#NeovascularAgerelatedMacularDegeneration #nAMD

APEX1 redox-specific inhibitor APX2009 (intravitreal) ⏬🐭👁️pathological #Angiogenesis

Laser-induced #ChoroidNeoVascularization
Vldlr-/- mouse subretinal neovascularization

Timothy Corson lab #Angiogenesis 2025
link.springer.com/article/10.1...

#Tubulin #Angiogenesis

TUBB6 (β6V tubulin)
enriched in retinal #EndothelialCell #Pericyte
⏫in👤#AMD &🐭 #ChoroidNeoVascularization

Intravitreal siRNA Tubb6 ⏬ pathological angiogenesis in🐭 #OIR & 🐭laser CNV

YBX1 stabilizes TUBB6 ➡️
⏫Wnt3a/FZD8-Angiogenesis

#THNO 2025
www.thno.org/v15p2680.htm