#SingleCellTranscriptomics of #bonemarrow in #Type2Diabetes reveals impaired #cytokinesignaling, reduced #osteoclast activity, and diminished Cd36+ precursor differentiation, driven by dysregulated AP-1 transcription factor activity.
#OpenAccess: doi.org/10.1016/j.ge...
Hashtag
#CytokineSignaling
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DNA Damage-driven Inflammatory Cytokines: Reprogramming of Tumor Immune Microenvironment and Application of Oncotherapy
This comprehensive review explores the interplay between the #DNADamage response and #CytokineSignaling in #Tumors, highlighting their dual #Immunoregulatory roles and therapeutic implications. #medsky
Read more: link.springer.com/article/10.1...
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🔬 How do β-cells respond to IFN-α? 🔬
Join TSS as we explore β-cell heterogeneity in the acute IFN-α response & its role in T1D pathogenesis.
📖 Register now: us02web.zoom.us/meeting/regi...
#DiabetesResearch #T1D #BetaCells #CytokineSignaling #IsletBiology #Autoimmunity #Microscopy
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