CRISPR/CasRx-mediated RNA knockdown of β-catenin and Ihh signaling effectively alleviates osteoarthritis.
#CRISPR #CasRx #BetaCatenin #Ihh #Osteoarthritis #RNAEditing #CartilageRepair
www.sciencedirect.com/science/arti...

A new therapeutic strategy for osteoarthritis emerges by targeting the AMPK–β-catenin–Runx2 signaling axis.
#Osteoarthritis #AMPK #BetaCatenin #Runx2 #CartilageDegeneration #OAPathogenesis
doi.org/10.1016/j.ge...

A molecular bridge helps disordered proteins work properly The findings reveal that despite their disordered nature, the protein interactions that drive gene expression are surprisingly modular and even have an underlying organization.

Drs. HC Hodges @hodgeshc.bsky.social, #chanyuensan, K Cermakova @cermakova.bsky.social et al discovered a molecular bridge that facilitates interactions among disordered proteins involved in regulating #geneExpression. #BetaCatenin @bcmhouston.bsky.social #MolecularCell blogs.bcm.edu/2025/07/24/f...

Beta-catenin signaling in jelly combs could slightly differ from what you know.....Bryan Walter @univmiami.bsky.social #PASEDB2025 #Mnemiopsis #celladhesion #betacatenin

#FluorescenceFriday Highlight!
Check out our video showcasing nanobody in vivo to delve into vascular formation and heterogeneity in #zebrafish. 🐟🔬
#Science #Research #BetaCatenin #Nanobody #VascularBiology #Liveimaging