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Fig. 2. Representative treatment plan of salvage proton (compared with photon) SBRT for locally recurrent PCa. 30 Gy to whole gland + 40 Gy SIB to DIL at base/seminal vesicle junction. (Left) proton plan, (Center) photon plan, (Right) excess bladder, penile and rectal radiation with photons compared to protons.

Fig. 2. Representative treatment plan of salvage proton (compared with photon) SBRT for locally recurrent PCa. 30 Gy to whole gland + 40 Gy SIB to DIL at base/seminal vesicle junction. (Left) proton plan, (Center) photon plan, (Right) excess bladder, penile and rectal radiation with photons compared to protons.

Up to half of #prostatecancer recurrences following #EBRT occur exclusively within the prostate - read a #PTCOG Genitourinary Subcommittee evaluation of the advantages & challenges of PT for radio-recurrent prostate cancer: www.sciencedirect.com/science/arti...

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Modern EBRT reduces CVD risk in breast cancer patients Modern EBRT for breast cancer treatment leads to minimal increases in CVD risk, an improvement over previous EBRT techniques.

Advances in external beam radiation therapy (EBRT) techniques in breast cancer treatment have mitigated cardiovascular disease (CVD) risk in women #radiology #breastcancer #EBRT #CVD

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How is #reirradiation currently used for #breastcancer recurrence?
The Reirradiation Focus Group is gathering insights on #EBRT practices across the community, from patient selection to clinical approaches.
πŸ“ Take the survey: bit.ly/3PLXm3u
πŸ“… Deadline: 8 May 2026

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Île-de-France: Electric bi-articulated buses commence operation on the Tzen 4 BRT line - Urban Transport Magazine In the greater Paris area – the Île-de-France region – the long-awaited new Tzen 4 Bus Rapid Transit line commenced operation on 10 February 2026: it substantially improves mobility in the Essonne dep...

Big electric buses increase capacity and reduce costs for busy #eBRT / eBHNS lines. This could be the next step for the @bctransit.com Blink 95 line from the BC Legislature to Langford? www.urban-transport-magazine.com/en/ile-de-fr... #yyj #bcpoli @bettertransityyj.ca

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Large Language Models Fail to Reproduce Level I Recommendations for Breast Radiotherapy | medRxiv This study evaluates the reliability of the largest public-facing large language models in providing accurate breast cancer radiotherapy recommendations. We assessed ChatGPT 3.5, ChatGPT 4, ChatGPT 4o, Claude 3.5 Sonnet, and ChatGPT o1 in three common clinical scenarios. The clinical cases are as follows: post-lumpectomy radiotherapy in a 40 year old woman, (2) postmastectomy radiation in a 40 year old woman with 4+ lymph nodes, and (3) postmastectomy radiation in an 80 year old woman with early stage tumor and negative axillary dissection. Each case was designed to be unambiguous with respect to the Level I evidence and clinical guideline-supported approach. The evidence-supported radiation treatments are as follows: (1) Whole breast with boost (2) Regional nodal irradiation (3) Omission of post-operative radiotherapy. Each prompt is presented to each LLM multiple times to ensure reproducibility. Results indicate that the free, public-facing models often fail to provide accurate treatment recommendations, particularly when omission of radiotherapy was the correct course of action. Many recommendations suggested by the LLMs increase morbidity and mortality in patients. Models only accessible through paid subscription (ChatGPT o1 and o1-mini) demonstrated greatly improved accuracy. Some prompt-engineering techniques, rewording and chain-of-reasoning, enhanced the accuracy of the LLMs, while true/false questioning significantly worsened results. While public-facing LLMs show potential for medical applications, their current reliability is unsuitable for clinical decision-making. ### Competing Interest Statement The authors have declared no competing interest. ### Funding Statement This study did not receive any funding ### Author Declarations I confirm all relevant ethical guidelines have been followed, and any necessary IRB and/or ethics committee approvals have been obtained. Yes I confirm that all necessary patient/participant consent has been obtained and the appropriate institutional forms have been archived, and that any patient/participant/sample identifiers included were not known to anyone (e.g., hospital staff, patients or participants themselves) outside the research group so cannot be used to identify individuals. Yes I understand that all clinical trials and any other prospective interventional studies must be registered with an ICMJE-approved registry, such as ClinicalTrials.gov. I confirm that any such study reported in the manuscript has been registered and the trial registration ID is provided (note: if posting a prospective study registered retrospectively, please provide a statement in the trial ID field explaining why the study was not registered in advance). Yes I have followed all appropriate research reporting guidelines, such as any relevant EQUATOR Network research reporting checklist(s) and other pertinent material, if applicable. Yes All data produced in the present work are contained in the manuscript

interesting research on using LLMs for guiding #bcsm #BreastCancer #EBRT #radonc decision-making for three types of cases for breast radiotherapy. Not surprised that these "stochastic parrots" don't know what they are spewing out. www.medrxiv.org/content/10.1101/2024.11....

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Some additional accounts added to Isocenter starter pack. Please message / like / repost / reply so I can add you. This is meant to be a general list of professionals of #radonc #ClinOnc #medphys #radther #rmeddosim #brachytherapy #EBRT #IGRT #IMRT #IORT #ProtonRT #SBRT #StereoRT go.bsky.app/9dMTnSr

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Treatment trends:

πŸ“ Local therapies (e.g: #ablation, #EBRT, #resection) stayed stable, with slight drops in #embolization & #transplant.
πŸ“ Systemic therapy shifted to novel options: #lenvatinib, #nivolumab, #atezo/bev, #pembrolizumab.
πŸ“ˆ Median lines of treatment rose from 1.2 to 1.4 (p=0.004).

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