Why are fungi so important, and what role does the Westerdijk Institute play?

We had the pleasure of hosting Stichting van Waarden, where our director Wieland Meyer and @fhagen.bsky.social  shared insights into how #fungi contribute to One Health—keeping ecosystems, animals, and humans in balance

Tonight, Prof. @fhagen.bsky.social will be on NTR Focus to discuss the importance of antifungal resistance.

He discusses:
⭐The importance of mycological research
⭐The value of the largest collection of fungi in the world
⭐What is antifungal resistance, and why is it a problem?

Links in comments

Global guideline for the diagnosis and management of candidiasis: an initiative of the ECMM in cooperation with ISHAM and ASM Candida species are the predominant cause of fungal infections in patients treated in hospital, contributing substantially to morbidity and mortality. Candidaemia and other forms of invasive candidias...

🌍 New Global Guideline for #Candida Infections 🌍
Team led by @rosannesprute.bsky.social and myself @unicologne.bsky.social: 100+ experts, 35 countries, all UN regions release evidence-based recommendations
@thelancetinfdis.bsky.social: www.thelancet.com/journals/lan... #FungalInfections #Healthcare

Has the environmental niche of Candidozyma auris finally been found? South African brown locusts, Locustana pardalina, hosts fluconazole resistant Candidozyma (Candida) auris (Clade III) #preprint doi.org/10.1101/2025... @youngecmm.bsky.social @ishamycology.bsky.social @escmid.bsky.social

We've created a starter pack so that you can follow members of the MRC Centre for Medical Mycology in one go! We'll be updating this pack as members join Bluesky! 🦋

bsky.app/starter-pack...

Subscribe to this list to keep up to date with all of the incredible research coming out of the CMM 🍄🔬👩‍🔬

Keep the hospital clean: diagnostic performance of ten different molecular and culture-based methods to detect Candidozyma auris #preprint @medrxivpreprint.bsky.social @westerdijkinst.bsky.social #AmsterdamUMC @ishamycology.bsky.social @escmid.bsky.social doi.org/10.1101/2025...

Imported Systemic Endemic Mycoses in Spain 1997–2021: An Analysis of a National Hospital Database Background Systemic endemic mycoses are systemic fungal infections typically found in tropical and subtropical regions. Their global incidence is rising, including in nonendemic countries, mainly du...

Imported Systemic Endemic Mycoses in Spain 1997–2021:
An Analysis of a National Hospital Database @ishamycology.bsky.social @youngecmm.bsky.social @escmid.bsky.social #Mycoses #openaccess doi.org/10.1111/myc....

What is antifungal resistance and why is it important 🤔?

@fhagen.bsky.social was interviewed by NTR Focus.

Here, he discusses:
⭐ The importance of the mycological research at Westerdijk Institute
⭐Why is antifungal resistance a problem?

Interview available on NPO2 on the 20th of February at 20:50

De novo genome assembly and comparative genome analysis of the novel human fungal pathogen Trichosporon austroamericanum type-strain CBS 17435 @westerdijkinst.bsky.social @pasteur.fr @agenciafapesp.bsky.social Preprint at Research Square via doi.org/10.21203/rs....

Emerging Cases of Cat-Transmitted Sporotrichosis Driven by Sporothrix brasiliensis in Northeast Brazil - Mycopathologia Cat-transmitted sporotrichosis is caused by the emerging fungal pathogen Sporothrix brasiliensis and constitutes a significant public health issue that affects people living in resource-poor urban cen...

Emerging #Sporothrix brasiliensis is fueling a cat-transmitted sporotrichosis #outbreak in Northeast Brazil. Over 1,100 cases identified in Recife's metro region (2016-2021), with zoonotic transmission linked to Rio de Janeiro strains.
Link: link.springer.com/article/10.1...
#PublicHealth #Zoonoses

Analyses of the Genetic Diversity and Population Structures of Sporothrix spp. Clinical Isolates from Paraíba, Brazil Sporotrichosis is a subcutaneous mycosis of global distribution, capable of affecting both humans and animals, and caused by species of the genus Sporothrix spp. This study aimed to evaluate the genet...

Our new study explores the genetic diversity and population structure of #Sporothrix spp. clinical isolates in #Paraíba, Brazil! S. brasiliensis was the predominant species, highlighting the importance of molecular surveillance. www.mdpi.com/2309-608X/10... #Sporotrichosis #Mycology #UNIFESP #UFPB

Typing of feces-derived Candida albicans strains using a novel seven-locus microsatellite panel reveals associations with yeast phenotype in individuals with inflammatory bowel disease Abstract. Inflammatory diseases of the human gastrointestinal tract are affected by the microbes that reside in the mucosal surfaces. Patients with inflamm

Typing of feces-derived Candida albicans strains using a novel seven-locus microsatellite panel reveals associations with yeast phenotype in individuals with inflammatory bowel disease #OpenAccess @femsmicro.bsky.social @westerdijkinst.bsky.social @knaw-nl.bsky.social

doi.org/10.1093/fems...

Mortality Patterns in Candidemia: Insights from a Multispecies Analysis Using a Global Research Network Abstract. Understanding the impact of different Candida species on patient outcomes is crucial for effective management and treatment strategies. This stud

Mortality Patterns in Candidemia: Insights from a Multispecies Analysis Using a Global Research Network #MedicalMycology #ISHAM doi.org/10.1093/mmy/...

Draft genome sequence of Aureobasidium pullulans ATCC15233 | Microbiology Resource Announcements Aureobasidium pullulans is an oligotrophic, saprophytic, and polymorphic yeast-like fungus with ubiquitous distribution, naturally occurring in a variety of terrestrial and aquatic environments (1). The fungus is primarily used for the production of pullulan, a new food additive, with applications in the food, pharmaceutical, and medical industries (2, 3). To elucidate the pullulan synthesis and regulation mechanism of A. pullulans, it is of great significance to sequence and analyze the whole genome. Therefore, we report the genome sequence of A. pullulans ATCC15233.

Draft genome sequence of Aureobasidium pullulans ATCC15233 (= CBS 249.65) #MRA @asm.org doi.org/10.1128/mra....

Strain available via the CBS Culture Collection @westerdijkinst.bsky.social

New Perspectives on Antimicrobial Agents: Rezafungin | Antimicrobial Agents and Chemotherapy Candidemia and invasive candidiasis (IC) remain challenging infections with morbidity and mortality estimated around 40% (1). These infections are commonly associated with healthcare exposure, especia...

New Perspectives on Antimicrobial Agents: Rezafungin #AAC @asm.org doi.org/10.1128/aac....

Candida auris MIC testing by EUCAST and clinical and laboratory standards institute broth microdilution, and gradient diffusion strips; to be or not to be amphotericin B resistant? @escmid.bsky.social #EFISG #EUCAST doi.org/10.1016/j.cm...

Hypoxylon lateripigmentum infection mimicking a sebaceous nevus @escmid.bsky.social #EFISG #openaccess doi.org/10.1016/j.cm...

Invasive fungal disease in the immunocompromised host: changing epidemiology, new antifungal therapies, and management challenges @escmid.bsky.social #EFISG doi.org/10.1016/j.cm...

Logo of OrthoHMM, a novel software for HMM-based inference of orthologous groups of genes

Benchmarking analysis of OrthoHMM and previously published algorithms. OrthoHMM has better precision, recall, and FMI scores. Benchmarking was conducted against the Orthobench dataset of expertly curated orthogroups

NEW preprint!🥳

Orthogroups are a prerequisite for comparative genomics and Tree of Life inquiries

Introducing #OrthoHMM, software that improves the inference of orthogroups (blue in fig)

OrthoHMM may refine our understanding of genome evolution and the Tree of Life

🔗 tinyurl.com/4s9mwxz6

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🎙️ New Interview Alert

The Scientist sat down with @fhagen.bsky.social from the Westerdijk Institute to discuss a global health challenge: the silent pandemic of antifungal resistance.

Read here:
www.the-scientist.com/the-silent-p...

The Silent Pandemic of Antifungal Resistance As the world grapples with antimicrobial-resistant bacteria, another insidious threat looms large: drug-resistant fungi.

The Silent Pandemic of Antifungal Resistance www.the-scientist.com/the-silent-p... interview with @fhagen.bsky.social #fungi

Dit is mijn volgende project, de verschillende stadia van het witpootglinsterkopje, misschien wel de mooiste slijmzwam die bestaat, spectaculair mooi. Wordt vervolgd! #slimemolds #fungifriends

Aspergillus was named by Pier Antonio Micheli, an Italian priest and biologist. The molds resembled an aspergillum, a holy water sprinkler.

Descriptions of Medical Fungi | CABI Books

Descriptions of Medical Fungi 4th Edition, now available to purchase as both hardback and ebook from CAB International.
Updated names, beautiful images, AFST profiles. Perfect for use in the lab.

www.cabidigitallibrary.org/doi/10.1079/...