Targeting IL-1/IRAK1/4 signaling in Acute Myeloid Leukemia Stem Cells Following Treatment and Relapse Therapies for acute myeloid leukemia (AML) face formidable challenges due to relapse, often driven by leukemia stem cells (LSCs). Strategies targeting LSCs hold promise for enhancing outcomes, yet pai...

From the group that previously unveiled large-scale changes in the phenotype and genetic profile of AML LSCs, they are now demonstrating that #IL1RAP is consistently maintained during disease progression.-> 🎯 #CCTx001 🎯 #ADV101
www.biorxiv.org/content/10.1...
#AML #ADC #CellTherapy