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New #Robo #Slit antibodies just joined the IPI collections 🧪 Recommended for flow, ICC and IHC, these chimeric #recombinantproteins are specific to human and mouse targets and do not cross-react with other family members.

#axonguidance #neuronalmigration

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Axon Guidance Antibody Collection For neurons to communicate, their axons must navigate precisely to their targets through a complex process known as axon guidance or neuronal migration. This pr

New antibody release!
🧪 Anti-ROBO1 [IPI-ROBO1.81]
🧪 Anti-ROBO3 [IPI-ROBO3.119]
🧪 Anti-ROBO3 [IPI-ROBO3.124]
🧪 Anti-Slit-2 [IPI-Slit2.37]

Use our recombinant monoclonals to study #axonguidance #cellmigration #tissueformation #cytoskelatalorganization, #neuronalwiring & more
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New on bioRxiv! 🧠🧬
Our work uncovers how modularity in the DCC-ECD shapes axon guidance and neuronal migration.Using mouse lines with mutations in Netrin-1 and Draxin binding sites, we show how distinct DCC modules drive precise circuit assembly
#Neuroscience #AxonGuidance #DCC #Netrin1 #Draxin

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AXON2025 Meeting Rotterdam Topics Synaptic plasticity Local translation Neuron-glia interactions Brain development and evolution Human models Single cell profiling Advanced imaging technology And more!

Busy September 17-19? You should be! Join us at #AXON2025 to share research on #synapticplasticity, #braindevelopment, #neuralcircuitry, and more. Early bird registration ends May 1 🦤

#neuroscience #neuroskyence #axonguidance

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Axon Guidance: Explained In the late 19th century, neuroscientist Santiago Ramón y Cajal peered through a microscope at the spinal cords of three-day-old chick embryos and drew

19th century #neuroscientist Santiago Ramón y Cajal peered through a microscope at the #spinalcords of chick embryos and drew what looked like dust mites infiltrating a tomato slice. This moment marked the first step in understanding #axonguidance. Read more 🔬
proteininnovation.org/2025/03/axon...

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Expanding ligand-receptor interaction networks for axon guidance: Structural insights into signal crosstalk and specificity Guidance of nascent axons to their targets is mediated by attractive and repulsive cues that activate receptors on the axonal growth cone.

Our #nervoussystems rely on organized #axonguidance. In a new review paper, IPI and Brown researchers showcase the growing body of #extracellularinteractome studies that evidence new #receptorcomplexes for axon guidance and reveal extensive #signalcrosstalk.

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Axon Guidance: Explained In the late 19th century, neuroscientist Santiago Ramón y Cajal peered through a microscope at the spinal cords of three-day-old chick embryos and drew

Just published: A new review from Rob Meijers, Shaotong Zhu and Alex Jaworski explores the landscape of #ligandreceptor interactions in #axon pathfinding. Get the lay of the land in our #axonguidance explainer 🧠🟦
#neuroskyence #proteinscience
proteininnovation.org/2025/03/axon...

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They have identified a novel role for the EphA4 protein in visual system development. This discovery challenges established theories on #AxonGuidance by demonstrating that, besides repelling axons, the EphA4 receptor can promote adhesion when it binds to ephrinB1.

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Let's unleash the axonal growth cones for this #Fluorescencefriday ! #neuroscience #Liveimaging #microscopy #Axonguidance

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May commissural axons find their way in here 🙏
#Microscopy #LiveImaging #AxonGuidance #Neuroscience

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Always a pleasure to host renowned experts while teaching master courses. Today Dario Bonanomi from @SanRaffaeleMI @ArmeniseHarvard giving a lecture about #axonguidance to #molecularneurobiology students @unipv

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