Today, in #preprinthub2 Chloe and Meredith @uvaimmunology.bsky.social will present a #preprint from the Martin Vaeth lab @uni-wuerzburg.de on how the glucose transporter GLUT3 controls #Treg function 🍬🚡🕹️ #immunosky

www.biorxiv.org/content/10.6...

Das Cover der Akademie Aktuell zeigt einen Mann, der sich ein barockes Deckengemälde anschaut.

Die neue #AkademieAktuell ist da! Diesmal im Fokus: Barocke Deckenmalerei trifft auf KI & Virtual Reality – wie digitale Technologien 400 Jahre alte Kunst neu erlebbar machen.

Jetzt das E-Paper lesen: tiny.badw.de/zYRRBq

#Barock #DigitalHumanities #Kulturerbe @lmu.de @matteoburioni.bsky.social

Mich hat es sehr gefreut, dass in "Akademie Aktuell", der Zeitschrift der Bayerische Akademie der Wissenschaften über unsere Forschungsarbeiten zu T-Zell-Antworten nach SARS-CoV-2 Impfung berichtet wird.

Direkter Link zum PDF unseres Artikels: badw.de/fileadmin/pu...

@fau.de, @badw.de

Landmark ancient-genome study shows surprise acceleration of human evolution Data from more than 15,000 ancient people reveal natural selection of hundreds of genes linked to immunity, skin tone, behaviour and other traits.

Landmark ancient-genome study shows surprise acceleration of human evolution www.nature.com/articles/d41...

Happy to be nominated for the 2026 FAU Award for Doctoral Supervision.

blogs.fau.de/proko/fau-aw...

Good mentoring is any supervisor's job and moral obligation. But good mentoring will also make your research better, egoistically speaking. So there's really no reason not to put emphasis on this.

Why I study immune responses to vaccination:

"Pediatric vaccines have saved the lives of 154 million children since 1974. Independently, COVID-19 (COVID) vaccines saved an estimated 20 million lives in 2021 alone. The efficacy of almost all human vaccines is dependent on immunological memory."

A Cancer Treatment That Does More Than Scientists Thought CAR-T cell therapy, originally developed for cancer, is showing ever more promise as a treatment for autoimmune diseases.

A patient with three rare autoimmune diseases in Germany has been symptom-free for over a year after a single dose of CAR T cell therapy. Avery Posey, PhD addresses risks + new developments for adapting the #immunotherapy as a treatment for autoimmune diseases in The Atlantic: https://bit.ly/4dG3nIY

We are recruiting 1-2 postdoctoral fellows to investigate the specificity of human anti-influenza virus antibodies, and to determine how these antibodies impact global antigenic drift of influenza viruses.

Join our lab at Penn in Philly. Reach out if you are interested in applying! Please repost!

We’re unwrapping a new method today at @mskcancercenter.bsky.social. Led by Sydney Blattman, Nabih Maslah, and @austinv11.com with @danapeer.bsky.social, @ronanchaligne.bsky.social and @10xgenomics.bsky.social, we present GIFT: Genotyping In Fixed Transcriptomes www.biorxiv.org/content/10.6... 1/n

Balancing the efficacy and safety of chimeric antigen receptor T-cell therapy by affinity combination
www.nature.com/articles/s41... @natcomms.nature.com

CD19 CAR-T therapy induces remission in refractory autoimmune hemolytic anemia with ITP and antiphospholipid syndrome @cp-med.bsky.social
www.cell.com/med/abstract...

Do you think you would have discovered a gorilla hiding in plain sight in your data? We found that you are 3 times less likely to do so if you have a specific hypothesis in mind. *A hypothesis is a liability*
(Night Science recap, Day 5)
genomebiology.biomedcentral.com/articles/10....

Does anyone have serum/plasma from a cohort of (ambulatory) patients with herpes zoster (shingles) ? A small cohort would be fine. We will test if they have auto-Abs against type I IFNs, as the risk of zoster increases over 50 yo. Please RT or contact me !

Acute and chronic infections drive distinct trajectories in human memory CD4+ T cell formation Different clinical courses of HCV infection shape CD4+ T cell immunity. Reinscheid et al. show that a stem-like subset of CD4+ T cells arising during chronic infection is maintained after successful a...

"our findings delineate antigen-specific CD4+ T cell fates in different courses of human viral infections, identifying stem-like subsets as potential immunotherapeutic targets and highlighting the need for tailored strategies to re-direct or boost CD4+ T cell responses." #Immunology 🧪🩺

Monthly median Received to Accepted time (days) at Nature Genetics

Eine herausragende Stätte für die Erforschung der Altsteinzeit Seit 1964 forscht die FAU in der Sesselfelsgrotte im Altmühltal…

Die Sesselfelsgrotte im Altmühltal ist ein ganz besonderer Ort. Seit 1964 wird sie von der FAU erforscht und brachte erstaunliche Funde hervor. Unter anderem entdeckten Forschende einen Neandertaler-Fötus dessen Alter auf 55.000 Jahre geschätzt wird.

www.fau.de/2026/03/news...

Postdoctoral Researcher – AI-based Multi-Omics in Computational Biomedicine (m/f/d) Patient care at the highest level, excellent research and teaching, and cutting-edge medicine and diagnostics – that is Universitätsklinikum Erlangen. With more than 10,000 highly qualified employe...

Postdoc-Position in Computational Biology to develop multi-omics data integration with the goal to study complex co-morbidities for Parkinson's disease (PD) and inflammatory bowel disease (IBD) at the FAU Erlangen (Germany): www.karriere.uk-erlangen.de/job/postdoct...

Dengue Suppression by Male Wolbachia-Infected Mosquitoes | NEJM Wild-type female Aedes aegypti mosquitoes that mate with male A. aegypti mosquitoes that have been infected with the wAlbB strain of Wolbachia pipientis bacteria produce nonviable offspring owing t...

This is wild! (please excuse pun)

Large, randomized study showing that Wolbachia‑based Aedes mosquito population suppression alone can significantly reduce dengue infections in a real‑world, dense urban setting!

#dengue #IDSky #singapore @nejm.org #MedSky

what sequencing-based strategy do people like to look at CRISPR/cas9 editing in a polyclonal cell population? in the past i have used Sanger+the TIDE algorithm. I know some labs amplify the target region and do NGS- if that option, what company would you use? any other options?

Self-testing for 5 respiratory viruses in adults ≥50 years of age in Germany for longitudinal monitoring of community-acquired acute respiratory infections We aimed to systematically assess acute respiratory infection (ARI) episodes outside medical settings in older adults in Germany to capture real-time, community-based data on incidences, symptoms, hea...

🧪 Adults 50+ in Germany self-tested for 5 respiratory viruses to track community infections. SARS-CoV-2 had highest incidence, RSV caused longer illness & more doctor visits. Real-world insights for public health & vaccination strategies!
www.clinicalmicrobiologyandinfection.org/article/S119...

It cost us > 100 € for six targets and took several weeks. I'm very happy with Novogene for more extensive sequencing projects, but to check CRISPR edits, the other options posted here sound much more effective.

We used Novogene for NGS, did the amplicons ourselves. For some targets TIDE doesnt work although there is a clear KO in NGS and in functional readouts. Dont know why.

Fantastic talk, @j-eyquem.bsky.social - and congrats on the new paper! 1 question: When you do the Nalm6 challenge with your in-vivo CARs (slide at 51m40s), you have a sharp and synchronized drop in BLI at about 13 days after the vector transfer. Does it take that long until the cells are fighting?

Imprinting by influenza virus infection in children can cause a deleterious shift of nearly the entire memory recall response against key, conserved epitopes @nature.com @weillcornell.bsky.social
www.nature.com/articles/s41...

Epstein-Barr Virus Antibodies and Multiple Sclerosis This case-control study investigates if Epstein-Barr virus antibodies can be used to distinguish multiple sclerosis from myelin oligodendrocyte glycoprotein antibody–associated disease and neuromyelit...

Epstein-Barr Virus Antibodies to Differentiate Multiple Sclerosis From Other Neuroinflammatory Diseases

jamanetwork.com/journals/jam...

In this #EditorsChoice, data from The Lund Lab show that CXCR6 promotes the adaptation of T cells as they engage antigen in tissue to increase the probability of survival, memory differentiation, and long-term residence.

🔗 https://ow.ly/6fjA50Yn5zf

HIF-1α+ CD4+ T cells coordinate a tissue-resident immune cell network in the lung A deeper understanding of how tissue-localized immune cells arise and function is critical for developing mucosal vaccines. Currently, there are no mu…

New paper out: HIF-1α+ CD4+ T cells coordinate a tissue-resident immune cell network in the lung
www.sciencedirect.com/science/arti...

Congrats, Carolyn! Looking forward to reading it.

👋 Jesse Mulder, new postdoc in our lab! Jesse completed his undergraduate studies @monashuniversity.bsky.social, Australia. After his Honours year, he investigated the regulation of plasma cell lifespan programming during his PhD in the lab of David Tarlinton. Welcome to www.schoberlab.de/team!

Thanks for highlighting our work!