#ClinSci journal ‘Evaluating skeletal muscle wasting and weakness in models of critical illness’ #ReviewArticle #OpenAccess doi.org/10.1042/CS20...

#ResearchArticle from #ClinSci journal ‘Impact of the natural female reproductive aging on the rat serum lipidome’ #OpenAccess doi.org/10.1042/CS20...

Characterization of cardiac phenotype in WT/Foz mice after 24 weeks feeding period

Bott et al. investigate the mechanisms linking heart and liver diseases in this #OA #ClinSci research article, uncovering that MASH may actively contribute to development of pathological structural changes in the heart 🧪 doi.org/10.1042/CS20...

Impact of the natural female reproductive aging on the rat Serum lipidome Perimenopause is a transitional phase leading to female reproductive senescence, which can cause vasomotor symptoms and increase the risk of osteoporosis, obesity, and metabolic-related disturbances i...

Impact of the natural female reproductive aging on the rat Serum lipidome #ClinSci #MassSpec portlandpress.com/clinsci/arti...

Cartoon to illustrate the differential roles of PDCD10 in modulating TGF-β signalling in pancreatic carcinoma cells.

Is PDCD10/CCM3 a potential target for pancreatic ductal adenocarcinoma? This commentary from Hendrik Ungefroren dissects the recently published #ClinSci paper: PDCD10 promotes the tumor-supporting functions of TGF-β in pancreatic cancer. 🧪 doi.org/10.1042/CS20...

Factors contributing to sex differences in salt sensitivity of blood pressure

Explore the current understanding of aging and sex differences in salt sensitivity of blood pressure in this #ClinSci review by @annetkiraboc1.bsky.social, Mert Demirci and Jeremiah M. Afolabi 🧪 doi.org/10.1042/CS20...

#Colchicine stabilizes #SmoothMuscleCell contractile phenotype & alleviates🐭#AbdominalAorticAneurysm (local elastase + BAPN in water)
ep.1

⏬collagen
↔️elastin
⏬#VascularInflammation
⏬immune cell infiltr
⏬vascular wall #Pyroptosis SMC or immune cells?🤔

#ClinSci 2023
portlandpress.com/clinsci/arti...

Factors contributing to sex differences in salt sensitivity of blood pressure This figure highlights the potential mechanisms by which sex hormones modulate salt sensitivity of blood pressure. ENaC, epithelial sodium channel; MR, mineralocorticoid receptor; Na/H, sodium-hydrogen; PR, progesterone receptor; SNS, sympathetic nervous system.

Explore the current understanding of aging and sex differences in salt sensitivity of blood pressure in this #ClinSci review by Annet Kirabo et al. 🧪
doi.org/10.1042/CS20...