m6A RNA methylation #FGF16 #CardiacRegeneration

AAV9-shRNA Mettl3⏫🫀repair in neonate p3 (apex resection), p7 (MI) & 3 mo (MI)

Fgf16 mRNA was destabilized upon m6A (Mettl3-Ythdf2)

AAV9-Fgf16 m6A site mutant (not WT) ⏫neonatal🫀regeneration

@elife.bsky.social 2022
elifesciences.org/articles/77014