Scientists have discovered two previously unknown subtypes of human basophils 🎉 The first comprehensive single-cell map 🧬 of these cells is now an open resource 🖥️ for understanding diseases like allergies 🤧
#Immunology #allergy #singlecellbiology #CITEseq

🔗 ino.to/qtQM0SI

ADTnorm: robust integration of single-cell protein measurement across CITE-seq datasets - Nature Communications Here the authors present a computational method that expands the potential of multimodal single-cell analyses by delivering an accurate, fast, and user-friendly approach for normalizing and comparing ...

Our collaborators @rgottardo.bsky.social Peter Sims and Ken Stuart (and others) develop tool ADTNorm, a method of helping noisy CITE-seq data to be "normalized"
#antibody
#ImmuneSky

nature.com/articles/s41...

#CITEseq #SingleCell #ADTNorm

ADTnorm: robust integration of single-cell protein measurement across CITE-seq datasets - Nature Communications Here the authors present a computational method that expands the potential of multimodal single-cell analyses by delivering an accurate, fast, and user-friendly approach for normalizing and comparing ...

🧬 New paper out!
🔗 www.nature.com/articles/s41...

Frustrated by noisy CITE-seq data?
ADTNorm helps normalize it and introduces a staining index to assess antibody quality.

Great work by former postdoc Ye Zheng. Supported by @hipcproject.bsky.social

#CITEseq #SingleCell #ADTNorm

🌟The first report of GOLM1 protein-level profiling at single-cell resolution.🌟

Learn more about the Human Discovery Panel here: www.ptglab.com/products/Mul...

#Multiomics #SingleCell #BiomarkerDiscovery #CITEseq #HumanDiscoveryPanel

Jun 2024
First data release of ImmGenT!(cbdm.connect.hms.harvard.edu/ImmgenT/Publ...). Over 30 labs to profile every mouse T cell / location / state.
In collaboration with BioLegend. The dedicated browser is developed by Dania, Niket, and Brinda. #CITEseq #TCR-V #immgen #singleCell

Immune checkpoint landscape of human atherosclerosis and influence of cardiometabolic factors Nature Cardiovascular Research - Barcia Durán, Dayasagar, et al. map the expression of immune checkpoints in human atherosclerosis and examine the influence of lipid-lowering treatments and...

Excited to share my Co-First author paper describing ICI landscape of human atherosclerosis plaque &CCR7+ FSCN1+ DCs as crucial Immune-checkpoint-hub. @chiaragiannare1 @kathrynmoorelab@NYULH_DepofMed #Immunology#CyTOF #CITEseq #spatialproteomics #scRNAseq #atherosclerosis #ICIs #cancer rdcu.be/d1S6b

(3/7) First, we followed up on our paradigm-shifting findings in @cellcellpress.bsky.social
(tinyurl.com/52u5fsfk) by diving deep into the age-unique platelet specification pathway (#megakaryopoiesis) using #CITEseq and a number of other approaches...