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Excited to see this work on the cover of #MolecularCell. A massive, open #cryoEM #cryoET dataset capturing molecular organization inside intact cells, pushing what’s possible for #visualproteomics, method development, and computational reuse. Congratulations to the authors.
ter.li/of4cgh

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Proud collaboration with the Baker Lab (UW) and Bai Lab (UTSW).
#ProteinDesign #InsulinReceptor #MolecularCell #BiasedAgonism #TranslationalScience

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A quiet ally: a ubiquitin precursor promotes stress resistance and longevity In response to cellular stress, the protein CxUb is activated to identify damaged proteins, thereby maintaining cellular health. The discovery could lead to ways to improve the treatment of cancer and...

👏Congratulations to the #CECAD Cologne's Escobar-Henriques lab and Reichert lab at the @hhu.de for their latest paper in #MolecularCell: a newly discovered #ubiquitin precursor, CxUb, plays a key role in #stress resistance and #longevity.

uni.koeln/7ET86

@unicologne.bsky.social #agingresearch

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A molecular bridge helps disordered proteins work properly The findings reveal that despite their disordered nature, the protein interactions that drive gene expression are surprisingly modular and even have an underlying organization.

Drs. HC Hodges @hodgeshc.bsky.social, #chanyuensan, K Cermakova @cermakova.bsky.social et al discovered a molecular bridge that facilitates interactions among disordered proteins involved in regulating #geneExpression. #BetaCatenin @bcmhouston.bsky.social #MolecularCell blogs.bcm.edu/2025/07/24/f...

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🚨 Check out our latest review in #MolecularCell!

We discuss how formaldehyde, a toxic metabolic by-product, threatens genome stability and disrupts cellular homeostasis.

👏 Outstanding work by our talented PhD Std #MartaValverde @carrerasijc.bsky.social

👉📰
authors.elsevier.com/a/1lDFm3vVUP...

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Cell cycle-dependent mRNA localization in P-bodies - preLights P-bodies are more than just storage sites for translationally repressed mRNAs and RNPs

Two new #postLights are out!

1️⃣ @mohjalloh.bsky.social revisits a #preLight on how mRNA localization to P-bodies depends on the cell cycle—work now published in #MolecularCell.

What’s changed, what held up, and what was added? Read the comparison ⬇️
prelights.biologists.com/highlights/c...

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🚀 Thrilled to share our latest review: "Uracil-induced replication stress drives mutations, genome instability, anti-cancer treatment efficacy, and resistance"

👉 doi.org/10.1016/j.mo...

#CancerResearch #DNARepair #ReplicationStress #MolecularCell #GenomicInstability #CancerTherapy #Uracil

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Really enjoyed reading in #MolecularCell "RNA sensing induced by chromosome missegregation augments anti-tumor immunity"
They found dsRNA sensing is equally important in the #interferon response to micronuclei induced by inhibition of spindle assembly.
www.sciencedirect.com/science/arti...

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I’m thrilled to see my artwork on the #cover of #MolecularCell!
A study by @imilenkovic.bsky.social et al used epitranscriptomic rRNA fingerprinting to identify tissue-of-origin and tumor-specific signatures. @NovoaLab @crg.eu
#sciart #scicomm #science #cancerresearch

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Happy to join this platform with some great news 🥳
Some of my recently published PhD work on active #mTOR at #lysosomes made it to the cover of #MolecularCell!

Thanks to @sofiaahola.bsky.social for the wonderful #SciArt🌏🎈🐦‍🔥

Check out the science behind this art here: www.cell.com/molecular-ce...

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On the cover #MolecularCell. In this issue Acharya and Demetriades show how #mTORC1 🎈activation mediates its own release from the #lysosomes 🪐🌎. It was my pleasure to bring to life the grand idea from Aishwarya and Costas!

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My continued biological education
#LiquidLiquidPhaseSeparation

Phase separation as a new form of regulation in #InnateImmunity

Sensor-Adaptor-Transcription factor-Effector
DNA sensing cGAS-STING-IRF3
RNA sensing PKR
Inflammasome NLRP6

#MolecularCell 2024
www.sciencedirect.com/science/arti...

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(3/3) Their findings were published today in the journal #MolecularCell: doi.org/10.1016/j.mo...
Congratulations to all authors! 👏

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This week's selection of articles and #preprints on #proteostasis thanks to biomed.news -- biomed.news/bims-proteo/...
Highlight: #MolecularCell Subcytoplasmic location of translation controls protein output - www.cell.com/molecular-ce...

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