#Atherosclerosis #FoamCell heterogeneity 2/2

Meta-analysis 37 scRNAseq libraries + 44 scATACseq datasets->
5 Foam cell states

ICAM1+ inflammatory
FOLR2+ phagocytic
MMP9+ matrix-remodeling
ANGPTL4+ hypoxic
COL1A2+ fibroblastic

#Biomol_MDPI 2024
www.mdpi.com/2218-273X/14...

#AngiotensinII #Ferroptosis #EndothelialCell

ANGII➡️⏫CD36➡️⏫Ferroptosis (⏫FerroOrange, ⏫PUFA oxidation ASCL4 LPCAT3 ALOX15 ⏬antioxidant GPX4 SLC7A11 SLC3A2) in HUVEC

CD36 overexpression phenocopies ANGII-induced ferroptosis

#Biomol_MDPI 2024
www.mdpi.com/2218-273X/14...