Does combining IV #dexamethasone + #dexmedetomidine improve analgesia duration after #supraclavicular block?

Watch this new video abstract where Professor Albrecht takes us through this triple-blind RCT.

Read the article here: www.bjanaesthesia.org/article/S0007-0912(25)00...

Check out the February issue of the BJA #miniflipbook, which showcases all of our #FREE articles on topics including: #stellateganglionblock #bonferroni #statistics #fluidbalance #dexmedetomidine #fentanyl #prostaglandins #regionalanaesthesia #PPCs

https://bja136-2.elsevierdigitaledition.com/

New #RCT showing no #significantdifference in analgesia with the addition of #dexmedetomidine to #dexamethasone with a #supraclavicularbrachialplexus block

www.bjanaesthesia.org/article/S0007-0912(25)00...

Check out the February issue of the BJA #miniflipbook, which showcases all of our #FREE articles on topics including: #stellateganglionblock #bonferroni #statistics #fluidbalance #dexmedetomidine #fentanyl #prostaglandins #regionalanaesthesia #PPCs

https://bja136-2.elsevierdigitaledition.com/

Check out the February issue of the BJA #miniflipbook, which showcases all of our #FREE articles on topics including: #stellateganglionblock #bonferroni #statistics #fluidbalance #dexmedetomidine #fentanyl #prostaglandins #regionalanaesthesia #PPCs

https://bja136-2.elsevierdigitaledition.com/

Check out the February issue of the BJA #miniflipbook, which showcases all of our #FREE articles on topics including: #stellateganglionblock #bonferroni #statistics #fluidbalance #dexmedetomidine #fentanyl #prostaglandins #regionalanaesthesia #PPCs

https://bja136-2.elsevierdigitaledition.com/

Check out the February issue of the BJA #miniflipbook, which showcases all of our #FREE articles on topics including: #stellateganglionblock #bonferroni #statistics #fluidbalance #dexmedetomidine #fentanyl #prostaglandins #regionalanaesthesia #PPCs

https://bja136-2.elsevierdigitaledition.com/

Unresponsiveness under #dexmedetomidine was distinct from unresponsiveness under #propofol, and more similar to N2 sleep

www.bjanaesthesia.org/article/S0007-0912(25)00...

Perioperative #dexmedetomidine did not reduce death or complications in adults undergoing #CPB assisted #cardiacsurgery

www.bjanaesthesia.org/article/S0007-0912(25)00...

Perioperative #dexmedetomidine does not reduce postoperative incidence of #AKI after #partialnephrectomy

www.bjanaesthesia.org.uk/article/S0007-0912(25)00...

In this new commentary, Tian et al. remind us that language bias, limited data, and suboptimal meta-analytic methods may overstate the benefit of intraoperative #dexmedetomidine on #cancer prognosis in a recent meta-analysis

bjanaesthesia.org/article/S000...

The role of intraoperative #dexmedetomidine in cancer prognosis remains unclear. Variable dosing, confounding anaesthetic medications, and lack of tumour-specific analyses limit conclusions.

www.bjanaesthesia.org/article/S000...

Does intraoperative #dexmedetomidine improve #cancer outcomes? Heterogeneity, inconsistent dosing, and conflicting survival data raise doubts. Tumour-specific RCTs are needed for clarification

www.bjanaesthesia.org/article/S000...

Dexmedetomidine relieves LPS-induced acute lung injury by boosting HIF-1a/ACOD1 driven anti-inflammatory macrophage polarization - Genes & Immunity Genes & Immunity - Dexmedetomidine relieves LPS-induced acute lung injury by boosting HIF-1a/ACOD1 driven anti-inflammatory macrophage polarization

#Dexmedetomidine relieves #LPS-induced #acute #lung #injury by boosting HIF-1a/ACOD1 driven anti-#inflammatory #macrophage #polarization

#Genes & #Immunity @springernature.com
www.nature.com/articles/s41...

#Dexmedetomidine may reduce postoperative #AKI risk in children, but more studies needed to confirm optimal dosing and timing with efforts to exclude potential biases and confounding

www.bjanaesthesia.org.uk/article/S000...

Does intraoperative #dexmedetomidine use have an impact on #cancer
outcomes? The answer still seems to be uncertain. #BJA #survival #recurrence

www.bjanaesthesia.org/article/S000...

Alpha-2 agonists can modulate gene expression in renal cell carcinoma. Despite this, Wong et al. provide reassuring evidence that intraoperative #dexmedetomidine use was not associated with #RCC progression or survival.

#nephrectomy #survival

www.bjanaesthesia.org/article/S000...

Different anesthetics, same result: unconsciousness by shifting brainwave phase By demonstrating how two distinct anesthetic drugs achieve the same result — unconsciousness — a new study by neuroscientists at MIT's Picower Institute identifies a potential signature of uncons...

#MIT discovered a universal #brain-wave signature that marks unconsciousness—across #anesthetics like #ketamine and #dexmedetomidine.
Out-of-phase waves within hemispheres + in-sync waves across hemispheres = you’re out.
#neuroscience #neuroskyence #medsky #neuro #advancements

BJA Vol. 134 No. 6

Check out the new #miniflippbook version of the BJA, with #FREE articles on: #lidocaine # diuretics #palliativecare #dexmedetomidine #multimorbidity # postsurgicalpain #fibromyalgia #opioids

By leveraging advances in #Bayesian statistical methods, this meta-analysis quantifies the role of publication bias in the field of #dexmedetomidine for #delirium prevention in #cardiac surgery patients

Brain Wave Phase Locking May Be Key to Unconsciousness - Neuroscience News Despite acting through different molecular mechanisms, ketamine and dexmedetomidine both disrupt brain wave phase alignment in ways that reliably induce unconsciousness.

🧠 #Brain Wave Phase Locking May Be Key to #Unconsciousness

@neurosciencenews.bsky.social
@mitpress.bsky.social

#Neuroscience #ketamine #dexmedetomidine
@chrisggarrod.bsky.social @fabrizio78.bsky.social @chidambara09.bsky.social @andrewincontact.bsky.social
neurosciencenews.com/brain-wave-c...

BJA Vol. 134 No. 5

Check out the new mini-flip book version of the BJA.

FREE articles on: #ARBs #careplans #AI #sevoflurane #dexmedetomidine #polio #clotting #epidural #DPE #moprphine #fluids #ultrasound

bja134-5.elsevierdigitaledition.com

IGALMI Sees Remarkable Growth in Market Accessibility for Mental Health Treatments The IGALMI market is expanding rapidly, driven by its unique formulation for treating agitation in mental health conditions. This article explores its impact.

IGALMI Sees Remarkable Growth in Market Accessibility for Mental Health Treatments #United_States #Las_Vegas #IGALMI #Dexmedetomidine #BioXcel_Therapeutics

Renal ischaemia-reperfusion injury (IRI) is an important cause of #AKI after major surgery. #Dexmedetomidine has demonstrated multimodal renoprotective properties, effectively mitigating against renal #IRI

1/ IJOA at a Glance Series
Evidence for #dexmedetomidine in #ObAnes #ObAnaes
Article link: doi.org/10.1016/j.ij...

New from #BJAOpen: Perioperative use of #dexmedetomidine appears to be safe in patients undergoing orthotopic heart transplantation. #transplant #mortality #openaccess

Check out the latest issue of #BJAOpen.

Free to view articles on: #environmental #sustainability, #transfusion, #intubation, #SGAs, #prehospital, #ERAS, #mRNAs, #dexmedetomidine

PRECEDEX (dexmedetomidine) IV
1) Dose Regimens for ICU Sedation
apps.apple.com/us/app/apoth...
#MedEd #CriticalCare #ICU #Medstudent #medicalstudent #medicine #healthcareIT #healthcare #FOAMcc #USMLE #internalmedicine #sedation #anesthesia #precedex #dexmedetomidine

Nice to be up to the point in a manuscript where supervisor/co-authors have provided significant feedback and are happy and look forward to a polished version in a few weeks... which is lovely, except for future me who gets to hit "accept changes" and wield the axe! #phd #pallmed #dexmedetomidine