As @kidneyboy.bsky.social sez (on the other site) given limited efficacy benefit anyways - #avacopan is now dead until proven otherwise
Stop using it
#AVACOPAN
headlines-world.com/advanced-sea...
aepiot.ro
Plus cases of Vanishing bile duct syndrome?
Eg www.acpjournals.org/doi/10.7326/...
And
academic.oup.com/rheumatology...
#NephSky #Vasculitis #Avacopan
Systematic Review of Efficacy and Safety of #Avacopan in #RealWorld Clinical Practice
#VisualAbstract by @Cteodosiu
www.kireports.org/article/S2468-0249(25)00...
#ACR25: Compared to those who receive #Glucocorticoids, patients with #ANCA-associated vasculitis (#AAV) who receive #Avacopan are not at increased risk of infection, according to a recent meta-analysis. Presented at ACR Convergence 2025
Read more: https://bit.ly/47bymsH
#RareDisease #RheumSky
4/ Risk Factors
Risk factors for severe DILI included:
• Older age
• Low body mass index (BMI)
• Early-onset liver injury after avacopan initiation.
Frequent lab follow-ups are essential for high-risk patients. #Avacopan #RiskManagement
New Class Action Filed Against ChemoCentryx Over Stock Price Inflation Allegations #USA #New_York #Class_Action #ChemoCentryx #avacopan