Advancing cystic fibrosis treatment: investigational agents on the horizon Cystic fibrosis (CF) treatment has been transformed by CF transmembrane conductance regulator (CFTR) modulator therapies, yet significant gaps remain for those with non-responsive or modestly respo...

Our new paper has been published: "Advancing cystic fibrosis treatment:
investigational agents on the horizon"
in Expert Opinion in Pharmacotherapy 👨‍🔬🧬🔬🧫 💊

#cysticfibrosis #CFTR #CFTRmodulator #noveltherapeutics #precisionmedicine #pharmacology #genetherapy

www.tandfonline.com/doi/full/10....

Recent developments in cystic fibrosis drug discovery: where are we today? The advent of variant-specific disease-modifying drugs into clinical practice has provided remarkable benefits for people with cystic fibrosis (PwCF), a multi-organ life-limiting inherited disease....

Our new paper has been published: "Recent developments in cystic fibrosis drug discovery: where are we today?"
in Expert Opinion in Drug Discovery Taylor & Francis 👨‍🔬🧬🔬🧫 💊

#cysticfibrosis #CFTR #CFTRmodulator #noveltherapeutics #precisionmedicine
#multiomics

www.tandfonline.com/eprint/RNWZS...

Sage Journals: Discover world-class research Subscription and open access journals from Sage, the world's leading independent academic publisher.

Our new paper has been published: "Cystic fibrosis: new challenges and perspectives beyond elexacaftor/tezacaftor/ivacaftor" in Therapeutic Advances in Respiratory Disease 👨‍🔬🧬🔬🧫 💊
#cysticfibrosis #CFTR #CFTRmodulator #noveltherapeutics #precisionmedicine

journals.sagepub.com/doi/10.1177/...

Rescue of Mutant CFTR Channel Activity by Investigational Co-Potentiator Therapy Background: The potentiator VX-770 (ivacaftor) has been approved as a monotherapy for over 95 cystic fibrosis (CF)-causing variants associated with gating/conductance defects of the CF transmembrane c...

Our new paper has been published: "Rescue of Mutant CFTR Channel Activity by Investigational Co-Potentiator Therapy" in Biomedicines 👨‍🔬🧬🔬🧫 💊
#cysticfibrosis #drugdevelopment #cftrmodulator #precisionmedicine

@emory-choa-cfair.bsky.social

www.mdpi.com/3116446

Redirecting

Our new paper has been published: "Direct access of 4-acyl-1,2,3-triazoles from acetophenones: A synthetic shortcut for novel p.Phe508del-CFTR traffic correctors" in Journal of Molecular Structure 👨‍🔬🧬🔬🧫 💊
#cysticfibrosis #drugdevelopment #cftrmodulator

doi.org/10.1016/j.mo...