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#AngiotensinII
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Hao Yin
Hao Yin
@haoyin.bsky.social
3 months ago
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#AngiotensinII #Cardiomyocyte #Ferroptosis #AtrialFibrillation

AAV-expressed GSTP1, GST isoenzyme, rescues ANGII-cardiomyocyte
#LipidPeroxidation
#MitochondrialDysfunction
#Ferroptosis
🫀Fibrosis
Susceptibility to electrical AF

#Europace 2025 @escardio.bsky.social
academic.oup.com/europace/art...

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40:40 Recruitment - celia@4040recruitment.co.uk
40:40 Recruitment - celia@4040recruitment.co.uk
@4040rec.bsky.social
8 months ago
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4TEEN4 begins trial of antibody therapy for cardiogenic shock - PharmaTimes First patient dosed in phase 1b/2a study of procizumab

#4TEEN4 #4TEEN4Pharmaceuticals #antibodytherapy #cardiogenicshock #phase1b/2astudy #procizumab #monoclonalantibody #PROCARD1trial #circulatingdipeptidylpeptidase3 #cDPP3 #cardiacdepressionfactor #shock #cDPP3inhibitor #angiotensinII #PROCARD1study
pharmatimes.com/news/4teen4-...

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Hao Yin
Hao Yin
@haoyin.bsky.social
8 months ago
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#AngiotensinII #Ferroptosis #EndothelialCell

ANGII➡️⏫CD36➡️⏫Ferroptosis (⏫FerroOrange, ⏫PUFA oxidation ASCL4 LPCAT3 ALOX15 ⏬antioxidant GPX4 SLC7A11 SLC3A2) in HUVEC

CD36 overexpression phenocopies ANGII-induced ferroptosis

#Biomol_MDPI 2024
www.mdpi.com/2218-273X/14...

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Hao Yin
Hao Yin
@haoyin.bsky.social
2 years ago
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#SIRT6 transgenic overexpression⏬#AbdominalAorticAneurysm in Apoe-/-🐭+ #AngiotensinII

AAA endpoints rescued by Sirt6 OE->
⏫p21, but not p16 (which cells?)
⏫Mɸ or neoangiogensis

A possible SIRT6 role in #SmoothMuscleCell #Senescence SASP

#Atherosclerosis 2024
www.sciencedirect.com/science/arti...

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Johannes Gutenberg-Universität Mainz
Johannes Gutenberg-Universität Mainz
@unimainz.bsky.social
5 years ago
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Neue Erkenntnisse zur Früherkennung von #GrünerStar: Gewebshormon #AngiotensinII spielt wichtige Rolle bei der Entstehung der tückischen #Augenkrankheit...

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