Editorial: Special Report
Nobel prize–winning Treg cells in autoimmune kidney diseases and transplantation
doi.org/10.1016/j.kint.2026.01.005
#OpenAccess #NephSky #MedSky #celltherapy #autoimmunity
@griffithperkins.bsky.social @adelaideuni.bsky.social @kuleuvenuniversity.bsky.social
XYZ of Statistics
Techniques to predict survival outcomes in nephrology: basics and traditional methods
doi.org/10.1016/j.kint.2024.08.041
#MedSky #NephSky #transplantation #KTx @sydney.edu.au
Reduced podocyte stiffness is a feature of proteinuric kidney disease
doi.org/10.1016/j.kint.2026.02.028
#MedSky #NephSky #kidneydisease #podocyte
N-propargylglycine restores survival by preventing calcium oxalate stone formation, tubular injury, and kidney dysfunction in a lethal mouse model of primary hyperoxaluria type 2
doi.org/10.1016/j.kint.2026.02.024
#MedSky #NephSky #OpenAccess
Finding the etiology of membranoproliferative glomerulonephritis
doi.org/10.1016/j.kint.2026.02.030
#NephSky #MedSky @mayoclinicpath.bsky.social
Complement inhibitors and B cell–modifying agents for IgA nephropathy—a Kidney Disease: Improving Global Outcomes (KDIGO) commentary
doi.org/10.1016/j.kint.2026.03.003
#OpenAccess #MedSky #NephSky #KDIGO #IgAN
📣Kidney International introduces new article type
Clinical Journey in Translational Medicine uses a case report format as a catalyst for discovery.
📝Details: doi.org/10.1016/j.kint.2026.04.004
👉Examples:
✨ doi.org/10.1016/j.kint.2026.01.034
✨ doi.org/10.1016/j.kint.2026.01.035
#NephSky #MedSky
A double-blind, randomized, placebo-controlled, phase 2 trial examined the efficacy and safety of monlunabant in adults with diabetic kidney disease
doi.org/10.1016/j.kint.2026.02.023
#NephSky #MedSky #OpenAccess #ckd #dkd #diabetes
Clinical Journey in Translational Medicine is a new Kidney International article type that uses a case report format as a catalyst for discovery. In the nephrology clinic, we regularly face important decisions with incomplete mechanistic or causal information as the science continues to evolve and the access to latest modalities is uneven. Each case advances understanding by tracing a focused "journey" of the clinical presentation, diagnostic pathway, and therapeutic reasoning and then pairing it with the mechanistic insight the case reveals through genetics, cell and molecular biology, pathology, biomarkers, or treatment-response. The goal for this article type is to show how bedside observations prompt targeted investigations and how those findings, in turn, refine diagnosis, prognosis, or therapy. We developed this format because translational progress is increasingly driven by granular phenotyping and precision tools that can be hard to connect to everyday clinical reasoning. "Clinical Journeys in Translational Medicine” makes this connection explicit, providing practical examples for integrating emerging science into patient care across diverse practice settings.
This looks cool
www.kidney-international.org/article/S008...
New journal type in @kidneyint.bsky.social
More details: www.kidney-international.org/content/auth...
Anti-PLA2R1 IgG-mediated podocyte PLA2R1 cleavage drives glomerular subepithelial immune complex deposition in membranous nephropathy
doi.org/10.1016/j.kint.2026.02.021
#NephSky #MedSky #OpenAccess #membranousnephropathy
Proteinase 3 Drives Murine Diabetic Kidney Disease by Mediating Caspase-3-dependent Apoptosis of Podocytes
doi.org/10.1016/j.kint.2026.02.020
#MedSky #NephSky #OpenAccess #diabetes #diabeticnephropathy
Evidence from multicenter clinical studies and humanized mouse models indicates that glomerular mesangial IgA2 deposition contributes to the pathogenesis of IgA nephropathy
doi.org/10.1016/j.kint.2026.02.018
#MedSky #NephSky #IgAN @nu-nephrology.bsky.social
Commentary
The expanding role of complement inhibitors in the treatment of IgA nephropathy
doi.org/10.1016/j.kint.2025.12.015
Original article: doi.org/10.1016/j.kint.2025.11.017
#MedSky #NephSky #IgAN @ucm.es
Coexistence of autosomal dominant polycystic kidney disease and primary hyperoxaluria type 3
Kidney stone is not uncommon in ADPKD but is not associated with #hyperoxaluria.
doi.org/10.1016/j.kint.2025.09.006
#NephSky #MedSky #ADPKD
Commentary
Percentiles of estimating glomerular filtration rate: a new personalized tool for detection of chronic kidney disease
doi.org/10.1016/j.kint.2025.12.010
Original article: doi.org/10.1016/j.kint.2025.11.009
#NephSky #MedSky #CKD #kidneydisease
Commentary
Pathologic diagnosis incorporating molecular monitoring highlights new pathophysiological mechanisms in kidney xenotransplantation
doi.org/10.1016/j.kint.2025.12.021
Original Article: doi.org/10.1016/j.kint.2025.11.018
#MedSky #NephSky #kidneypath #renalpath #transplantation
Kidney health for all: caring for people, protecting the planet
doi.org/10.1016/j.kint.2025.12.020
#OpenAccess #NephSky #MedSky #WorldKidneyDay
The relationship between obesity and chronic kidney disease: conclusions from a Kidney Disease: Improving Global Outcomes (KDIGO) Controversies Conference
doi.org/10.1016/j.kint.2025.09.019
#MedSky #NephSky #OpenAccess #KDIGO #CKD #Obesity #kidneydisease
Commentary
RNA methylation in acute kidney injury: opening up new therapeutic avenues
doi.org/10.1016/j.kint.2025.12.019
Original article: doi.org/10.1016/j.kint.2025.11.010
#MedSky #NephSky #AKI #acutekidneyinjury
Histoplasma capsulatum: a rare cause of interstitial nephritis
doi.org/10.1016/j.kint.2025.07.031
#NephSky #MedSky #PathSky
Brown tumor of the patella in a long-term hemodialysis patient
doi.org/10.1016/j.kint.2025.08.045
#NephSky #MedSky #hemodialysis
Kidney Disease: Improving Global Outcomes (KDIGO): navigating a rapidly changing landscape
doi.org/10.1016/j.kint.2025.12.028
#OpenAccess #MedSky #NephSky #CKD #chronickidneydisease #KDIGO
Tubular cell-specific platelet-derived growth factor-B drives formation of fibrogenic niches in kidney fibrosis
doi.org/10.1016/j.kint.2026.01.029
#NephSky #MedSky #OpenAccess @rwth.bsky.social
Increased Smoothened signaling promotes kidney fibrosis through inhibiting autophagy in fibroblasts
doi.org/10.1016/j.kint.2026.01.028
#OpenAccess #MedSky #NephSky #renalfibrosis #kidneyfibrosis
Klotho in the kidney distal convolution regulates urinary Klotho excretion and kidney calcium reabsorption, but not phosphate homeostasis
doi.org/10.1016/j.kint.2026.01.030
#NephSky #MedSky #OpenAccess @uzh-en.bsky.social
Polygenic Risk Scores and HLA Class II Variants are Biomarkers of Corticosteroid Response in Childhood Nephrotic Syndrome
doi.org/10.1016/j.kint.2026.01.026
#NephSky #MedSky #PedsNeph #pediatricnephrology
The splenic norepinephrine–β2-adrenergic receptor axis aggravates sepsis-associated acute kidney injury via neutrophil-mediated immunosuppression
doi.org/10.1016/j.kint.2026.01.024
#MedSky #NephSky
Association between the gut microbiota and estimated glomerular filtration rate in two Swedish population-based cohorts
doi.org/10.1016/j.kint.2026.01.021
#NephSky #MedSky #OpenAccess
