Resolving the Interference of Anti‐CD38 Antibodies on Blood Compatibility Assays Using CD38 “Baitbodies” Approach Blood transfusion safety depends on swift blood compatibility testing. Alloantibodies recognizing these blood group antigens determine blood compatibility, and the transfusion of incompatible blood c...

A CD38 "baitbody" to support safe blood products for multiple myeloma patients receiving Daratumumab and Isatuximab.
onlinelibrary.wiley.com/doi/full/10....

#baitbody, #daratumumab, #felzartamab, #isatuximab, #transfusionmedicine, #antibody, #fusionprotein, #bloodcompatability, #CD38, #MM

Calcineurin-binding protein 1 (#CABIN1) directly binds to the #MEF2D #FusionProtein, thereby affecting cell survival and modulating the expression of core regulatory factors of BCP-ALL in the MEF2D::HNRNPUL1 cell lines.

#OpenAccess: doi.org/10.1038/s413...

Dual targeting of RET and SRC synergizes in RET fusion-positive cancer cells

🔦 buff.ly/wj2wwUX

@EmilianoCocco2 #NSCLC #RETfusion #FusionProtein

© Martin Oeggerli (www.Micronaut.ch) 2019-2025, with Marcel Philipp Trefny, and Prof. Alfred Zippelius, Cancer Immunology, University Hospital Basel, Pathology University Hospital Basel, and C-CINA, Biozentrum, University Basel

Researchers @biomedizin.unibas.ch developed cartilage implants from nasal septum cells, and showed that allowing them to mature for two weeks improved outcomes. 🔬Congratulations to all contributors.
doi.org/10.1126/scit...

#Immunotherapy #CancerImmunology #FusionProtein #PD1IL2v #TCellTherapy

Challenges and solutions for the downstream purification of therapeutic proteins Statement of Significance: The diversity of protein structures has led to an increased complexity of product- and process-related impurities. The article s

This review of purification strategy of therapeutic proteins received 23 citations already.

#Downstream #Purification #TherapeuticProtein #mAba #FusionProtein #VHH #scFv
@antibodytx.bsky.social

Fusion protein controls design of #photosynthesis platform - http://www.uni-mainz.de/presse/18298_ENG_HTML.php #fusionprotein #chloroplast http://t.co/1lLikSPZCl