Case Series of Histopathological Findings in Chronic Kidney Disease: Insights From the Kidney Precision Medicine Project The Kidney Precision Medicine Project is obtaining kidney biopsies from people with chronic kidney disease (CKD) and acute kidney injury for comprehensive clinical, histopathological, and molecular ch...

Resurfacing the two latest #KPMP publications for you to read this week 📚

#CJASN #KidneyMedicine #CKD #Protein #Histopathology #Imaging #Research #NewScience

@asnpublications.bsky.social

www.kidneymedicinejournal.org/article/S259...

journals.lww.com/cjasn/abstra...

#KPMP investigators are starting off 2026 strong with exciting new publications 💪

"Refining the Composition and Significance of Human Kidney Intratubular Casts Using Spatial Protein Imaging" published online yesterday in #CJASN by Nanamatsu, El-Achkar and team

journals.lww.com/cjasn/abstra...

Complement Profiling in Glomerular Disease: Insights from Laser Microdissection and Mass Spectrometry #CJASN journals.lww.com/cjasn/abstra...

Visual abstract of the study from Corina

We need a good biomarker for IgAN given the impoartance of immunosuppression (vs non-specific therapies: RASi, Flozins, ERA)

But the Gd-IgA doesn’t seem so impressive to me?

journals.lww.com/cjasn/pages/...

#NephSky @asnpublications.bsky.social #CJASN

VA by @corinateodosiu.bsky.social

New in the #CJASN series on Lifestyle Medicine and Kidney Health: how contemplative practices can reduce the clinical complications of stress, and help prevent the development, progression and complications of CKD and CKD risk factors. kidney.pub/CJASN0829

Sodium-Glucose Cotransporter-2 Inhibitor Therapy and... : Clinical Journal of the American Society of Nephrology study within the Veterans Health Administration included adults with an ADPKD diagnosis code who initiated SGLT2i between January 2017 and May 2023. Repeated measures models were used to evaluate eGFR...

Promising!

flozination in ADPKD (mostly older adults with DM or CVD) - presumably those with another valid indication - associated with slower GFR slope

journals.lww.com/cjasn/pages/... in @asnpublications.bsky.social #CJASN

With no obvious harm signal

Article in #CJASN "Lifestyle Medicine and Kidney Health" series discusses benefits of plant-based diet for patients with Chronic Kidney Disease (CKD).
bit.ly/CJASN0706
#ASNCJASN

Dr. Paul Palevsky shares his #CJASN perspective on the results of the Intravenous Amino Acid Therapy for Kidney Protection in Cardiac Surgery (PROTECTION) trial bit.ly/CJASN0678
#ASNCJASN

Glomerular Neovascularization
#DiabeticKidneyDisease #CaseReport

#SpatialTranscriptomics #Visium @10xGenomics

50-μm section multiplex IF

TEM▶️⏫Periglomerular Capillaries + de novo vascular anastomosis crossing Bowmen capsule

#KPMProject #CJASN 2024
journals.lww.com/cjasn/abstra...

Perspectives of Patients with #AKI

A systematic review in #CJASN identified 6 key themes in the experiences of 867 adults with AKI, including uncertainty, treatment burden, and life impairment. Authors call for education & comprehensive care.

Read more: https://journals.lww.com/cjasn/abstract/990…

An opposing view would be to throw caution to the wind and implement GDMT at a more accelerated rate similar to CHF

journals.lww.com/cjasn/fullte...

@asnkidney.bsky.social #CJASN
@brendonneuen.bsky.social

#NephJC

The Trojan Horse of Kidney Transplantation Returns: A... : Clinical Journal of the American Society of Nephrology ebate over payments to donors is discussed with particular emphasis on the national and international ramifications of such payments, the impact on normative “altruistic” donation, and the nature of t...

🆕 An interesting review on a call 📣 for financial neutrality for living kidney donation by G. Danovitch. A Trojan horse? 🐴
#cjasn

journals.lww.com/cjasn/abstra...

Setting Up Home Dialysis Programs: Now and in the Future - PubMed Home dialysis utilization has been growing in the United States over the past decade but still lags behind similar socioeconomic nations. More than half of dialysis facilities in the United States eit...

2. Home dialysis centers:
* US median is 1:14. Up to 1:25.
This is to accommodate for training patients alongside following up on established patients (clinics, complications, troubleshooting).

@grahamabra.bsky.social @ericweinhandl.bsky.social
#CJASN
pubmed.ncbi.nlm.nih.gov/37603364/

Nurses can provide more care than non-nurses, eg:

- Connecting/disconnecting the PD lines (separate discussion)

- Higher level observation of patient condition.

- other eg administer antibx.

Some rprts showed PD peritonitis even lower than self-care.

#CJASN
pubmed.ncbi.nlm.nih.gov/32188636/

#CJASN
🫘 Recurrence of FSGS post kidney transplant in one third of case
⬆️⬆️ Risk of graft loss by 5 fold
💯🌟Response to treatment is only seen in half of these patients.

#CJASN
🫘 Recurrence of FSGS post kidney transplant in one third of case
⬆️⬆️ Risk of graft loss by 5 fold
💯🌟Response to treatment is only seen in half of these patients.

Modified KDIGO algorithm for IgA nephropathy. Some open research questions #CJASN

Modified KDIGO algorithm for IgA nephropathy. Some open research questions #CJASN

Page not found – Precious Bodily Fluids

“@Nephro_Sparks: @kidney_boy is spot on with his assessment of the future of renal physiology kudos to #CJASN http://tinyurl.com/pkddwpa thanks