Coccidioidomycosis: The brief life and enduring impact of Alejandro Posadas

📣 Alejandro Posadas, the Argentine behind #Coccidioides posadasii, was the son of Spanish emigrants. He identified C. posadasii in the wounds of a cavalry soldier, and died of #tuberculosis at 32.

#IDSky #clinmicro #mycology #coccidioidomycosis

https://ow.ly/jkTx50Yp5Ri

Outdoor workers need more protections from Valley fever Valley fever is recognized as a work-related disease in California, but not in Arizona or other states where it is also now widespread.

In a new study, researchers from #UCBerkeley #PublicHealth and U. of Michigan found that outdoor workers face high risks from #ValleyFever— and need stronger protections on the job. bit.ly/4gAh5wk
#Coccidioides #Fungus #OutdoorWorkers #WildlandFirefighters #Epidemiology #BerkeleyPublicHealth

33356 - NeXGen Fungal / AFB Next Generation Sequencing (NGS) NeXGen Hybrid-Capture NGS offers comprehensive pathogen detection, increased sensitivity & specificity, & simultaneous detection of multiple pathogens.

These risks highlight why fungal diseases are a #OneHealth concern, affecting people, animals, and the environment.

🧬 NeXGen Fungal / AFB NGS Testing: www.eurofins-viracor.com/our-testing/...

#Coccidioides #Aspergillus #Candida

🧵 2/3

I'm thrilled to join the #OHSU ID faculty in early 2026, where I will continue my work to find a cure for the fungus #Coccidioides, which causes Valley Fever. Thanks to #UCSF for a wonderful 15 years of medicine & science. Excited for this new chapter ahead! Recruiting for the Homer Lab soon!

New rapid test could revolutionize valley fever diagnosis in Arizona A new 10-minute test for valley fever could help patients get faster, more accurate treatment.

Rapid test could revolutionize valley #fever #diagnosis in #Arizona ...

| #coccidioidomycosis | #fungi | #infection | #diagnostics | #pathogen | #Coccidioides | Via @azfamily.com‬

From farm to field: testing different biocrust cultivation approaches and application techniques in the Sonoran Desert Drylands are among the most degraded ecosystems globally and are difficult to restore due to limited water availability. Biocrusts are a key component of maintaining soil stability and function in th...

🌵In this study, we evaluated how different methods affect the success of biocrust restoration in arid environments, and potential of cultivated biocrusts as a sustainable tool for restoring degraded drylands—especially in the face of climate change and increasing #Coccidioides #valleyfever.

Testing for Rapid and Accurate Detection of Life-Threatening Dimorphic Fungi | Eurofins Viracor Eurofins Viracor launches rapid qPCR assays for dimorphic fungi, enabling faster, accurate diagnosis and targeted antifungal treatment.

📰 PRESS RELEASE ALERT! 🧪 New quantitative real-time PCR assays for dimorphic fungi, now available. 👇READ NOW 🔎 PRESS RELEASE:
www.eurofins-viracor.com/news-and-eve...

#Blastomyces #Histoplasma #Coccidioides #Cryptococcus #DimorphicFungi #dimorphicfungi

Valley Fever: Danger Lurking in a Dust Cloud.

Review article about the dust-borne pathogen #Coccidioides

knowthecause.com/wp-content/u... #MicroSky #IDSky

Looking forward to this week's MMI Thursday Seminar featuring Bridget Barker

THURSDAY, MAY 1
12:00Noon
@johnshopkinssph.bsky.social
Becton Dickinson Hall
W1020

All members of @jhu.edu community are welcome!

#coccidioides #fuungalpathogens

Top: Micrographs of fixed samples from each flask at the time of RNA harvest. Endospore release was first observed on day 3. Bottom: Schematic of Regulation of gene expression in Coccidioides development. The data uncover regulatory modules in Coccidioides development. The majority of Coccidioides transcription factors (TFs), depicted as triangles in the figure, show enhanced expression in spherules compared to hyphae. These TFs, along with RYP1 (green hexagon) and a second regulator whose motif is reported here, guide the expression of endospore-associated transcripts and secreted effectors, including proteases. RYP1 also controls a core regulon, that is, expressed in both spherules and hyphae via a canonical RYP1 motif. Finally, in arthroconidia, RYP1 impacts the transcriptome, but likely through indirect regulation of one or more additional key regulators.

Coccidioides is a fungal #pathogen that forms a unique structure, the spherule. This transcriptomic study of #Coccidioides development reveals spherule-specific gene regulation, Ryp1-dependent virulence factors, and potential #antifungal therapeutic targets @plosbiology.org 🧪 plos.io/4cINMpl

Top: Micrographs of fixed samples from each flask at the time of RNA harvest. Endospore release was first observed on day 3. Bottom: Schematic of Regulation of gene expression in Coccidioides development. The data uncover regulatory modules in Coccidioides development. The majority of Coccidioides transcription factors (TFs), depicted as triangles in the figure, show enhanced expression in spherules compared to hyphae. These TFs, along with RYP1 (green hexagon) and a second regulator whose motif is reported here, guide the expression of endospore-associated transcripts and secreted effectors, including proteases. RYP1 also controls a core regulon, that is, expressed in both spherules and hyphae via a canonical RYP1 motif. Finally, in arthroconidia, RYP1 impacts the transcriptome, but likely through indirect regulation of one or more additional key regulators.

Coccidioides is a fungal #pathogen that forms a unique structure, the spherule. This transcriptomic study of #Coccidioides development reveals spherule-specific gene regulation, Ryp1-dependent virulence factors, and potential #antifungal therapeutic targets @plosbiology.org 🧪 plos.io/4cINMpl

Top: Micrographs of fixed samples from each flask at the time of RNA harvest. Endospore release was first observed on day 3. Bottom: Schematic of Regulation of gene expression in Coccidioides development. The data uncover regulatory modules in Coccidioides development. The majority of Coccidioides transcription factors (TFs), depicted as triangles in the figure, show enhanced expression in spherules compared to hyphae. These TFs, along with RYP1 (green hexagon) and a second regulator whose motif is reported here, guide the expression of endospore-associated transcripts and secreted effectors, including proteases. RYP1 also controls a core regulon, that is, expressed in both spherules and hyphae via a canonical RYP1 motif. Finally, in arthroconidia, RYP1 impacts the transcriptome, but likely through indirect regulation of one or more additional key regulators.

Coccidioides is a fungal #pathogen that forms a unique structure, the spherule. This transcriptomic study of #Coccidioides development reveals spherule-specific gene regulation, Ryp1-dependent virulence factors, and potential #antifungal therapeutic targets @plosbiology.org 🧪 plos.io/4cINMpl

Valley fever cases surge in California, already way up from recent years Valley fever is caused by inhaling spores of coccidioides, a fungal pathogen that thrives in the drier and dustier regions of the state.

Cases of soil-borne #coccidioides infections (Valley Fever) are surging in California.

As of the end of November, 11,076 cases had been confirmed statewide, a 20% increase compared to last year’s total & a ~47% jump from 2022.

www.latimes.com/environment/...

Valley fever cases surge in California, already way up from recent years Valley fever is caused by inhaling spores of coccidioides, a fungal pathogen that thrives in the drier and dustier regions of the state.

Cases of soil-borne #coccidioides infections (Valley Fever) are surging in California.

As of the end of November, 11,076 cases had been confirmed statewide, a 20% increase compared to last year’s total & a ~47% jump from 2022.

www.latimes.com/environment/... #MicroSky