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#
Hashtag
#ALKinhibitors
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Signal Transduction and Targeted Therapy
Signal Transduction and Targeted Therapy
@sigtrans-sttt.bsky.social
3 months ago
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#RNase1 activates wild‑type ALK in non‑mutated #NSCLC, driving tumor growth and revealing a novel #oncogenic mechanism, with RDAA‑positive #tumors highly sensitive to FDA‑approved #ALKinhibitors. @mdanderson.bsky.social

#OpenAccess in #STTT: doi.org/10.1038/s413...

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Signal Transduction and Targeted Therapy
Signal Transduction and Targeted Therapy
@sigtrans-sttt.bsky.social
6 months ago
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RDAA, an #oncogenicdriver in non-mutated #NSCLC, demonstrates strong sensitivity to #FDA-approved #ALKinhibitors, highlighting a promising therapy option for patients lacking #TyrosineKinase mutations. @mdanderson.bsky.social

#STTT #OpenAccess: doi.org/10.1038/s413...

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Suzanne Turner
Suzanne Turner
@sdt36suzanne.bsky.social
9 months ago

Really was a fantastic day - we are so humbled to have met you and to have heard about your children’s journeys through #ALCL. We still have so much to do - it is not acceptable that children are still being treated with nasty chemotherapy when there are #ALKinhibitors available. Shame on Pharma!

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