD.com

PhD available with @overtonlab.bsky.social Sara Jabbari and me associated with our BBSRC sLoLa project!
www.findaphd.com/phds/project... (UK students only)

1 month ago 8 10 1 0
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We are excited to be recruiting into 3 Associate Professorship's in @oxfordbiochemistry.bsky.social. Come join us as a colleague and benefit from our vibrant and multidisciplinary environment. Reach out to me if you have any questions. Please repost! (tinyurl.com/48deybuu) (tinyurl.com/4pdvjaft).

1 month ago 107 125 1 4
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A modular genetic code expansion approach to site-specific lysine acylations A modular strategy combining genetic code expansion with a selective amide bond-forming reaction enables the site-specific installation of lysine acylations on folded proteins. Acylboronates react sel...

🚨 Our new paper is out! πŸ™Œ

Bioorthogonal reactions often create bulky, non-native linkages-great for labeling, but not ideal for installing natural PTMs.
We combine GCE with a chemoselective amide-bond forming reaction to install site-specific acylation PTMs.
www.cell.com/chem/fulltex...
1/4

1 month ago 50 15 2 1
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How do RNA molecules shape genome regulation in the nervous system? (AKAY_U26CASE) | Doctoral Training Partnership This is open to Home Fee Status candidates only. This PhD project will investigate how RNA modifications influence the activity of topoisomerase I (TOP1), a crucial enzyme that regulates DNA…

PhD position in our lab - 4-year funded by BBSRC and @nrpdtp.bsky.social in collaboration with @earlhaminst.bsky.social and Inspiralis Ltd. Open to UK fee qualifying students - UK citizens and citizens of Ireland (residency requirement), etc biodtp.norwichresearchpark.ac.uk/projects/how...

1 month ago 6 11 0 2
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A proteome-wide dependency map of protein interaction motifs - Nature Structural & Molecular Biology AmbjΓΈrn and Meeusen et al. functionally characterize all reported and a comprehensive set of predicted short linear motifs (SLiMs) using base-editing screens, identifying 450 reported and 264 predicte...

Happy to see our work on defining a dependency map of short linear motifs out. We use base editing screens to install more than 80000 mutations into SLiMs in more than 4000 proteins to determine their contribution to cell fitness. www.nature.com/articles/s41...

1 month ago 31 14 1 0

We are excited to be recruiting a new tenure track group leader in the Structural Studies Division at MRC LMB! It is an amazing place to start your own lab.
@mrclmb.bsky.social

Please get in touch if you have any questions.
www.nature.com/naturecareer...

1 month ago 51 54 1 0
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Post-replicative chromatin accessibility predicts cell fate change Knudsen and colleagues use repli-ATAC-seq to compare replicated and unreplicated chromatin in two models of cell identity change. They find that lineage-specific elements are accessible earlier in rep...

DNA replication globally disrupts the epigenome. But does this create a chromatin-access opportunity for TF binding to facilitate cell identity change? Now 𝐫𝐞𝐩π₯𝐒-𝐀𝐓𝐀𝐂-𝐬𝐞πͺ shows π˜₯𝘦 𝘯𝘰𝘷𝘰 chromatin opening & TF binding occurs specifically post-replication, in cellular differentiation & reprogramming!

1 month ago 67 26 1 0
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Best conference location ever! Thank you @fusionconf.bsky.social for the excellent DNA replication and repair conference πŸ‘πŸ‘πŸ‘

1 month ago 10 0 0 0

I have multiple positions available to join my lab from this summer: #postdoc, #student and #technician. Adverts to follow but see www.saurinlab.com for further details. #senescence, #mitosis, #cellcycle, #phosphorylation are the key areas. Email me if interested.

1 month ago 12 9 1 0
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To kickstart this new Bluesky account: We're hiring!
The Bertolin Lab @dundee.ac.uk is looking for a postdoc to work on DNA-end homeostasis & genome stability, funded by Wellcome Trust Award. Exciting science, fantastic environment, founding role in the lab.
Details in the flyer β€” get in touch! πŸ‘‡

2 months ago 33 30 2 1
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Research Fellow at University of Birmingham Discover Research Fellow jobs and more in higher education on jobs.ac.uk. Apply for further details on the top job board.

We are hiring 2 Postdoctoral fellows for our lab (www.mueller-lab.org): 1, Transcription control of metabolic adaptation in development (shorturl.at/oeG6U).
2, Semantic rules of developmental gene regulation (shorturl.at/KdHmJ)
#jobs #transcription #zebrafish #zebrafishrock #IZFS

2 months ago 10 5 2 3
Research Group Leader Tenure Track - Structural Studies - LMB 2775 - Medical Research Council Location: Cambridge. Vacancy: Research Group Leader Tenure Track - Structural Studies - LMB 2775. Closing Date: 16/03/2026, 23:55

Please spread the word: the Structural Studies Division @mrclmb.bsky.social is looking for a new tenure-track, independent group leader with an exciting plan in any area of Structural (Molecular & Cell) biology, in discovery biology and/or methods development. πŸ₯³

mrc.tal.net/vx/mobile-0/...

2 months ago 83 106 1 3
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Events for February 2026 06-07 July 2026 | Munich, GermanyDNA Replication and Its Impact on Genome and Chromatin MaintenanceWe are RepliFate, a European Training Doctoral Network dedicated to understanding howβ€―DNA replication...

We go live!!!

Join us Munich July5-7th to hear exciting research on #Replication by leaders in the field

AND !! registration is FREE πŸ₯³ (but mandatory) - we hope to see many in Munich 🍺 @helmholtzmunich.bsky.social

@replifate.bsky.social @epicrossborders.bsky.social

replifate.eu/event/meetin...

2 months ago 32 28 1 1
DNA translocation by the CMG helicase: the helical inchworm model Abstract. In all cells, hexameric helicases drive the unwinding of parental chromosomal DNA at replication forks to provide the single-stranded DNA templates required by replicative DNA polymerases. D...

Happy to share our perspective on the DNA translocation mechanism by the CMG helicase.

DNA translocation by the CMG helicase: the helical inchworm model url: portlandpress.com/biochemsoctr...

2 months ago 16 10 0 1

Don't miss the opportunity to attend exciting virtual talks from leading scientists in genome integrity, provided by the @genomeiinetwork.bsky.social! Next one is in a few days πŸ‘‡

2 months ago 8 5 1 0

πŸ“’ One more week to go... exciting fully funded #PhD position for UK candidates to work across #ICR and #Imperial on novel mechanisms in genome stability and #CancerResearch.

#PhDStudentship #LifeSciences #DNAReplication #CRISPR

3 months ago 5 6 0 0
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Great response so far for the DNA Repair Meeting in April 2026 ! 🧬

A few poster spots are still available.

✨ Early-bird registration extended to February 28th
✨ New invited speakers added: check the site: dnarepairmeeting-egmond2026.com

Don’t miss this outstanding meeting!

3 months ago 17 8 2 2
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One more upcoming appointment with great science via the Genome Integrity Italian Network (GiiN). Don't miss it, just join via the link πŸ‘‡

3 months ago 11 7 0 1
R for Biochemists 101
2 February 2026
Register online

R for Biochemists 101 2 February 2026 Register online

Sign up for the Biochemical Society’s original R course, R101! Suited for beginners, this course will teach you how to get data into R, and manipulating and visualising this using various methods. πŸ§ͺ https://ow.ly/O0ga50XNCuX

3 months ago 5 3 0 0

Alessandro Costa @costalaboratory.bsky.social, Dana Branzei and myself are co-organising the 2026 Machines on Genes meeting in beautiful Crete as the 94th Harden Conference hosted by @biochemsoc.bsky.social

Register now - lots of opportunities for selected talks www.eventsforce.net/biochemsoc/f...

3 months ago 38 17 1 3
PhD Opportunities – MRC AIM

Applications still OPEN for MRC fully funded PhD studentships πŸŽ“βœ¨
Join world-class researchers across our 3 partner universities:
πŸ”Ή @unibirmingham.bsky.social
πŸ”Ή @uniofleicester.bsky.social
πŸ”Ή @uniofnottingham.bsky.social
🌍 Open to applicants worldwide
πŸ‘‰ Apply more.bham.ac.uk/mrc-aim/phd-...

4 months ago 3 4 0 0
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Peptidomimetic Inhibition of DONSON/GINS as an experimental tool and potential an@cancer strategy at University of Birmingham on FindAPhD.com PhD Project - Peptidomimetic Inhibition of DONSON/GINS as an experimental tool and potential an@cancer strategy at University of Birmingham, listed on FindAPhD.com

πŸ’‘ PhD student position at the University of Birmingham, UK. Fully funded by MRC AIM doctoral training programme. 4 years. Open to πŸ‡¬πŸ‡§ πŸ‡ͺπŸ‡Ί & 🌎. DNA replication 🧬 . Collaboration with Prof Andrew Wilson (Chemistry). Deadline midday (GMT) 9 January 2026. Please share πŸ˜€πŸ‘

www.findaphd.com/phds/project...

4 months ago 6 6 0 0
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❄️The 2026 Winter Session of GIIN Webinars is here! Join us on the first Tuesday of each month at 5 PM (Rome) / 11 AM (NYC).
No pre-registration needed, simply join via Zoom: uniroma1.zoom.us/j/95149984403
Want reminders? Subscribe here: docs.google.com/forms/d/e/1F...

4 months ago 20 13 1 0
PhD Opportunities – MRC AIM

Applications are now open πŸš€for our fully funded Medical Research Council 4-year πŸŽ“studentships πŸŽ“ across our 3 partner institutions @unibirmingham.bsky.social @uniofleicester.bsky.social and @uniofnottingham.bsky.social

SeeπŸ‘‰ more.bham.ac.uk/mrc-aim/phd-... to find out more and apply *by 9 Jan 2026*.

4 months ago 3 2 1 0
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Peptidomimetic Inhibition of DONSON/GINS as an experimental tool and potential an@cancer strategy at University of Birmingham on FindAPhD.com PhD Project - Peptidomimetic Inhibition of DONSON/GINS as an experimental tool and potential an@cancer strategy at University of Birmingham, listed on FindAPhD.com

πŸ’‘ PhD student position at the University of Birmingham, UK. Fully funded by MRC AIM doctoral training programme. 4 years. Open to πŸ‡¬πŸ‡§ πŸ‡ͺπŸ‡Ί & 🌎. DNA replication 🧬 . Collaboration with Prof Andrew Wilson (Chemistry). Deadline midday (GMT) 9 January 2026. Please share πŸ˜€πŸ‘

www.findaphd.com/phds/project...

4 months ago 6 6 0 0