With all the cuts to research funding in European countries, everyone is turning to the ERC...

The ERC should be a source of supplementary funding, not a substitute.

Every country in Europe must invest in basic research and increase its budgets!!!!

✨ New paper out in #JACS! We looked at the intrinsically disordered CTD tail of #Hsp90 often seen as a passive linker. Turns out, it’s not.
#StructuralBiology #Biophysics #EPR #NMR
pubs.acs.org/doi/10.1021/...

#ESR #CNRS #veilleESR

Vu sur un autre réseau, je reposte 💯

Message clair, net et précis de Carine Tisné, sur la baisse du budget du CNRS et la situation de la recherche française qui ne cesse de se dégrader depuis 20 ans.

Returning from an amazing Proteostasis meeting, with lots of new ideas & grateful for great feedback about our mitochondrial-import work.

Traveling back from Frankfurt to Vienna by train, I am reminded of the CO2-emissions savings of train vs. plane travel. Also in 2026, I won't take a plane.

You asked, we listened. Millions of AI-predicted protein complex structures are now available in the #AlphaFold Database.

This spans homodimers from 20 of the most studied species, including humans, as well as the World Health Organization’s priority pathogens list.

www.ebi.ac.uk/about/news/t...

Discover and share the CBS Montpellier starter pack, to follow current and formers members of the Centre de Biologie Structurale on Bluesky.

go.bsky.app/G682pvP
@cnrs.fr
@inserm.fr
@umontpellier.bsky.social

This graph basically shows that the MSCA are, as of now, useless unless the EU governance does something about it 🧪

The killing of Alex Pretti is a heartbreaking tragedy. It should also be a wake-up call to every American, regardless of party, that many of our core values as a nation are increasingly under assault.

EMBO Practical Course: Structural dynamics, interactions & function of biological macromolecules by NMR

EMBO Practical Course: Structural dynamics, interactions & function of biological macromolecules by NMR @embo.org
📅 July 24–31, 2026
📍 BNMRZ, Technical University of Munich (Garching)
📝 Registration open | Deadline: Apr 17, 2026
🔗 embo2026.bnmrz.org

#NMR #StructuralBiology #EMBO #NMRchat 🧲

Join us in Montpellier in June 2026 for the second edition of the European South Atlantic Biophysical conference
#ESAB2026

The latest article from a great collaboration between the Buchner Lab, @sattler-lab.bsky.social and the Rosenzweig Lab!

Schematic showing the function of Sgt1 in yeast.

Our latest work is now out in @cp-molcell.bsky.social !
We have looked at Sgt1, an essential Hsp90 co-chaperone in yeast. We determined its interaction with Hs90 and showed that it stabilises the chaperone-client complex and prevents its dissociation by Aha1.

www.cell.com/molecular-ce...

The essential co-chaperone Sgt1 regulates client dwell time in the Hsp90 chaperone cycle Engler et al. define the Sgt1-specific domain as essential for the Sgt1 chaperone function in yeast. Through structural and biochemical analyses, they uncover unique interactions of Sgt1 with Hsp90 and client proteins that enhance client maturation efficiency. Sgt1 stabilizes Hsp90-client complexes by preventing their dissociation mediated by the co-chaperone Aha1.

Online Now: The essential co-chaperone Sgt1 regulates client dwell time in the Hsp90 chaperone cycle Online now:

Congrats to our lab member Philipp, who defended his PhD this week! 🎓🎉

Watch Robert Quast @rbquast.bsky.social from our Team presenting our work on single molecule #FRET on #GPCR in the first FBI Connect webainar !

We are hiring a 2-year postdoctoral researcher to join our Membrane Biophysics team at the CBS in Montpellier. Join us to reinvent Atomic Force Microscopy to image the most common interface on our planet: the surface of water @membranesbiophy.bsky.social @cbsmontpellier.bsky.social

graphical abstract showing the combination of techniques used to analyze the dynamics of a de novo enzyme.

Our latest work is out! We combined #NMR with #Crystallography, #MD, and #ProteinMPNN to analyze the conformational dynamics of a de novo enzyme and redesigned it! Great collaboration between
@cathleenzeymer.bsky.social and the @sattler-lab.bsky.social.

www.cell.com/structure/fu...

Don’t miss this opportunity to work with a fantastic mentor, a great team, in a beautiful city of France!

Highly endowed ERC Synergy Grant for Prof. Johannes Buchner Disease-causing proteins – ERC Synergy Grant for research at TUM on the role of chaperone “helper proteins.”

Misfolded proteins can cause #Alzheimers, #Parkinsons and #Cancer. Johannes Buchner, part of the CHAPEROME team, receives an #ERC Synergy Grant to study how chaperone #proteins keep cells healthy: go.tum.de/904052 👏

#ERCSyG #biotechnology
@erc.europa.eu

📷A. Heddergott

We are hiring a PhD student!!
The project starts as early as January 2026 and is fully funded for three years.
Everyone with interest in NMR-centered structural biochemistry of nucleic acid-protein interactions in virus-infected cells, get in contact!
biochemie.uni-greifswald.de/forschung/fo...

Lancement ce jour du projet d'extension de notre laboratoire. 1100m² de nouveaux espaces et 280m² rehabilités.
Merci pour leur soutien à nos tutelles et nos partenaires.
@inserm.fr @cnrs.fr @umontpellier.bsky.social
@occitanie.bsky.social @villedemontpellier.bsky.social
& l'Etat

Thrilled to share my first corresponding author paper as a project leader in @hillerlab.bsky.social ‪ Amazing work from first author @annaleder.bsky.social We discovered multi-chaperone condensates in the ER that revolutionise the current vision of protein folding!
www.nature.com/articles/s41...

BNMRZ Symposium Ultra-Highfield NMR and 4D Structural Biology – From Mechanisms to Therapies, November 6–7, 2025, TUM Institute for Advanced Study, Garching @ias-tum.bsky.social registration opens soon www.bnmrz.org/4dstructbiol #BNMRZ #NMRchat #NMR 🧲

Molecular mechanisms of biomolecular condensate formation in Drosophila melanogaster siRNA biogenesis Abstract. Biogenesis of small interfering RNAs (siRNA) in Drosophila melanogaster involves the processing of double-stranded RNA (dsRNA) by Dcr-2 with Loqs

New paper in collaboration with the Förstemann Lab & Boekhoven Lab is out! Combining #NMR & mutational analysis, we characterize the unique features of the #Ago2 IDR region which drives Ago2/RNA #condensate formation.
doi.org/10.1093/nar/...
@clarahipp.bsky.social

J'entends Aurore Bergé sur @franceinfo.fr expliquer que les gens sont contres la loi Duplomb parce qu'ils sont désinformés.
Désinformés par qui ? 14 sociétés savantes ? La ligue contre le cancer ? Le CNRS écologie environnement ?

Very happy to share our preprint on heavy metal associated (HMA) domain-containing rice proteins bound by the rice blast MAX effector AVR-Pia! 🌾

You designed binders for your favourite protein and wish there was a way to experimentally screen them within 24h w/ only a set of pipettes and a plate reader?

Check out our Cell-Free 2-Hybrid approach (CF2H)

Full post: tinyurl.com/48cz5nb6

Preprint: www.biorxiv.org/cgi/content/...

One of our group members @clarahipp.bsky.social had the great opportunity to attend the Nobel Laureate Meeting last week in sunny Lindau ☀️
#lino25

Quantifying the carbon footprint of conference travel: the case of NMR meetings Abstract. Conference travel contributes to the climate footprint of academic research. Here, we provide a quantitative estimate of the carbon emissions associated with conference attendance by analyzi...

Read our preprint related to an important topic: climate change 👉 mr.copernicus.org/preprints/mr...
As scientists, we rely on data for rational decisions. Climate science is clear: human-made CO₂ emissions are changing our climate fast. But what can we do about it—individually or as a community? 1/n

Unique conformational dynamics and protein recognition of A-to-I hyper-edited dsRNA Abstract. Adenosine-to-inosine (A-to-I) editing is a highly abundant modification of double-stranded RNA (dsRNA) and plays an important role in posttranscr

📢 Paper with @sattler-lab.bsky.social now published in @narjournal.bsky.social ! doi.org/10.1093/nar/... We combine #NMR, #SAXS, and #MD to construct conformational ensembles, showing that A-to-I hyper-editing leads to significant structural dynamics. MD simulations by @piompons.bsky.social