Differences Observed in Clinical Features of IgG4-ROD and Castleman Disease Both IgG4-ROD and Castleman disease may present as orbital masses or lacrimal gland enlargement, but they differ in imaging and histologic markers.

Chinese researchers have identified overlapping but distinct clinicopathologic features of immunoglobulin 4-related ophthalmic disease (#IgG4ROD), a form of IgG4-related disease (#IgG4RD), and #CastlemanDisease (CD). Report in the Indian Journal of Ophthalmology

Read more: https://bit.ly/48NGDDX

See what's to come in the next issue! Highlights of the November issue include a feature on medical #misinformation among patients, an in-depth look at #CastlemanDisease, the latest from ASH's Blood Journals' Portfolio, and more: https://ow.ly/wZLs50XiZLR
#HemeSky #MedSky

Screenshot of the paper title, "Spatial and single cell mapping of castleman disease reveals key stromal cell types and cytokine pathways" and authors. Link in second post.

Using lymph node resections from patients with #CastlemanDisease, researchers from @childrensphila.bsky.social applied #single-cell spatial proteomic and transcriptomic approaches to uncover key stromal–immune interactions that distinguish disease subtypes.

#omics 🧪

First in 45 Years: Scientists Discover New Subtype of Castleman Disease The discovery broadens the known spectrum of this rare disorder, emphasizing the critical role of collaboration with patient advocates. A newly discovered subtype of Castleman disease promises to improve...

First in 45 Years: Scientists Discover New Subtype of Castleman Disease #Science #HealthandMedicine #InfectiousDiseases #CastlemanDisease #MedicalResearch #HealthScience

AI Predicts Life-Saving Drug for Rare Disease, Patient Enters Remission Researchers used an AI-driven approach to identify adalimumab as a potential life-saving treatment for idiopathic multicentric Castleman’s disease (iMCD), successfully reversing a terminal case. The b...

AI Predicts Life-Saving Drug for Rare Disease, Patient Enters Remission 🔬💊🤖 www.azoai.com/news/2025020... #AI #DrugRepurposing #RareDisease #MedicalBreakthrough #MachineLearning #PrecisionMedicine #HealthcareInnovation #LifesavingTech #CastlemanDisease #Adalimumab