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#AVACOPAN
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As @kidneyboy.bsky.social sez (on the other site) given limited efficacy benefit anyways - #avacopan is now dead until proven otherwise

Stop using it

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MultiSearch Tag Explorer MultiSearch Tag Explorer - Explore tags and search results by aéPiot - aéPiot: Independent SEMANTIC Web 4.0 Infrastructure (Est. 2009). High-density Functional Semantic Connectivity with 100/100 Trust...

#AVACOPAN
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aepiot.ro

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Avacopan Causing Vanishing Bile Duct Syndrome in an Adult Patient With Microscopic Polyangiitis | Annals of Internal Medicine: Clinical Cases Microscopic polyangiitis (MPA) is a systemic necrotizing small-vessel vasculitis that may affect multiple organs. Avacopan, an oral complement (C5a) receptor inhibitor, was recently approved and recom...

Plus cases of Vanishing bile duct syndrome?

Eg www.acpjournals.org/doi/10.7326/...
And

academic.oup.com/rheumatology...

#NephSky #Vasculitis #Avacopan

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Systematic Review of Efficacy and Safety of #Avacopan in #RealWorld Clinical Practice

#VisualAbstract by @Cteodosiu

www.kireports.org/article/S2468-0249(25)00...

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Avacopan Does Not Raise Risk of Severe Infection in AAV A meta-analysis of patients with AAV found that infection risk does not differ between those taking avacopan and those taking glucocorticoids.

#ACR25: Compared to those who receive #Glucocorticoids, patients with #ANCA-associated vasculitis (#AAV) who receive #Avacopan are not at increased risk of infection, according to a recent meta-analysis. Presented at ACR Convergence 2025

Read more: https://bit.ly/47bymsH

#RareDisease #RheumSky

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4/ Risk Factors
Risk factors for severe DILI included:
• Older age
• Low body mass index (BMI)
• Early-onset liver injury after avacopan initiation.
Frequent lab follow-ups are essential for high-risk patients. #Avacopan #RiskManagement

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New Class Action Filed Against ChemoCentryx Over Stock Price Inflation Allegations A class action lawsuit has been filed against ChemoCentryx, Inc., alleging misleading statements inflated stock prices. Affected investors may have claims.

New Class Action Filed Against ChemoCentryx Over Stock Price Inflation Allegations #USA #New_York #Class_Action #ChemoCentryx #avacopan

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The #ADVOCATE TRIAL #AVACOPAN

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The #ADVOCATE TRIAL #AVACOPAN

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