Rituximab An Effective Steroid-Sparing Strategy in IgG4-Related Disease Using real-world data, researchers assessed the glucocorticoid-sparing ability of rituximab in adult patients with IgG4-RD and found it was efficacious.

#Rituximab is an effective steroid-sparing strategy for patients with (#IgG4RD) that provides efficacy comparable to that with glucocorticoids even in those individuals with a more severe or relapsing course.

Read here: https://bit.ly/4sXz1Gt

#RareDisease #MedSky

What happens when we recognize IgG4‑RD early?

Less organ involvement.

Awareness leads to answers.

Early diagnosis changes outcomes.

Find trusted resources and education at zurl.co/K8uwZ

#IgG4RD #RareDiseaseAwareness #EarlyDiagnosis #PatientEducation

4/4 is IgG4-RD Awareness Day. The image promotes an interview with Donna Shipp about their IgG4-RD patient journey. Includes "Rare Care" podcast graphics and the text, "Listen Now.

📆 4/4 is #IgG4RD Awareness Day

Today we recognize all those affected and share Donna Shipp’s story on the Rare Care podcast. A former nurse, she was misdiagnosed with cancer for 6 months before receiving the correct diagnosis.

🎧 Listen: https://bit.ly/4c9t963

#RareDisease #RareCare #MedSky

Join us in celebrating IgG4-RD Awareness Day today! IgG4‑Related Disease is rare, complex, and often misunderstood. 💜

AiArthritis has created dedicated tools and resources at: zurl.co/ErwcJ

#IgG4RD #IgG4RDAwarenessDay #RareDiseaseAwareness #ChronicIllness #HealthEducation

Today is IgG4-Related Disease (IgG4-RD) Awareness Day, and we are shining a massive spotlight on 2026 Infusion Access Foundation Champion, Mahsa Pazokifard!

🔗 Learn more about Mahsa’s mission: zurl.co/U0il3

#IgG4RD #IgG4RDAwareness #IAFChampions

Turning Up the Volume on IgG4-RD Awareness and Diagnosis For a disease as rare and complex as IgG4-RD, raising awareness and addressing critical gaps in care requires more than individual efforts—it demands collaboration.

For nearly a year, Andy and his wife Kat searched for answers on his journey to an eventual IgG4-related disease (IgG4-RD) diagnosis.

Learn more about Andy and Kat’s journey: zurl.co/yHUo8

#IgG4RD #RareDisease

IgG4 Surge Trend Can Predict IgG4-RD Relapse An increase in IgG4 levels over time, rather than a single-timepoint IgG4 measurement, can predict relapse in IgG4-RD, according to recent research.

An increase in #IgG4 levels over time, rather than a single-timepoint IgG4 measurement, can predict relapse in immunoglobulin G4-related disease (IgG4-RD) and guide early treatment intensification.

Read more: https://bit.ly/3Pye8Dj

#RareDisease #IgG4RD #MedSky

Medication Combination Effective for IgG4-RD With Coronary Involvement IgG4-RD with vascular involvement is not uncommon and can lead to serious complications such as ischemic heart disease or aneurysm rupture.

The combination of glucocorticoids with steroid-sparing immunosuppressants is effective in the management of immunoglobulin G4-related disease (#IgG4RD) associated with coronary involvement. Study in @journalofcmr.bsky.social @scmrorg.bsky.social

Read here: https://bit.ly/45lwTPe

Ultrasonography Useful in Diagnosing, Tracking Progression of IgG4-RKD Recent research showed that combinations of ultrasonographic features were useful to identify and track patients with IgG4-RD-related kidney disease.

#Ultrasonography features in immunoglobulin G4-related disease (#IgG4RD)-associated #KidneyDisease (IgG4-RKD) show characteristic findings that correlate with serological disease and the extent of kidney dysfunction. Study in Frontiers in Medicine

Read more: https://bit.ly/3Z0Oqsg

Case Report: IgG4-Related Colitis Managed With Steroids and Rituximab A 34-year-old male patient with IgG4-related colitis was successfully managed with steroids and rituximab, without the need for colectomy.

A patient with #Colitis associated with immunoglobulin G4-related disease (#IgG4RD) was successfully managed with #Steroids and #Rituximab. Case report in @annalsofim.bsky.social Clinical Cases

Read more: https://bit.ly/3Kpw4hd

#RareDisease #MedTwitter #InternalMedicine

Presidential Medal Follows Lifetime of Work in Rheumatology's Complex Diseases The American College of Rheumatology awarded its 2025 Presidential Gold Medal to Dr. Eric Matteson for his achievements and service.

The American College of Rheumatology awarded its 2025 Presidential Gold Medal to Dr. Eric Matteson for his achievements and service, working with challenging #AutoimmuneDiseases, from #ANCA-associated vasculitis and #Scleroderma to #PolyarteritisNodosa and #IgG4RD

Read here: https://bit.ly/3KVgf1O

Case Report: Concurrent SAPHO Syndrome and IgG4-RD A middle-aged female patient was concurrently diagnosed with SAPHO syndrome and IgG4-RD and successfully treated with upadacitinib and prednisone.

A female patient in her 40s was diagnosed with coexisting synovitis, acne, pustulosis, hyperostosis, and osteitis (#SAPHO) syndrome and immunoglobulin G4-related disease (#IgG4RD). Case report published in Clinical & Translational Immunology.

Read here: https://bit.ly/4pUB6RX

#RareDisease #MedSky

Differences Observed in Clinical Features of IgG4-ROD and Castleman Disease Both IgG4-ROD and Castleman disease may present as orbital masses or lacrimal gland enlargement, but they differ in imaging and histologic markers.

Chinese researchers have identified overlapping but distinct clinicopathologic features of immunoglobulin 4-related ophthalmic disease (#IgG4ROD), a form of IgG4-related disease (#IgG4RD), and #CastlemanDisease (CD). Report in the Indian Journal of Ophthalmology

Read more: https://bit.ly/48NGDDX

ML Model Differentiates Between IgG4-Related Sialadenitis, Primary Sjögren's Syndrome Researchers developed a machine learning model to help differentiate between IgG4-related sialadenitis and primary Sjögren's syndrome.

Researchers developed a #MachineLearning model that can be used to differentiate between immunoglobulin G4-related disease (#IgG4RD) associated with #Sialadenitis and primary Sjögren’s syndrome (#pSS). Study in International Dental Journal.

Read more: https://bit.ly/3XTW4UI

#RareDisease #MedSky

Distinct Allergen-Specific IgE, IgG4 Signatures Define Organ Involvement in IgG4-RD New research showed that IgG4-RD features distinct allergen-specific IgE and IgG4 signatures, with some environmental antigens tied to organ involvement.

Immunoglobulin G4-related disease (#IgG4RD) is associated with distinct allergen-specific IgE and IgG4 signatures, with certain environmental antigens linked to organ-specific involvement. Study in @allergy-eaaci.bsky.social

Read here: https://bit.ly/43SpXbH

#RareDisease #MedSky

Mahsa Pazokifard shares her powerful story of spending years searching for answers before finally being diagnosed with IgG4-Related Disease — and how self-advocacy became her lifeline.
Listen to the full episode: ghlf.org/the-health-a...
#RareDisease #IgG4RD #PatientAdvocacy

Peripheral T Lymphocyte Activation State May Predict Abatacept Response in IgG4-RD New research showed that patients with rare variants affecting the CTLA-4 pathway were more likely to respond to abatacept than those without the variants.

Investigators have found that baseline T-cell activation patterns may predict which patients with immunoglobulin G4-related disease (#IgG4RD) are more likely to respond to #Abatacept, according to a letter to the editor in the European Journal of Internal Medicine.

Read more: https://bit.ly/3Me1kzY

IgG4-RD Gastrointestinal Manifestations Have Diverse Pathological, Endoscopic Features Twenty-four cases of IgG4-GID were identified; of these, 20 cases included IgG4-RD manifestations in organs other than those in the gastrointestinal system.

Gastrointestinal manifestations of immunoglobulin G4-related disease (#IgG4RD) have diverse pathological and endoscopic features, according to a study published in the Journal of Gastroenterology.

Learn more: https://bit.ly/48df2M0

#RareDisease #Gastroenterology #ImmunoglobulinG4RelatedDisease

graphic is human organs

Stay current in clinical practice. This #CME activity helps you review key aspects of IgG4-related disease, from diagnosis to treatment.

Earn credit while testing your expertise.

Begin here ▶️ ms.spr.ly/63320smZfe

#IgG4RD

#ACR25: Katharine Provencher, director of advocacy for the IgG4ward, which represents people like her husband, Andy, who has #IgG4RD. Provencher spoke Oct. 26 at the 2025 ACR Convergence

Image & quote taken by Senior Correspondent Larry Luxner

#RareDisease #RheumSky #MedSky

#ACR25: Alireza Meysami, MD, a rheumatologist and expert in IgG4-RD, speaking Oct. 26 at the 2025 ACR Convergence in Chicago.

Image and quote taken by Senior Correspondent, Larry Luxner

#RareDisease #Rheumatology #RheumSky #IgG4RD #MedSky

Rare Diseases Weekly News – August 21st 2025 🧬 This Week in Rare Diseases: FDA Approvals, Global Partnerships, Breakthrough Therapies, and More This week’s Rare Diseases roundup brings […] The post Rare Diseases Weekly News – August 21st 2025 appeared first on LucidQuest Ventures.

FYI: LucidQuest Views >>> Rare Diseases Weekly News – August 21st 2025 #News #rarediseases #IgG4RD #OCD #GPP Comment below!

Rare Diseases Weekly News – August 21st 2025 🧬 This Week in Rare Diseases: FDA Approvals, Global Partnerships, Breakthrough Therapies, and More This week’s Rare Diseases roundup brings […] The post Rare Diseases Weekly News – August 21st 2025 appeared first on LucidQuest Ventures.

ICYMI: LucidQuest Views >>> Rare Diseases Weekly News – August 21st 2025 #News #rarediseases #IgG4RD #OCD #GPP Comment below!

Rare Diseases Weekly News – August 21st 2025 🧬 This Week in Rare Diseases: FDA Approvals, Global Partnerships, Breakthrough Therapies, and More This week’s Rare Diseases roundup brings […] The post Rare Diseases Weekly News – August 21st 2025 appeared first on LucidQuest Ventures.

LucidQuest Views >>> Rare Diseases Weekly News – August 21st 2025 #News #rarediseases #IgG4RD #OCD #GPP Comment below!

Thanks to IgG4ward!’s dedication, Sam is now featured in their newsletter, website, and community gatherings, providing practical support at your fingertips. Learn more about this great partnership: steroidsandme.com/article/sam-...

#Partners #PatientAdvocacy #PatientSupport #IgG4RD

💡Rare Disease Spotlight: IgG4-RD

Learn more about this rare disease with our latest article checkrare.com/newly-approv...

#CheckRare #RareDisease #IgG4RD #RareAutoimmune #RareSkin

🆕 Exciting time to dive into this, especially with the FDA’s recent approval of the first and only treatment, Inebilizumab😀❣️

#IgG4RD #Rheumsky

Finally also showing the results from the #MITIGATE study in #IgG4RD #igg4ward
#inebilizumab being approved by @fda.gov now for #IgG4RD !

Today is IgG4-Related Disease Awareness Day 🧬
This rare autoimmune condition can affect multiple organs & is often misdiagnosed as IBS, cancer, pancreatitis & more.
Diagnosis is often delayed. Awareness can change that. 💙
#IgG4RD #RareDisease #CreakyJoints #GHLF

First FDA-Approved IgG4-RD Treatment A humanized monoclonal antibody that targets CD19+ B cells becomes the first and only FDA-approved treatment for immunoglobulin G4–related disease, reducing flare risk and glucocorticoid use in clinic...

The FDA has approved inebilizumab as the first treatment for IgG4-RD, showing an 87% reduction in flare risk. Learn more about its impact on patient care and the latest clinical data. #IgG4RD #FDAApproval