Secondary Necrosis Following Caspase‐Activation can Occur Independently of Gasdermin E Secondary necrosis follows apoptosis, but its mechanism is unclear. This study shows that although gasdermin E is cleaved during this process, it is not required for membrane rupture. Across multiple...

🧬 Just published in Advanced Science: New work from @linkermannlab.bsky.social showing that secondary necrosis can occur without Gasdermin E. A clear step forward in decoding regulated necrosis. #CellDeath #SecondaryNecrosis #GSDME #CaspaseInhibition #AdvancedScience #EditorPick shorturl.at/ITJe6