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Posts by Simon Bullock

The third round is now open!

I will be hosting a webinar with my colleagues on Monday 27 April at 1pm. To sign up please go to: shorturl.at/Vuwib

International applicants are eligible to apply!

15 hours ago 1 3 0 0
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Going to #DynamicCellVI ? Be sure to pop by the poster flash talks and poster session on Wednesday to learn how to make any dual-camera microscope multispectral ! If you pop by the poster you can see a cool 3D printed model of the system!

1 day ago 4 2 0 0
Announcement for a three-year Rising Talent Fellowship for Black heritage postdoctoral scientists at MRC Laboratory of Molecular Biology.

Announcement for a three-year Rising Talent Fellowship for Black heritage postdoctoral scientists at MRC Laboratory of Molecular Biology.

The LMB Rising Talent Fellowship is open for new applicants!

Aimed at Black heritage scientists, the Fellowship offers a 3-year postdoctoral position beginning Oct-Dec 2026.

Visit our website for more info: mrclmb.ac.uk/careers-and-...

Please circulate this post to anyone who might be interested!

5 days ago 10 11 0 2
Three-year funded postdoctoral fellowship for scientists returning after a 12-month career break, deadline May 17, 2026.

Three-year funded postdoctoral fellowship for scientists returning after a 12-month career break, deadline May 17, 2026.

The LMB is proud to launch the Career Returner Fellowship, a three-year, fully funded postdoc placement for scientists who have had a career break of over 1 year.

Applications are open now!

More details: mrclmb.ac.uk/careers-and-...

Please share this post with anyone who may be interested!

6 days ago 15 17 0 2
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Dissecting the RNA-binding capacity of the multi-RRM protein Rrm4 essential for endosomal mRNA transport Abstract. RNA-binding proteins (RBPs) utilize multiple RNA-binding domains (RBDs) to engage with extensive messenger RNA (mRNA) networks. Understanding the

Breakthrough article 😊
Joint effort of teams Zarnack & König & Feldbrügge clarifies how multiple RNA-binding domains cooperate to identify functional important binding sites in vivo
doi.org/10.1093/nar/...
@zarnack-group.bsky.social
@könig-lab.bsky.social
@mibinet.bsky.social
#EMBOrnaLocalization

2 weeks ago 25 16 1 1

Germ cells have their own versions of core transcription factors and fertility depends on them.
We're hiring a PhD student to figure out how! 📢
Fly genetics + proteomics + genomics. Fully funded.
Aarhus University 🇩🇰
Deadline May 1 👇

Please share with anyone who might be interested!

2 weeks ago 33 41 0 4
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Check out our first lab preprint: A real team effort to understand the Plasmodium GAPM proteins, which form part of a essential bridge between the parasite's cytoskeleton and motility apparatus. Below is a sneak peek of some beautiful microscopy - light and electron! www.biorxiv.org/content/10.6...

3 weeks ago 70 25 3 4
3D molecular structure of an AMPA receptor showing its complex assembly, with distinct coloured subunits.

3D molecular structure of an AMPA receptor showing its complex assembly, with distinct coloured subunits.

Explore how AMPA receptors drive synaptic signalling as a #postdoc in @igreger.bsky.social’s group, combining advanced structural biology (including #cryoEM & #cryoET) with imaging and electrophysiology.
More details: www.nature.com/naturecareer...
Apply by 19 APR
#PostdocJobs #ScienceJobs

3 weeks ago 8 1 0 0
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Chief Executive Officer | Inspired Selection

A unique opportunity to lead the most wonderful company in scientific publishing (I might be slightly biased here). The Company of Biologists are searching for a CEO.

www.inspiredselection.com/jobs/jo00000...

3 weeks ago 34 33 0 2
Scientists engaging with public in microscope-based activities.

Scientists engaging with public in microscope-based activities.

Last week, LMB scientists attended Cambridge Festival to showcase the intricate beauty of biology through microscopy 🔬

We shared insights into LMB research on embryo development, connectomics and neurodegeneration with around 330 visitors!

Read more: mrclmb.ac.uk/news-events/...

#LMBNews

3 weeks ago 8 2 0 0
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Excited to share our work on the structure and function of cytoplasmic lattices within mouse embryos. A collaborative effort with @niakanlab.bsky.social and work led by @kashishsingh.bsky.social and @inaharasimov.bsky.social . It is now out on BioRxiv: www.biorxiv.org/content/10.6...

4 weeks ago 190 77 6 9

Join us to establish your lab @lmcb-ucl.bsky.social @ucl.ac.uk - very supportive environment & state-of-the-art imaging, mass spec and genomics tech platforms!

4 weeks ago 7 3 1 1
3D molecular model showing a complex protein structure with blue, green, pink, and gray regions bound to a twisted blue DNA strand.

3D molecular model showing a complex protein structure with blue, green, pink, and gray regions bound to a twisted blue DNA strand.

📣 Fully funded PhD position available!
Join @suyangzhang.bsky.social’s group to uncover how human cells coordinate RNA transcription and splicing. You’ll use biochemical, structural & cellular approaches, including #cryoEM.
Apply by 14th April.
More details: mrclmb.ac.uk/careers-and-...
#PhDposition

4 weeks ago 13 11 0 1
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Primordial germ cells experience increasing physical confinement and DNA damage during migration in the mouse embryo Mammalian PGCs face a challenging journey to the gonads, and experience DNA damage as they navigate through confined spaces.

Cool work from the McDole lab just published. Primordial germ cells have to endure some pretty tight spaces on their journey!

www.science.org/doi/10.1126/...

1 month ago 10 5 0 1
Microscopic view of a glowing, irregularly shaped primordial germ cell with long protrusions with purple and green fluorescence against a dark blue background.

Microscopic view of a glowing, irregularly shaped primordial germ cell with long protrusions with purple and green fluorescence against a dark blue background.

How do primordial germ cells (PGCs) migrate across a developing embryo?

#LMBResearch from Katharine Goodwin and Kate McDole (@cellbiol-mrclmb.bsky.social) uncovers the mechanisms PGCs use in mouse embryos to navigate this long and surprisingly risky journey.

Read more: mrclmb.ac.uk/news-events/...

1 month ago 17 9 0 1

Thanks to co-authors Li Jin, Nanami Satoh and @marta-shahbazi.bsky.social, who made important contributions (6/6)

1 month ago 2 0 0 0
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This work, which was led by a terrific postdoc @lucas-albacete-x2.bsky.social, paves the way for dissecting molecular mechanisms that link localisation of various organelles to gene expression regulation (5/5).

1 month ago 5 0 1 0

Our findings indicate that perinuclear localisation of organelles promotes expression of genes that protect against damage. Remarkably, whereas some genes depend on localisation of a single organelle for robust activation, others depend on a specific combination of organelles (4/n)

1 month ago 2 0 1 0
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Is organelle repositioning an epiphenomenon or part of the adaptive response to stress? We tackled this question in multiple ways, including by inducible dispersion of specific organelles via tethering to an active kinesin motor (3/n)

1 month ago 2 0 1 0

We show that perinuclear clustering of organelles is a widespread response to oxidative stress and is mediated by PKC and a non-canonical dynein activation mechanism (2/n)

1 month ago 2 0 1 0
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Delighted to announce the posting of our latest preprint, which links stress-induced relocalisation of multiple organelles by dynein to adaptive changes in gene expression in the nucleus (1/n) 🧵

www.biorxiv.org/content/10.6...

1 month ago 42 19 1 4
Cambridge festival advert

Cambridge festival advert

Ever wondered what microscopes can reveal? 🔬

Visit us at the Cambridge Festival (@cambridgefestival.bsky.social) to find out more!

📆 21/03
⏰ 11am-4pm
📍Cambridge Academy for Science and Technology

#CamFest

1 month ago 5 2 0 0
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A Rab1 interactome illuminates a dual role in #autophagy and membrane #trafficking, say Alexander R. van Vliet, Sean Munro and colleagues
@mrclmb.bsky.social: rupress.org/jcb/article/...

📕 Part of #Autophagy 2026 👉 rupress.org/jcb/collecti...
#GRC

1 month ago 13 3 0 0

www.biorxiv.org/content/10.6... Amazing work by Kris and gang! For the first time we have been able to image division ring components live in Sulfolobus. And guess what - CdvA is asymmetrically inherited.

1 month ago 48 20 1 2
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We are looking for RNA enthusiasts to join us at the @uniregensburg.bsky.social as a junior group leader! Our university offer excellent infrastructure and collaboration opportunities for ground breaking RNA research. Please RT @jrrnascientists.bsky.social @rnasociety.bsky.social

1 month ago 11 9 0 0
Kiss-intro IMPRS-LM stands for International Max Planck Research School for Living Matter. We are interested in the molecular, chemical and physical properties

You are passionate about ubiquitin, proteostasis and cellular biochemistry and want to be part of a collaborative, ambitious, excited and fun team? I am recruiting PhD students via the @imprs-lm.bsky.social graduate school:
www.imprs-lm.mpg.de/index.php/le...
(2/3)

1 month ago 15 10 1 0
Research Support Officer - Cell Biology - Dr Madeline Lancaster - LMB 2788 - Medical Research Council Location: Cambridge. Vacancy: Research Support Officer - Cell Biology - Dr Madeline Lancaster - LMB 2788. Closing Date: 25/03/2026, 23:55

📣🧠 We're looking for someone to join the Lancaster Lab family as a Research Support Officer (maternity cover).

You'll be studying the origins of human brain specialisations using brain organoids, as part of a great team at one of the world's great research environments.

mrc.tal.net/vx/mobile-0/...

1 month ago 1 2 0 0

Join us in beautiful Portugal for the best & most comprehensive meeting on RNA localization and local translation! > 30 talks will be selected from abstracts. Held for over 30 years, this meeting is small enough to meet leaders in the field, yet big enough to cover a breadth of cutting-edge science.

1 month ago 8 4 1 0

Do you work on DNA or RNA protein complexes? 🧬

Come to Machines on Genes this June in Crete! ☀️

Super early discount is ending this Sunday so register now! 😃

1 month ago 22 14 0 0
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Join us!

1 month ago 16 6 1 0