Today, in #preprinthub2 @alisaiakupova.bsky.social @mdc-berlin.bsky.social will present a #preprint from Katya Koltsova lab (Cedars-Sinai Medical Center) on how IL-17RC signaling connects intestinal #microbiota and #neuroimmune interactions in #atherosclerosis 🍔🦠🐭

www.biorxiv.org/content/10.6...

Evolocumab for Patients Without Known Atherosclerosis and With Diabetes This prespecified subgroup analysis of the VESALIUS-CV multinational randomized clinical trial assesses whether evolocumab could prevent a first major cardiovascular event in adult patients without kn...

En pacientes de alto riesgo sin aterosclerosis significativa conocida con diabetes, evolocumab reduce el riesgo de un primer evento CV mayor #evolocumab #diabetes #atherosclerosis jamanetwork.com/journals/jam...

A nature-inspired #Biomimetic confined cascade enzyme #Nanoreactor scavenges ROS, targets atherosclerotic plaques, and reduces inflammation & cellular senescence, offering a promising strategy against #Atherosclerosis.
#STTT #OpenAccess: doi.org/10.1038/s413...

Mechanism of THSWD regulating NF-κB signaling pathway in the treatment of AS.

💊 Can TCM target atherosclerosis at multiple levels? 🧪

THSWD modulates key pathways (NF-κB, PI3K/AKT, MAPK, mTOR), reduces inflammation, and improves vascular function.

A systems-level approach to cardiovascular therapy.

🔗 Read full study:
doi.org/10.1016/S187...

#Atherosclerosis #TCM #CJNM

Evolocumab for Patients Without Known Atherosclerosis and With Diabetes This prespecified subgroup analysis of the VESALIUS-CV multinational randomized clinical trial assesses whether evolocumab could prevent a first major cardiovascular event in adult patients without kn...

En pacientes de alto riesgo sin aterosclerosis significativa conocida y con diabetes, evolocumab reduce el riesgo de un primer evento CV mayor #evolocumab #atherosclerosis #diabetes jamanetwork.com/journals/jam...

#seminar on April 9 at noon by Coraline Héron from @parcc-inserm.bsky.social : Impact of Intermittent Hyperglycemia on #Inflammation, Gut #Microbiota, and #Atherosclerosis
institutcochin.fr/en/agenda/im...
@parispostdocs.bsky.social

The Blood Pressure Paradox: Why Lowering Your Numbers Could Be Dangerous In today's episode we're uncovering the "Blood Pressure Paradox" and why the modern medical push for ever-lower targets may actually be doing more harm than good. We explore how shifting guidelines have turned nearly half of all American adults into "hypertensive" patients overnight, often based on variable or incorrect measurements. You will learn why high blood pressure may actually be a vital compensatory response to maintain blood flow to the brain and kidneys rather than a primary disease. We also dive into the hidden risks of over-medication, including increased mortality, falls, and kidney injury,. References: - https://www.forgottenmedicine.com/p/understanding-blood-pressure-in-a-healthy-way - https://www.forgottenmedicine.com/ Support our work. Make a small donation. Support our work. Make a small donation. This removes any advertisements and help us continue bringing more interesting topics and confronting mainstream narrative on health. Click the Link to support us:https://www.spreaker.com/podcast/foodnourish-deep-dives--6602003/support

📣 New Podcast! "The Blood Pressure Paradox: Why Lowering Your Numbers Could Be Dangerous" on @Spreaker #arteries #atherosclerosis #blood #cardiology #circulation #diuretics #doctors #guidelines #health #hypertension #longevity #medicine #nutrition #pharmaceuticals #pressure #research #safety

#Atherosclerosis

DNA sensor TLR9 KO in Apoe-/-🐭➡️
⏬Lesional calcification, Alkaline phosphatase & BMP2
↔️Plasma lipid

ODN1826, TLR9 agonist➡️
⏫BMP2 RANKL in Mφ, Not Smooth Muscle Cell

Conditioned medium of ODN1826-treated Mφ➡️
⏫SMC BMP2 RANKL

Heart Vessels 2025
link.springer.com/article/10.1...

2/2 "This, in turn, is one of the leading causes of #atherosclerosis, which is the medical term for 'clogged arteries.'"

Statins Combined with AAV8-TBG-LOX-1 Reduce the Vascular Lipid-driven Inflammatory Response and Inhibit Atherosclerosis

This study shows that combining statins with #AAV8 TBG #LOX1 holds promise for reducing lipid-driven #Inflammation, limiting #Macrophage deposition & inhibiting #Atherosclerosis, offering a new target for treatment in #CardiovascularDisease. #medsky
Read: doi.org/10.1007/s115...

A nature-inspired confined cascade enzyme #Nanoreactor integrating multiple #Nanozyme activities within a #Biomimetic platform modulates inflammatory plaque microenvironments and inhibits #FoamCell formation in #Atherosclerosis.

#STTT #OpenAccess: doi.org/10.1038/s413...

Benzo[a]pyrene (BaP) worsens atherosclerosis via SPP1-driven macrophage inflammation and lipid dysregulation. Integrative omics with cellular validation reveal SPP1 as a potential target in pollution-related vascular disease. #Atherosclerosis #EnvironmentalHealth #SPP1
doi.org/10.1016/j.vp...

Single-cell analyses reveal #VascularEndothelialCells act as non-professional #phagocytes in #Atherosclerosis, where #SRB1 drives apoptotic debris uptake via #adherensjunction and cytoskeleton remodeling, uncovering a novel clearance pathway.

#OpenAccess: doi.org/10.1016/j.ge...

Just out.

Genetically determined ancestry is associated with different plaque morphology and molecular features.

In collaboration with @clintomics.bsky.social. @eassociety.bsky.social @umcutrecht.bsky.social #uva #plaque #atherosclerosis #GWAS #GeneSky doi.org/10.1016/j.at...

🧬New from Li et al!
📄Epigenome-Wide Association Study of Blood Proteome in the #Atherosclerosis Risk in Communities Study
#EWAS #methylation
👉 bit.ly/4l5hgSu

Screen all kids between 2 and 10 for high cholesterol, pediatric society recommends TORONTO - The Canadian Paediatric Society is recommending cholesterol screening for all kids between two and 10 years old.

#cdnhealth Screen all kids between 2 and 10 for high cholesterol, pediatric society recommends. Statement says #atherosclerosis or plaque buildup in the arteries, including cholesterol — starts in childhood and is a key driver of heart disease and stroke. www.thecanadianpressnews.ca/national/scr...

Why Crash Dieting Is Hurting Your Heart | Medical News Bulletin You might have heard that Yo-yo dieting makes you more vulnerable to heart disease, but why is that? Scientists say they might have an answer.

Yesterday I reported on a study that highlighted the links between cardiometabolic health, overloaded fat storage and inflammation. This link goes deep and shows up in surprising ways! medicalnewsbulletin.com/yo-yo-diet-h... 🧪 🩺 ⑂ lipidtime medsky #metabolichealth #atherosclerosis #weightloss

Association between absolute blood eosinophil count and carotid plaque and coronary artery calcification in the Multi-Ethnic Study of Atherosclerosis (MESA) In a large, ethnically diverse US population, blood eosinophil count was associated with carotid arterial plaque and coronary artery calcium presence and s

The February 2026 issue of #JLB kicks off with "Association between absolute blood #Eosinophil count and #CarotidPlaque and #CoronaryArtery calcification in the Multi-Ethnic Study of #Atherosclerosis (MESA)" by Nyla Mathis, Mats Johansson and colleagues @uw-medicine.bsky.social

Polygenic risk score & subclinical atherosclerosis 🧬
A new study finds that polygenic risk scores predict subclinical atherosclerosis in first-degree relatives of patients with premature coronary artery disease.
👉 https://ow.ly/MHWK50YfqQV

#Genetics #Atherosclerosis #CardioRisk

Published in Precision Clinical Medicine, the study demonstrates that interferon regulatory factor 7 (IRF7) drives smooth muscle cells to transform into inflammatory, macrophage-like cells within arterial plaques.
#Phenotype switching #Atherosclerosis
Details: doi.org/10.1093/pcme...

#FoodAsMedicine #Nutrition
#Calcium #Atherosclerosis
#VitaminD + #VitaminK2
#BoneHealth + #HeartHealth
#MK7 #Natto #Sauerkraut
m.youtube.com/watch?v=Bn_p...

Association between atherogenic index of plasma and various metabolic conditions: an umbrella review on meta-analyses - BMC Cardiovascular Disorders Background and objective The Atherogenic Index of Plasma (AIP) is increasingly recognized as a key indicator of lipid disturbances and an important predictor of cardiovascular disease (CVD) risk. Due ...

The Atherogenic Index of Plasma (AIP) shows strong links with CAD, MI, MetS, T2DM & OSA, but not with stroke, all-cause mortality, or NAFLD. AIP may be a useful, low-cost biomarker for cardiometabolic risk assessment. #Metabolism #Atherosclerosis link.springer.com/article/10.1...

#Diet #FoodAsMedicine #HeartHealth
#ReverseCholesterolTransport
#NitricOxide
Reverse #Atherosclerosis

m.youtube.com/watch?v=q2Zj...

You #Satanic quack. We see the Evil pushing through to you face! Your demonic nature is literally breaking through. This so-called #FoodPyramid flies in the face of experiment and medical science. It will benefit for-profit cath labs (all are) and cause #atherosclerosis deaths to increase.

New article:
This study reveals that EndMT contributes to atherosclerosis by generating osteogenic- and chondrogenic-like cells, linking endothelial dysfunction to vascular calcification in disease
#EndMT #Atherosclerosis #VascularBiology #CardiovascularScience
doi.org/10.1016/j.vp...

Check The Full Video - https://youtu.be/_yyKQm5cj4Y

Aortic Atherosclerosis: A Silent Condition That Threatens Heart Health | Medickpidia | #aorticatherosclerosis #atherosclerosis #hearthealth #cardiovasculardisease #arteryhealth #heartdiseaseawareness

#PulsedElectroMagneticFields inhibit #NLRP3 #inflammasome activation, reduce endothelial inflammation and #pyroptosis, restore mitochondrial function via TRPV4 regulation, and delay #atherosclerosis progression, unveiling a mechanobiological pathway.

#STTT: doi.org/10.1038/s413...

Australian Researchers Develop Nanoparticles to Combat Arterial Plaque and Prevent Heart Attacks Heart disease remains the leading cause of death worldwide. In most cases, atherosclerosis drives this risk by causing fatty plaques to build up inside arteries. These plaques can trigger heart attacks and strokes. Now, Australian researchers report a promising breakthrough: arterial plaque nanoparticles designed to detect plaque, reduce inflammation, and remove harmful cholesterol from artery walls. This technology could reshape how doctors manage and prevent…

Australian scientists have developed arterial plaque nanoparticles that can detect inflamed plaques, reduce inflammation, and remove harmful cholesterol from artery walls all in one approach.

#HeartDisease #Nanotechnology #CardiovascularHealth #Atherosclerosis #MedicalResearch #HealthScience

📊𝐍𝐞𝐰 𝐈𝐧𝐟𝐨𝐠𝐫𝐚𝐩𝐡𝐢𝐜! Current Insights into Antithrombotic Therapies for Ischemic Stroke Prevention - Focus on Atherosclerotic Stroke Disease

𝐄𝐗𝐏𝐋𝐎𝐑𝐄 the full infographic here: world-stroke-academy.org/news/current...

#StrokeEducation #StrokePrevention #Atherosclerosis

WP2 | Antibody fragment selection for atherosclerosis

Partners: UBx (Lead), MAbS, MUMC, IMGT
#Atherosclerosis #EUproject #ABCardionostics