This review details the cleavage functions of major #NucleicAcid #Endonucleases and #Exonucleases, their coordinated roles in #DNADamage, and their impact on #Immune activation in #Autoimmune #diseases and #Tumors. #medsky

#OpenAccess: www.sciencedirect.com/science/arti...

To cleave or not and how? The DNA exonucleases and endonucleases in immunity

This review provides a comprehensive overview on the functions of different exonucleases & #endonucleases, & highlights their roles in #DNADamageRepair, maintaining genome integrity, & regulating the innate immune cGAS-STING pathway. #medsky

#OpenAccess : https://buff.ly/3PTPOZt