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Posts by Bryan Yipp

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Multimodal antigenic escape to GPRC5D-targeted T cell engagers in multiple myeloma - Nature Medicine Genomic and transcriptomic analysis of samples from patients with multiple myeloma, followed by in vitro validation, indicate mechanisms of antigen escape in response to GPRC5D T cell-engager talqueta...

www.nature.com/articles/s41...

5 days ago 0 0 0 0
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International study led by UCalgary explores why multiple myeloma patients often relapse after immunotherapy Understanding how tumour cells build resistance to treatment may impact future individualized cancer care

International study led by UCalgary explores why multiple myeloma patients often relapse after immunotherapy www.ucalgary.ca/news/interna...

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Skin inflammation and itch response are independently regulated by distinct nociceptor subsets Using scRNA-seq of skin-innervating neurons, Voisin et al. show that skin-projecting nociceptor subpopulations differentially integrate the inflammatory response during allergic contact dermatitis. Al...

Skin inflammation and itch response are independently regulated by distinct nociceptor subsets: Immunity www.cell.com/immunity/ful...

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The Rockefeller University » Symposium highlights SNFiRU's transition from incubator to engine Three years in, the Stavros Niarchos Foundation Institute for Global Infectious Disease Research has matured into a working pipeline connecting basic science and emerging therapies.

Three years in, the Stavros Niarchos Foundation Institute for Global Infectious Disease Research has matured into a working pipeline connecting basic science and emerging therapies:

2 weeks ago 3 1 0 0
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Meet the winners of the 2026 Gairdner Awards Annual prizes from a Canadian foundation recognize the most significant advances in human biology and medicine

www.theglobeandmail.com/canada/artic...

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U of C scientist lands $5.8 million to build biofilm research centre Microbial research has implications for drug-resistant infections, mental health and the corrosion of critical infrastructure.

calgaryherald.com/news/ucalgar...

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Neutrophil-derived Reactive Oxygen Species Mediate Doxorubicin-induced Cardiotoxicity and Skeletal Myopathy | American Journal of Physiology-Heart and Circulatory Physiology | American Physiological S... Doxorubicin (DOX), an effective chemotherapy, exhibits a narrow therapeutic index and detrimental adverse effects involving muscle atrophy and dysfunction. The precise mechanisms underlying DOX-mediat...

journals.physiology.org/doi/abs/10.1...

1 month ago 1 0 0 0
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Wired to Breathe: Inside the Lung-Brain Network Podcast Episode · The Unsung Lung Podcast · March 1 · 34m

podcasts.apple.com/ca/podcast/w...

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Wired to Breathe: Inside the Lung-Brain Network Podcast Episode · The Unsung Lung Podcast · March 1 · 34m

podcasts.apple.com/ca/podcast/w...

1 month ago 1 1 0 0
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Wired to Breathe: Inside the Lung-Brain Network

open.spotify.com/episode/3o5X...

1 month ago 1 0 0 0
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New issue alert 👉 www.cell.com/cell/current

On the cover, McCallum et al. depict a fluorescent micrograph showing a engineered biosensor strain in the mouse colon, illustrating how commensal bacteria can serve as in situ reporters of dynamic gut physiology.

2 months ago 5 2 2 1
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Immunobiology of the serous cavities Local immune function and cross-tissue communication in the serous cavities are reviewed.

A new Review discusses the immune makeup within the peritoneal, pleural, and pericardial cavities, including changes that occur during conditions such as cancer and endometriosis.

Learn more in #ScienceImmunology: https://scim.ag/4aeAAYr

2 months ago 22 5 0 0
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Hidalgo Lab | Mapping Innate Immunity Research on neutrophil biology, innate immunity, and cardiovascular disease at Yale School of Medicine. Led by Dr. Andrés Hidalgo.

I am excited to present our long-overdue lab website. Please visit us to learn who we are, our past work, and our current lines of research!
ahidalgolab.com

Thank you to Gerardo Barcia for his beautiful design and constant support in building it

2 months ago 18 6 0 0
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On the balance of knowledge - Nature Reviews Immunology Ruslan Medzhitov shares his thoughts on the balance between generating data and developing theories in immunology, with a focus on exploring the rules that govern complex systems.

Too much data, too little thinking.
A important essay from Ruslan Medzhitov on the importance of understanding data, not just generating it. A must read.
@Yale
www.nature.com/articles/s41...

2 months ago 73 27 2 3

13% success rates at #CIHR, is a really 87% fail rate for>4000 scientists. At a time when 🇨🇦 is investing millions to recruit more scientist into a broken funding environment. 🇨🇦, U need a strong science foundation 2 attract success. #CIHR, fix your science foundation, it is eroding in real time

2 months ago 56 17 3 4

Really sorry to hear that reviewers are abusing people with diseases. Hiding behind a screen does not take courage. It is cowardice. Bully tactics.

Sad commentary on the quality of reviewers. In person review panels hold reviewers accountable.
#CIHR being back in person review panels.

2 months ago 3 2 0 0
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We are deeply saddened by the passing of Professor Sir Nicholas White @moru-mip.bsky.social

Nick was a visionary in #malaria treatment whose work transformed global health.
He will be remembered with great respect and affection

Read our tribute 👉 www.tropicalmedicine.ox.ac.uk/news/profess...

2 months ago 2094 270 23 11
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Scientific Editor, Cell Cell has an opening for a full-time scientific editor. If you are a passionate, mission-driven team player who loves thinking broadly about science and wants to have a positive impact, we invite you t...

Cell is hiring!

Do you have a background in #neuroscience or #immunology? Better still, #neuroimmunology? Cell has an opening for a full-time scientific editor. Role will be based out of any one of our offices in Medford, MA, UK, Spain, Netherlands, China tinyurl.com/4ma236xn @cp-cell.bsky.social

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Over 100 years ago, platelets were observed to interact with neutrophils in blood clots

Eric Boilard & team now detail platelet-neutrophil interactions as more abundant in arthritic conditions, noting that neutrophils fail to migrate in the absence of platelets: doi.org/10.1172/JCI1...

2 months ago 6 1 1 0
Meet the Editors Meet the Editors

I’ve joined the editorial team at the journal Science, handling papers in infectious diseases, microbiology, host-microbe interactions, and related topics. I’ll be delighted to hear from you (by email) about exciting research studies. 🦠 #microsky #immunosky #virosky www.science.org/content/page...

2 months ago 40 2 4 1
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Pain-sensing neurons in the intestines play an important role in defending the body from threats.

New study led by the Artis Lab at @weillcornell.bsky.social shows TRPV1+ nociceptors in the gut activate tuft cells, leading to expulsion of parasites.

🔗 https://go.nature.com/4jTvO7k

2 months ago 15 3 0 0
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In 1943, Rockefeller’s Oswald Avery, Colin MacLeod, and Maclyn McCarty demonstrated that #DNA carries an organism’s genetic information. Their discovery launched a scientific revolution that’s placed genetics at the core of modern biomedical science.

#125YearsOfRockefeller

2 months ago 8 1 1 0
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The infection enigma: why some people die from typically harmless germs Millions of people worldwide carry genetic mutations that weaken their immune system.

Why do some people become severely ill from infections that leave others unscathed?

go.nature.com/457vTOK

3 months ago 19 6 1 1
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@cp-immunity.bsky.social preview of IRF4-driven circuit that reshapes alveolar macrophage identity and positions them as contributors to allergic pathophysiology
www.cell.com/immunity/ful...
www.cell.com/immunity/ful...

3 months ago 5 3 0 0
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The strain on scientific publishing Abstract. Scientists are increasingly overwhelmed by the volume of articles being published. The total number of articles indexed in Scopus and Web of Science has grown exponentially in recent years; ...

In the strain on scientific publishing, we showed that total publications have grown out of control. A huge part of that was guest edited special issues by groups like #MDPI and #Frontiers.

This ongoing practice is the largest delegation of editorial power academia has ever seen.

2/n

3 months ago 56 25 1 1
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Molecular, Cellular, Tissue, and Organismal Functions of Type III Interferons Type III interferons are essential immune mediators playing pleiotropic roles during health and disease. In this review, we highlight the molecular and cellular pathways that lead to the production of...

💥New paper alert!💥 What’s better than starting 2026 with an @annualreviews.bsky.social #Immunology, often a once-in-a-life honor ❤️?! Check it out if you want to know everything about type III interferons #IFN! Thanks to my wonderful team for their amazing work 🤗 doi.org/10.1146/annu...

3 months ago 57 21 1 0
Promotional graphic for the Type 2 Immunity, Homeostasis and Disease (3rd edition) symposium organized by VIB and Science Immunology. Includes the event title, topic, and a collage of headshots with names and affiliations of twelve speakers such as David Artis, Nora Barrett, Daniel Dwyer, and others. The event logo and question 'And you?' are also displayed.

Promotional graphic for the Type 2 Immunity, Homeostasis and Disease (3rd edition) symposium organized by VIB and Science Immunology. Includes the event title, topic, and a collage of headshots with names and affiliations of twelve speakers such as David Artis, Nora Barrett, Daniel Dwyer, and others. The event logo and question 'And you?' are also displayed.

The abstract deadline for #Type2Immunity26 in Ghent, co-organized by @vibtrainconf.bsky.social and #ScienceImmunology, is this Thursday, 8 January.

Learn more: vibbio.tech/3UwmTNk

Key dates:
🗓️26 January: Early-bird deadline
🗓️23 February: Final deadline
🗓️9–10 March: Meeting

3 months ago 6 2 0 0
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The silent pneumonia: Biofilms and the neurons that should feel them The pneumonia your neurons can’t detect

The silent pneumonia: Biofilms and the neurons that should feel them
open.substack.com/pub/ansyme/p...

3 months ago 0 0 0 0
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I am excited to share our new paper @JExpMed led by our one and only #Alejandra_Aroca

4 months ago 21 8 1 0
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The neutrophil collective Neutrophils are key immune cells that can acquire new traits across environments. This review covers their underlying biology and frames their organization as a two-compartment collective whose emerge...

www.cell.com/cell/fulltex...

4 months ago 0 0 0 0