Alt: aerial view of Chicago skyscrapers covered in cloud, with orange to blue sunset colours Credit: Razvan Sera/Amazing Aerial Agency/Science Photo Library

📊 Round up of The Lancet Respiratory Medicine content presented at #SCCM

🏥 Wonderful to see so many advances presented during the congress, continuing progress in #CriticalCare

#ARDS #SEPSIS #BRONCHIOLITIS @sccmcriticalcare.bsky.social

🚨 Conference Alert: New Article Available Open Access @sccmcriticalcare.bsky.social

📊 Bedside identification of subphenotypes in acute respiratory failure (PHIND): a multicentre, observational cohort study

#ARDS #Sepsis #SCCM

🔓 tinyurl.com/mwvtjub3

📰 Linked Comment: tinyurl.com/yy2aps7m

🎥 Don't miss the 𝘀𝗲𝗰𝗼𝗻𝗱 𝗘𝗦𝗜𝗖𝗠–𝗜𝗦𝗖𝗖𝗠 𝗕𝗿𝗶𝗱𝗴𝗲 𝗪𝗲𝗯𝗶𝗻𝗮𝗿 focusing on 𝗔𝗥𝗗𝗦 𝗮𝗻𝗱 𝘁𝗵𝗲 𝗶𝗻𝗷𝘂𝗿𝗲𝗱 𝗹𝘂𝗻𝗴!

💡 Expect a real-life case study, rich clinical insights, and a dynamic expert discussion with our faculty.

🗓️ 𝗧𝗵𝘂𝗿𝘀𝗱𝗮𝘆, 𝟮𝟲 𝗠𝗮𝗿𝗰𝗵, 𝟭𝟲:𝟬𝟬 𝗖𝗘𝗧👉 shorturl.at/yisTe

#ESICM #ISCCM #ARDS #IntensiveCare #ESICMWebinar

🏁 FULLTIME — Dundela 1–1 Ards. Championship

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⏸️ HALFTIME — Dundela 0–1 Ards. Championship

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⚽ KICKOFF — Dundela 0–0 Ards. Championship

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JAMA Network Open presents RCT: Sivelestat and Incidence of Acute Respiratory Distress Syndrome After Cardiovascular Surgery. Population: 210 men, 172 women. Intervention: 424 patients randomized, 382 analyzed. Findings show Sivelestat reduced ARDS compared to placebo.

In patients undergoing cardiovascular surgery with cardiopulmonary bypass, postoperative infusion with #Sivelestat significantly reduced the incidence of #ARDS and 90-day mortality compared with placebo.

ja.ma/3NzsK4q

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⏸️ HALFTIME — Loughgall 0–0 Ards. Championship

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⚽ KICKOFF — Loughgall 0–0 Ards. Championship #loughgall #ards

⚽ KICKOFF — Loughgall 0–0 Ards. Championship

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Pulmonary hemodynamics in #ARDS pts in VV #ECMO
PAH highly prevalent, and early upward trajectories in mPAP predicted mortality
🫁 invasive pulmonary hemodynamic monitoring may provide relevant insights in selected pts at higher risk of RV dysfunction or with early signs of RV failure
🔓 rdcu.be/e7Dof

#ECMO without systemic anticoagulation? Editorial
🔗 bit.ly/4u6yqUd

🩸 Refers to study investigating association between systemic anticoagulation & outcomes in patients with #ARDS receiving VV #ECLS. Authors observed no link between systemic anticoagulation and
short-term survival.
🔗 bit.ly/3P1pkrv

COVID-19 ARDS survivors face lasting disability and high late mortality, researchers report In this single-center ambispective cohort of 283 Polish patients with COVID-19–related ARDS requiring invasive mechanical ventilation, cumulative mortality reached 44.5% at four years after ICU admiss...

😷 Four years after ICU, nearly half of ventilated COVID-19 ARDS patients have died, and survivors still battle fatigue, insomnia, and disability. The long-term toll is stark. www.news-medical.net/news/2026030... #Covid19 #LongCovid #ARDS

VT-109, an EB3 inhibitor, restores endothelial integrity in #ARDS by blocking #CalciumSignaling, reannealing VE-cadherin, and activating #FOXM1; it improves #LungFunction and reduces #inflammation.

#OpenAccess in #STTT: doi.org/10.1038/s413...

ARDS (Acute Respiratory Distress Syndrome): Pathophysiology, Stages, Diagnosis & ICU Management
#ARDS #AcuteRespiratoryDistressSyndrome #CriticalCare #ICU #RespiratoryFailure #MechanicalVentilation #PulmonaryEdema #RefractoryHypoxemia #Sepsis #MedicalEducation

Prone positioning in VV #ECMO?? no net physiological benefit after #ECLS initiation in this animal model 🐖 with severe #ARDS randomized after VV initiation to prone or supine positioning for 48 h, receiving an ultraprotective MV strategy 🫁
Open access #FOAMcc #FOAMecmo
🔓 rdcu.be/e28tP

Prone positioning in VV #ECMO
🐖 8 pigs with severe #ARDS randomized after VV initiation
🫁 PP did not reduce the overall extent/severity of lung injury but shifted distribution of damage, with greater involvement of dependent regions and relative preservation of non-dependent areas.
🔓 rdcu.be/e28tP

Tomorrow we welcome Dr. Angela Meier to Grand Rounds. #MedEd #PCCM #ARDS
@ucsdmedschool.bsky.social

#VT109, a synthetic EB3 inhibitor, shows efficacy in murine #ARDS by restoring endothelial barriers, activating #FOXM1 repair, reducing #inflammation, and improving #LungFunction—emerging as a strong candidate for clinical testing.

#OpenAccess in #STTT: doi.org/10.1038/s413...

🏁 FULLTIME — Ards 0–0 Institute. Championship #ards #institute

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We analyzed serum and genotype data from different time points after sepsis diagnosis and identified 27 significant genetic loci & prioritized 56 genes. Among these, our whole-exome sequencing studies identified PTPRD as a novel #ARDS gene.

In brief, we conducted a proteogenomic approach by leveraging genome-wide association study (GWAS) and multi-trait analyses to assess host genetic factors governing protein levels and uncover novel #ARDS genes.

Protein-based genomic analysis for the identification of risk loci associated with acute respiratory distress syndrome Background Acute respiratory distress syndrome (ARDS) is a life-threatening lung condition that requires admission to an intensive care unit (ICU). Sepsis is one of the leading causes of ARDS and unde...

Identifying host genetic determinants of protein levels in patients with sepsis could also assist in revealing novel #ARDS genes. To evaluate this, we evaluated 10 circulating proteins that may serve as #ARDS biomarkers in a new study (preprint): www.medrxiv.org/content/10.6...

Sepsis-associated acute respiratory distress syndrome in individuals of European ancestry: a genome-wide association study A common variant within the FLT1 gene is associated with sepsis-associated ARDS. Our findings support a role for the vascular endothelial growth factor signalling pathway in ARDS pathogenesis and iden...

There's evidence showing that the genetics of the patient plays a key role in the #ARDS risk. Some of our studies support that. See: www.thelancet.com/journals/lan...

Acute respiratory distress syndrome #ARDS is a critical condition characterized by respiratory failure, an acute inflammatory response, and the development of non-cardiogenic pulmonary edema. Sepsis is one of the leading causes of #ARDS and has a high mortality ICUs.

Dungannon Swifts vs Ards icdb.tv - Internet Commentator Database

Dungannon Swifts vs Ards was on BBC Sport Online (Audio). Coverage presented by Joel Taggart. Co-commentator is Shane McCabe. #DungannonSwifts #Ards #BBCSportOnlineAudio

Dungannon Swifts vs Ards icdb.tv - Internet Commentator Database

Dungannon Swifts vs Ards was on BBC Sounds APP. Coverage presented by Joel Taggart. Co-commentator is Shane McCabe. #DungannonSwifts #Ards #BBCSoundsAPP