IL-12 drives the expression of the inhibitory receptor NKG2A on human tumor-reactive CD8 T cells - Nature Communications Effective strategies to enhance T cell anti-tumor cytotoxicity are pivotal to improve treatment outcomes. By analyzing tumor samples from patients with head and neck or colon cancers, here the authors...

Happy to share my new paper done under the mentorship of Dr. Thomas Duhen at #EACRI, bringing new insights about the role of IL-12 in tumor immunity.
#FinishCancer

www.nature.com/articles/s41...

IL-12 drives the expression of the inhibitory receptor NKG2A on human tumor-reactive CD8 T cells Nature Communications - Effective strategies to enhance T cell anti-tumor cytotoxicity are pivotal to improve treatment outcomes. By analyzing tumor samples from patients with head and neck or...

Underscoring the complexity of #anticancer immunity, Dr Fesneau in the Duhen lab @ #EACRI showed that #IL-12, while driving CD8 T cells to CTL, also drives up-regulation of #immunoregulatory #NKG2A on human #tumor-reactive #CD8.
rdcu.be/d0A7V. Very nice work by a great group #FinishCancer

Comprehensive Genomic Profiling Improves Precision Therapy Use and Patient Survival Two-thirds of patients with advanced cancer whose biopsies were tested using an in-house comprehensive genomic profiling assay were found to be candidates for precision therapies, according to a study...

💥WOW!! Imagine if there was a test #cancer #patients could take that had a 67% chance of changing their #treatment and the potential to increase their #survival? THERE IS! #EACRI #PCI #Illumina @microsoftcopilot.bsky.social #targeted #therapy #immunotherapy

dailynews.ascopubs.org/do/comprehen...

Bernard Fox received SITC lifetime achievement award - OncoDaily Bernard Fox received SITC lifetime achievement award / Bernard Fox, cancer, cancer immunotherapy, Headlines, OncoDaily, Oncology, SITC lifetime achievement

Thanks #OncoDaily for the shout out! As noted, no one does this alone. I was incredibly fortunate to have the very best colleagues/friends, students, fellows, supportive philanthropists, & amazing staff at #EACRI & #SITC to work with & together we strove to #FinishCancer.
oncodaily.com/blog/184007