#AngiotensinII #Cardiomyocyte #Ferroptosis #AtrialFibrillation

AAV-expressed GSTP1, GST isoenzyme, rescues ANGII-cardiomyocyte
#LipidPeroxidation
#MitochondrialDysfunction
#Ferroptosis
🫀Fibrosis
Susceptibility to electrical AF

#Europace 2025 @escardio.bsky.social
academic.oup.com/europace/art...

Current and Potential Roles of Ferroptosis in Bladder Cancer

Researchers summarize how iron-dependent #LipidPeroxidation drives #ferroptosis, outline the metabolic and signaling pathways regulating ferroptosis in #BladderCancer, and highlight emerging ferroptosis inducers and combination strategies.

#OpenAccess: doi.org/10.1007/s115...

A newly identified ferroptosis regulator controls lipid peroxidation through NRF2-dependent transcription, revealing a key vulnerability in cancer cell death pathways.
#Ferroptosis #NRF2 #LipidPeroxidation #RedoxBiology
www.nature.com/articles/s41...

This new research highlights that #MaternalInfection alters metabolism and mitochondrial activity in the developing #Heart, with #OxidativeStress and #LipidPeroxidation driving dysfunction. #medsky

#OpenAccess: www.sciencedirect.com/science/arti...

Recent review on #Ferroptosis offers new strategies to reverse #DrugResistance in DigestiveCancers through #GPX4 pathways, #IronMetabolism, and #LipidPeroxidation, paving the way for targeted and combination therapies. #medsky

#OpenAccess: www.sciencedirect.com/science/arti...

Polyunsaturated fatty acid-induced metabolic exhaustion and ferroptosis impair the anti-tumour function of MAIT cells in MASLD Mucosal-associated invariant T (MAIT) cells constitute a highly abundant innate-like T cell population in the human liver that is critical for immune surveillance of hepatic cancers but often dysfunct...

9/ 📖 Read more: www.journal-of-hepatology.eu/article/S016...

@easlnews.bsky.social @jhepatology.bsky.social @cd1mr1.bsky.social
#Immunometabolism #MAITcells #LiverImmunology #Ferroptosis #MASLD #HCC #LipidPeroxidation #TcellDysfunction #CancerImmunotherapy #TumorMicroenvironment #FattyLiver

Adult #SmoothMuscleCell #TransferrinReceptor1 KO 🐭+ 1 ANGII or 2 DOCA salt
⏬ #AorticDilation
⏬Medial thickening
⏬Elastin breaks
⏬4HNE #LipidPeroxidation
⏬Ferritin Not divalent metal transporter 1
↔️blood pressure

#HypertensRes 2025
www.nature.com/articles/s41...

Online now - the Review "The metabolic code of #ferroptosis: nutritional regulators of cell death" from @angelifriedmann.bsky.social @k-hadian.bsky.social and colleagues.

#LipidPeroxidation #Nutrients #Metabolites #Vitamins #Lipids

Read it here 👉 authors.elsevier.com/sd/article/S...

Iron-dependent lysosomal LDL oxidation induces the expression of scavenger receptor A in human THP-1 monocytes

➡️ buff.ly/2iDCL7m

#Atherosclerosis #Ferritinophagy #LipidPeroxidation #Lysosome

This review provides a detailed overview of #Ferroptosis characteristics and the mechanisms that allow #CancerStemCells to evade it, emphasizing its potential as an innovative cancer treatment strategy. #LipidPeroxidation #IronMetabolism #medsky

#OpenAccess: www.sciencedirect.com/science/arti...

#OxidativeStress #LipidPeroxidation #Omega3 #lcl6 #MentalHealth

Lung #Pericyte #Ferroptosis #Sepsis

A pro-ferroptotic axis
#YAP ACSL4 ⏫PUFA esterification ⏫Phospholipids for #LipidPeroxidation

1⃣Fer-1
2⃣Pericyte Acsl4 KO
3⃣NG2/CD13-targeting LNP to deliver ad-shACSL4
⏬🫁 pericyte loss
⏫Survival
in CLP septic🐭

#RedoxBiol 2024
www.sciencedirect.com/science/arti...

Interesting link between high glucose in T2D patients and impaired T cells responses towards virus.

#LipidPeroxidation
#TcellSignalling
#T2D

Hyperglycemia-triggered lipid peroxidation destabilizes STAT4 and impairs anti-viral Th1 responses in type 2 diabetes

www.sciencedirect.com/science/arti...