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Evaluating the Causal Relationship Between Carnitine-Related Metabolites and Breast Cancer: A Mendelian Randomization and Transcriptomic Analysis Introduction: Breast cancer (BC) is the most common malignancy among women worldwide. Although observational studies have linked carnitine-related metabolites (CRMs) to BC, causal inference has been ...

#mendelianrandomization #breastcancer #creatinine #metabolites

www.archivesofmedicalscience.com/Evaluating-t...

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Decoding the chemical messengers: Gut microbes talk to the whole body through metabolites Microbial metabolites influence health far beyond the intestinal tract. Yet, a systematic understanding of how these molecules precisely control specific immune cell functions and regulate disease…

#Gut #microbes talk to the whole body through #metabolites ...

| #bacteria | #microbiology | #cancer | #microbial | Via @eurekalert.bsky.social

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📝 Now online - the Review "Molecular and structural mechanisms of nutrient sensing in the mTORC1 pathway" from @robzonculab.bsky.social and co.

#mTORC1 #PrimaryNutrientSensor #AminoAcidSensor #CholesterolSensor #Metabolites

Read it here: authors.elsevier.com/a/1mrsu_M0e4...

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#MPB
Optimized mix of calcium, phenobarbital, methyl jasmonate & 5-azacytidine boosts ganoderic acid yield in Ganoderma lucidum by 48%.
Details: maxapress.com/article/doi/10.48130/mpb...
#Ganoderma #Metabolites

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(2) Maria Correia studied the effects of #microbiota produced #metabolites, particularly short-chained fatty acids (butyrate) on #mitochondria, whole animal #metabolism and cold tolerance, via experimental supplement. Massive amount of data collected, super well done!

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Molecular insights into volatile organic compound sensing and signaling in plants Plants interpret important environmental cues through their perception of volatile organic compounds (VOCs), yet the molecular mechanisms enabling this process remain poorly understood. This review p....

[📰 Paper] Molecular insights into volatile organic compound sensing and signaling in plants

Read the article: onlinelibrary.wiley.com/doi/10.1111/...

@vocspop.bsky.social

#plantscience #plantbiology #chemicalecology #metabolites #VOC #karrikin #plantinteractions #research #openscience

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Heart disease risk tied to certain gut microbial metabolites – BioNews Central In a study involving data from thousands of people, the risk of a new coronary heart disease diagnosis was statistically associated with the bloodstream levels of nine specific metabolites produced by gut microbes. ...

In a study involving data from thousands of people, the risk of a new #CoronaryHeartDisease diagnosis was statistically associated with the bloodstream levels of nine specific #metabolites produced by #GutMicrobes
#HeartDiseaseRisk #CardiovascularRisk #GutMicrobiome #Metabolomics

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New #Publication on "#Degradation of #Toxins and #Metabolites of #Cyanobacteria and #Micropollutants during #Biological Sand #Filtration"
by Valentin Rougé, Urs von Gunten, Anne Dax, Oliver Köster from Eawag and Water works Zürich! doi.org/10.1021/acs....

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No Impairment in Driving Despite Residual THC Blood Levels 12-15 hours after last cannabis use

"“Neither blood nor oral fluid THC, CBD, or metabolites was significantly correlated with any measure of driving,” the study’s authors concluded."
#MedicalMarijuana #MedicalCannabis #Marijuana #Cannabis #Driving #Performance #THC #CBD #Metabolites @normlorg.bsky.social

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Microbiome Metabolism and Metabolites: Discovery and Function in Health and Disease | Keystone Symposia Join us at the Keystone Symposia on Microbiome Metabolism and Metabolites: Discovery and Function in Health and Disease, January 2026, in Banff, with field leaders!

Did you miss January's @keystoneSymposia.bsky.social #Microbiome Metabolism & #Metabolites? You can still register for On Demand Access to all of the talks:
hubs.la/Q03TCgfj0 #KSMicroMetab26

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Oral–systemic links: periodontal microbes and the blood-brain barrier at Queen Mary University of London on FindAPhD.com PhD Project - Oral–systemic links: periodontal microbes and the blood-brain barrier at Queen Mary University of London, listed on FindAPhD.com

🧠 🧪#PhDOpportunity

Could oral #microbes influence #brain health?

This PhD investigates how periodontal microbial #metabolites interact with the #blood–brain barrier and affect neurovascular biology.

📍 @qmul.bsky.social
👨🏻‍🔬 @drsimonmcarthur.bsky.social
www.findaphd.com/phds/project...

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Explore the BCCM/LMG bacterial strains from Antarctic origin

- Subcollection of 306 well-documented strains
- Isolated from a variety of natural sources (glacier, fumaroles, microbial mats,…)
- >80 different genera
- Potential resources of specialized #metabolites

bccm.belspo.be/LMG-Antarcti...

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#Metabolites associated with #endophytic fungi in #agarwood: #fungal compounds and #host metabolites #triggered by fungi
doi.org/10.1080/2150...
@tandfresearch.bsky.social

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Metabolomics goes beyond genomics-capturing environmental, microbial & drug‑related biology in one readout. By measuring endogenous + exogenous #metabolites, it reveals how exposures shape disease.
See more use cases: lnkd.in/gd8Ahazf

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Figure 9: Anti-influenza mechanism of action of cis-aco. DOI: 10.1038/s44321-026-00379-8.

Figure 9: Anti-influenza mechanism of action of cis-aco. DOI: 10.1038/s44321-026-00379-8.

📢Last weeks #immunometabolism discoveries 🧪@Bims_BiomedNews ⬇️⬇️⬇️

biomed.news/bims-imicid/...

Interesting finding:

Cis-aconitate therapy protects against influenza mortality by dual targeting of viral polymerase and ERK/AKT/NF-κB signaling #mitochondria #metabolites

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The hidden role of amino acids and secondary metabolites in plant drought tolerance Drought stress (DS) severely threatens global crop productivity by disrupting key physiological, biochemical, and metabolic processes during plant dev…

The hidden role of #amino acids and secondary #metabolites in plant #drought tolerance

www.sciencedirect.com/science/arti...

#PlantScience #StressTolerance @plantsciencedbg.bsky.social @plantsciencedbg.bsky.social @plantbiology.bsky.social @plantstress.bsky.social @plantmetabolism.bsky.social

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Experimental set-up. 3 to 5-day-old virgin flies were collected and separated into groups of ten by sex, using ten vials of ten flies per sex/genotype/treatment combination. Flies in the exercise-treated group underwent five consecutive days of exercise using the Treadwheel, while animals in the control group were handled the same way, but without the treatment on the Treadwheel. 1 day after completing the exercise treatment, climbing ability of all animals was measured. At this point, the animals were weighed and frozen for metabolite analysis.

Experimental set-up. 3 to 5-day-old virgin flies were collected and separated into groups of ten by sex, using ten vials of ten flies per sex/genotype/treatment combination. Flies in the exercise-treated group underwent five consecutive days of exercise using the Treadwheel, while animals in the control group were handled the same way, but without the treatment on the Treadwheel. 1 day after completing the exercise treatment, climbing ability of all animals was measured. At this point, the animals were weighed and frozen for metabolite analysis.

James Walts & co use #Drosophila melanogaster to investigate how exercise impacts body composition, specifically, protein content. doi.org/10.1242/bio....

#ExercisePhysiology #Metabolites #TreadWheel #GWAS

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Thrilled to share our new review, now published in Ageing Research Reviews.

Here we synthesize evidence showing how gut microbiota-derived #metabolites act as central regulators of immune #aging, linking #dysbiosis to #inflammaging and age-related diseases.

www.sciencedirect.com/science/arti...

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#Goo:
#Experiments show some #sponges can #survive 100 times the #lethal #radiation #dose for #humans without #developing #cancer. They #achieve this by #overexpressing #genes for #DNA #repair & #signaling: rather than use an #immune #system to #kill #mutant #cells, they #yield #metabolites.
#vss365

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We are pleased to announce the appointment of Dr. Xiaoxiao Ma as the new Section Editor-in-Chief of the Section “Lipid Metabolism” in Metabolites MDPI (ISSN: 2218-1989).

See the full interview: buff.ly/eKwFt4R

#MDPI #OpenAccess #Metabolites #Research

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CellDrop Automated Cell Counter: Count Cells Without Slides Reduce costs and streamline your cell counting workflows with the DeNovix CellDrop Automated Cell Counter.

A breath of #air could help diagnose #gut #microbiome disruptions ...

| #VolatileOrganicCompounds | #VOC | #microbes | #biomarkers | #colon | #metabolites | Via the-scientist .com

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Phylogeny-Aware Metabologenomics Accurately Assigns Natural Products to Biosynthetic Gene Clusters
#microbiology #biotechnology #metabolites #MicroSky
doi.org/10.1111/1751...

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#JJC2026 Laure Bardiot (@inrae-bioger.bsky.social) on specialized #metabolites in the infectious process of #phytopathogenic #fungi

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We are looking forward to the LED3 Lecture of Anne Osbourn on January 29th She will talk about "Harnessing plant metabolic diversity for food and health applications".

If you are interested, make sure to come by!

www.universiteitleiden.nl/en/science/l...

#ChemBio #ChemSky #Plants #Metabolites

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Scientists Extract Metabolic Molecules From Million-Year-Old Fossils for the First Time

Scientists Extract Metabolic Molecules From Million-Year-Old Fossils for the First Time

Scientists Extract Metabolic Molecules From Million-Year-Old Fossils for the First Time
#evolutionsoup #evolution #Metabolites #science #fossils
👇🏿👇🏽
is.gd/1iZT96

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The team revealed that pharmacological inhibition of SAM and FBP1 in-vitro reduce virus infection at later stages. Revealing, for the first time, that CNS #metabolites not only differ between meningitis and encephalitis associated with TBEV, but also influence TBEV lifecycle.

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Thank you @mmzdouc.bsky.social for detailing our work!
In this study we highlight conserved & unique #clusters and link 5 #lichen #metabolites to #BGCs.
Thank you @marnixmedema.bsky.social & all the collaborators 🥂!
#PKSs #RiPPs #secondaryMetabolism #depsides #fungi #MS #omics

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Elevated Levels of Pesticides, Known Nervous System Poisons, During Pregnancy Tied Directly to Diet - Beyond Pesticides Daily News Blog Maternal exposure through diet to organophosphate pesticides (OP) increases health risks, as shown in a study of OP metabolites.

New study finds peak #concentrations of #organophosphate #pesticide #metabolites in the urine of #pregnant mothers 6-12 hours after consuming contaminated fruits and vegetables. #OHRI #HealthCanada➡️ Blog: https://ow.ly/L9q550XMMzb

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#Genetic #engineering advances targeting #amino acids and secondary #metabolites biosynthesis for enhanced #drought tolerance

www.sciencedirect.com/science/arti...

#CRISPR #PlantScience @eusynbios.org @crisprmeeting.bsky.social @sicb.bsky.social @jipb.bsky.social @plantmetabolism.bsky.social

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#Crosstalk between #amino acids, secondary #metabolites, and other plant #growth regulators under #drought

www.sciencedirect.com/science/arti...

#PlantScience #Botany @botsocamerica.bsky.social @ashs-hort.bsky.social @botany.one @bsbibotany.bsky.social @ejbotany.bsky.social @sebiology.bsky.social

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