#CTSjournal authors Wenjie Wang and Da Xu discuss one of the pivotal findings of their recent study in the latest #TranslationalBytes post: bit.ly/4sSclqX

Learn more about first-in-class novel telomerase inhibitor, Imetelstat in this MOA mini review from #CTSjournal: bit.ly/4kzijtS

#CTSjournal Editor-in-Chief John Wagner gives a year end review for 2025 in the latest #TranslationalBytes: bit.ly/3OmO2SQ

Updated Deadline - March 15 is the last day to submit your research for publication in the upcoming Quantitative Medicine special collection from #CTSjournal: bit.ly/3Hwzq0g

Announcing the Biomedical Data Translator: Initial Public Release The growing availability of biomedical data offers vast potential to improve human health, but the complexity and lack of integration of these datasets often limit their utility. To address this, the...

Our recent #CTSjournal paper on the initial public release of the Biomedical Data Translator was selected as Paper of the Month by @ascptclinpharm.bsky.social
An open-source, knowledge graph–based reasoning system.
www.linkedin.com/feed/update/...
ascpt.onlinelibrary.wiley.com/doi/10.1111/...
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Check out student/trainee Maho Shibuya's research in #CTSjournal: bit.ly/48ldnnM

Learn more about the type 2 inflammatory disease treatment Dupilumab in this Mechanism of Action Mini Review from #CTSjournal: bit.ly/3X2Eqhc

Check out the November #CTSjournal Paper of the Month! bit.ly/3Lba2P7

The 2025 #CTSjournal award highlights the most outstanding CTS paper written by a student or trainee - learn more about this year's recipient in the latest #TranslationalBytes blog post: bit.ly/432VcAq

Are We Missing the Risk? Rethinking Restraint-Based Cardiovascular Monitoring in Nonclinical Toxicology Studies Identifying cardiovascular (CV) risks early in drug development is essential, especially for detecting arrhythmias and hemodynamic changes. Despite this, many nonclinical toxicology studies still rely

#CTSjournal authors Kim A. Henderson, Nicholas Ether, and Hugo M. Vargas discuss risks in nonclinical toxicology studies in the most recent #TranslationalBytes post: bit.ly/3IpbVXx

“Large” Time for a Primer: Larger Impacts with Large Language Models Large language models (LLMs), like ChatGPT, are no longer just tech-world curiosities; they’re increasingly making their way into drug discovery and clinical development. In this new Clinical and Tran

#CTSjournal author, James Lu discusses the role LLMs can have in the future of clinical pharmacology and translational science in the latest #TranslationalBytes: bit.ly/3IawfvA

This graphic previews the title of the "Translational Byes" post: "Enhancing Eligibility Assessment with Personal Health Records in a Fully Remote Trial" by Yoonjin Kim, MD The text is accompanied by a figure from the blog post ad the cover image of CTS

Check out the latest post from #TranslationalBytes! #CTSjournal author Yoonjin Kim discusses data integrity and personal health records in decentralized trials! bit.ly/4fFJHEa

Preview of a Mini-Review from CTS Graphic includes the journal cover, a figure from the mini-review, and the citation for the Mini-Review titled: "Model-Informed Paradigm in Drug Development - An End-to-End Case Study From Upadactinib Development"

In this mini-review from #CTSjournal, get a better understanding of MIDD by learning about the development of upadacitinib. bit.ly/3HbySwJ

A #CTSJournal Preview: PTPN2 and Leukopenia in Individuals With Normal TPMT and NUDT15 Metabolizer Status Taking Azathioprine Daniel, L.L., Nepal, P., Zanussi, J., Dickson, A.L., Straub, P., Miller-Fleming, T.W., Wei, W.-Q., Hung, A.M., Cox, N.J., Kawai, V.K., Mosley, J.D., Stein, C.M., Feng, Q., Liu, G., Tao, R. and Chung, C.P. (2025), PTPN2 and Leukopenia in Individuals With Normal TPMT and NUDT15 Metabolizer Status Taking Azathioprine. Clin Transl Sci, 18: e70220. https://doi.org/10.1111/cts.70220

Check out this brief report from #CTSjournal: bit.ly/43xd9rt

CTS Journal Preview Exploration of Using an Open-Source Large Language Model for Analyzing Trial Information: A Case Study of Clinical Trials With Decentralized Elements Includes a figure from the article.

📑 #CTSjournal RESEARCH SPOTLIGHT: "Exploration of Using an Open-Source Large Language Model for Analyzing Trial Information: A Case Study of Clinical Trials With Decentralized Elements", check the full research article referenced in the latest #TranslationalBytes.
bit.ly/4d83sCI

Experimental Insights and Recommendations for Successfully Performing Cerebral Microdialysis With Hydrophobic Drug Candidates Cerebral microdialysis in rodents represents a robust and versatile technique for quantifying the pharmacologically relevant unbound fraction of drugs in the brain. When this unbound fraction is simu...

Paper on the challenges of hydrophobic drugs in cerebral microdialysis accepted to #CTSJournal, #ASCPTJournalFamily Based on own data + intensive literature review, we developed a decision tree to guide future studies in testing unspecific binding prior to microdialysis: doi.org/10.1111/cts....

CTS Call for Papers: PhRMA Foundation Trainee Challenge Award The PhRMA Foundation and ASCPT’s journal Clinical and Translational Science (CTS) are partnering on a Challenge Award competition that will award trainees for outstanding papers addressing artificial

Just one more week to submit your AI/ML work for publication in the #CTSjournal special issue and for consideration for a @PhRMAFoundation Challenge Award! bit.ly/3YMSEDp

CTS Journal Preview: Check out this Article Rapid Identification and Phenotyping of Nonalcoholig Fatty Liver Disease Patients Using a Machine-Based Approach in Diverse Healthcare Systems (full citation follows)

Learn more about a rule-based algorithm providing an accurate, automated approach for rapidly identifying, stratifying, and sub-phenotyping NAFLD patients within a large EHR system in this article from #CTSjournal: bit.ly/42izurU

Attention Trainees! Submit your AI/machine learning paper to #CTSjournal for eligibility for a PhRMAFoundation challenge award! bit.ly/3YMSEDp

CTS Special Collection on Diversity, Equity, and Inclusion Editor-in-Chief John Wagner and Associate Editor Elvin Price stop by to discuss CTS‘s latest special collection on Diversity, Equity, and Inclusion. They share their thoughts on the importance of DEI in clinical pharmacology and translational science as well as trends found in the collection and where they see research headed in the future. They also discuss other opportunities to submit your research to CTS. Featuring: John Wagner and Elvin Price

In the latest from the #ASCPTPodcastChannel, #CTSjournal Editor-in-Chief John Wagner and Associate Editor Elvin Price stop by the podcast to discuss CTS‘s latest special collection on Diversity, Equity, and Inclusion! bit.ly/41ZzUTW

CTS Issue Preview February 2025: Volume 18, Issue 2 National Prescribing Practices for Pediatric Dystonia Among Providers in the United States Bridging Gaps in Oncology: Comparative Analysis of Development and Approval Pathways for Anticancer Drugs and Companion Diagnostic in the United States and Japan The Role and Challenges of Investigator-Initiated Trials in the Cell and Gene Therapy Products Boom in Mainland China Inhibition of Tacrolimus Metabolism by Cannabidiol and Its Metabolites In Vitro

Check out the latest issue of #CTSjournal - available online now: bit.ly/3XvWvEW

Translational Bytes Post Preview: What if you Could Experiment on Your Electronic Self by Iraj Hosseini, PhD

What is a digital twin? Learn more about this powerful concept for personalized medicine in the latest #TranslationalBytes post from #CTSjournal: bit.ly/41sYTz2

CTS Mini Review preview: "Imetelstat, a novel, first-in-class telomerase inhibitor: Mechanism of action, clinical, and translational science"

What is imetelstat? Find out in this #CTSjournal Mechanism of Action mini review: bit.ly/40EiOcr

CTS: Ringing in 2025, and Looking Back on a Strong 2024 -Translational Bytes Post

2024 was a great year fro #CTSjournal - read the year in review from Editor in Chief John Wagner in the latest #TranslationalBytes post. bit.ly/40rZzCR

Graphic explaining the aims of the CTS Call for Papers: Artificial Intelligence/Machine Learning The PhRMA Foundation and CTS are partnering on a Challenge Award competition that will award trainees for outstanding papers addressing artificial intelligence (AI) and machine learning (ML) in clinical and translational science. The PhRMA Foundation will provide the Challenge Award — a prize of $5,000 — to the first author of up to five winning papers, and CTS will publish these accepted manuscripts as part of a special collection. Submit manuscripts through CTS’s online submission system by March 15, 2025.

#CTSjournal and @PhRMAFoundation are partnering on a Challenge Award competition that will award trainees for outstanding papers addressing AI/ML in clinical and translational science: find out more about this exciting opportunity: bit.ly/3YMSEDp

CTS Call for Papers description image

AI and ML are at the forefront of a revolution in clinical and translational science - submit your AI/ML research for publication in this upcoming special collection for #CTSjournal: bit.ly/3YMSEDp

#CTSjournal author Pamela Davis discusses Electronic Health Record Big Data in the latest post from #TranslationalBytes: bit.ly/4a9MZg0

Author Ryo Nakamura provides more insight on his #CTSjournal study in the latest blog post from #TranslationalBytes: bit.ly/3VOjMB8