This study reveals the synergy between #Lansoprazole & #PARPinhibitors (PARPi) that suppresses BRCA1 expression in TNBC via #FASN inhibition, underscoring the #therapeutic potential of PARPi in #Tumors lacking #BRCA germline #Mutations. #medsky

#OpenAccess: www.sciencedirect.com/science/arti...

📚MedChemExpress Digest | Targeting #Lipid #Metabolism in #Cancer
🔬Cancer cells reprogram lipid uptake, synthesis & oxidation to fuel growth, survive stress & evade immunity. These pathways (#CD36, #FASN, #ACLY, #ACC, #SREBP) offers promising anticancer strategies. 👉Discover more: ow.ly/8RmS50XgbgE

Honored and humbled to be awarded the Fellowship of American Society of Nephrology. Grateful for the support of mentors, colleagues, and the nephrology community. Excited to continue working toward advancing kidney health! #ASN #FASN

The rumours are true - there really are socks for #FASN at member services! Just one more reason to LOVE #KidneyWk ❤️⭐️👏

Worked on a great #FASN inhibitor 5 years ago when I was at #GSK. So glad to see this area flourishing! twitter.com/kapellerrosana/status/79...