I am very happy that we again managed to invite two world-leading scientists as keynotes for the 6th Virtual @chembiotalks.bsky.social.

We are working on an exciting additional program. Stay tuned!

Mailing list: fd24.formdesk.com/universiteit...

#ChemSky #ChemBio #ChemBioTalks

We are excited that the 5th Virtual #ChemBioTalks attracted 450 participants from 50 different countries world-wide. Thank you all for making this such an engaging event!

If you want to suggest speakers and keynotes for 2026, please do so by October 31st at ChemBioTalks@gmail.com

#ChemBio #ChemSky

We had amazing 5th Virtual #ChemBioTalks. Thank you to all the speakers and organizers for making this possible!

Already mark your calendars for the 6th edition on September 29th, 2026. You are invited to suggest speakers via ChemBioTalks@gmail.com.

#ChemBio #ChemSky #DrugDiscovery

PROTAC targeted protein degraders: the past is prologue - Nature Reviews Drug Discovery Targeted protein degradation with proteolysis-targeting chimeras (PROTACs) has the potential to tackle disease-causing proteins that have historically been highly challenging to target with conventional small molecules. This article summarizes the first two decades of PROTAC discovery and discusses key areas for the future of this therapeutic modality, including establishing the target classes for which it is most suitable and extending its application beyond oncology.

Inspiring talk by @craigmcrews.bsky.social at the 5th Virtual #ChemBioTalks. He talked about the power of inducing protein-protein interactions for #DrugDiscovery and the paradigm-shift from occupancy-driven to event-driven pharmacology that this enables. www.nature.com/articles/s41...

Inspiring keynote lecture by @craigmcrews.bsky.social at the 5th Virtual #ChemBioTalks. He reported on his group's pioneering work on proximity-inducing molecules for applications in #DrugDiscovery.
www.nature.com/articles/s41...
#ChemSky #ChemBio

Very interesting talk by Jenn Prescher at the 5th Virtual #ChemBioTalks. She talked about the tools that her group is developing to track RNA using (multiplexed) bioluminescence. www.nature.com/articles/s41...

We had a great Flash Talk session at the 5th Virtual #ChemBioTalks. We heard about #metabolomics to understand bone repair (Jingzhi Fan), fluorogenic triazinium probes (Veronika Šlachtová) and masked acylation reagents for #ChemBio (@shubha-pani.bsky.social).

The 5th Virtual #ChemBioTalks continue with an insightful talk by @kellychibale.bsky.social. He talked about his group's research into new treatments for #malaria. Great insights into the repurposing of anti #cancer #kinase inhibitors to treat P. falciparum. onlinelibrary.wiley.com/doi/10.1002/...

Insightful talk by @cathleenzeymer.bsky.social at the 5th Virtual #ChemBioTalks. She talked about the design and evolution of artificial #enzymes for photocatalysis. Interesting insights into both repurposing of existing enzymes and de novo design. onlinelibrary.wiley.com/doi/abs/10.1...

Exciting talk by Christian Dallago (@machine.learning.bio) at the 5th Virtual #ChemBioTalks. He talked about the development of #MachineLearning tools to better understand biological systems. Great insights how #BigData from sequencing can be used to predict function. www.cell.com/trends/bioch...

We continue the 5th Virtual #ChemBioTalks with an exciting talk by Chengqi Yi, who talked about targeting and manipulating mutated #RNA to treat human diseases. Interesting insights into site-specific RNA modification. www.nature.com/articles/s41...
#ChemBio #ChemSky #DrugDiscovery

Single-cell multi-omics in the medicinal plant Catharanthus roseus - Nature Chemical Biology The medicinal plant Catharanthus roseus is a source of leading anticancer drugs. The monoterpene indole alkaloid (MIA) biosynthetic pathway in C. roseus has now been analyzed using a complementary, multi-omics, single-cell approach. This identified clusters of genes involved in MIA biosynthesis and cell-type-specific partitioning in the MIA biosynthetic pathway.

Great talk by @oconnorlab.bsky.social at the 5th Virtual @chembiotalks.bsky.social #ChemBioTalks.
She talked about the amazing diversity of natural products that plants make and the application of single-cell #multiomics technologies to deceipher their biosynthesis. www.nature.com/articles/s41...

The Virtual #ChemBioTalks get under way with our first keynote lecture by Sarah O'Connor (@oconnorlab.bsky.social), who gave exciting insights into, how plants can make diverse #NaturalProducts. onlinelibrary.wiley.com/doi/full/10....
#ChemBio #ChemSky

We get under way with the 5th Virtual #ChemBioTalks. We look forward to a great day of diverse topics in #ChemBio science.

If you attend and want to share your thoughts, make sure to link @chembiotalks.bsky.social and #ChemBioTalks.

We are getting ready for the 5th Virtual #ChemBioTalks. Very excited for a full day of exciting #ChemBio science.

If you experience any issues, please reach out at ChemBioTalks@gmail.com

Last chance to register for free for the 5th Virtual #ChemBioTalks tomorrow!

Great lineup of talks including keynotes Sarah O'Connor (@oconnorlab.bsky.social) and @craigmcrews.bsky.social and three Flash Talks by the winners of our abstract challenge

web.cvent.com/event/60e9f3...
#ChemBio #ChemSky

Excited to hear about the amazing research from the @chembiobryan.bsky.social group on taming acyl chlorides for #ChemBio applications from the first author of the @natchem.nature.com paper, @shubha-pani.bsky.social.

Register for free for the 5th Virtual #ChemBioTalks to join: cvent.me/G1geWW

The third and final Flash Talk of the 5th Virtual #ChemBioTalks will be given by Shubhashree Pani (@shubha-pani.bsky.social) from the group of @chembiobryan.bsky.social: "Masked acylating agents for proximity labeling of biomolecules" www.nature.com/articles/s41...
#ChemBio #ChemSky #DrugDiscovery

5th Virtual ChemBioTalks are happening Sept 30, 2025 — an afternoon of inspiring Chemical Biology talks from leading scientists worldwide 🌍🧪
🎤 Keynotes: Sarah O’Connor & Craig Crews
🆓 Free registration: buff.ly/5UR13PW

Come for the science, stay for the global connections 💡
#ChemBioTalks #ChemBio