The #GTPase #Npa3 plays a key role in RNA Pol II assembly & nuclear import. In a new study, Martín Mora-García et al. reveal crosstalk between Npa3 and #TORC1 signalling, suggesting involvement in translation initiation, TORC1 signaling, and #stress adaptation🧬

Read it here: tinyurl.com/bdau2mp2

The small #GTPase Rab1 is a master regulator of #Golgi traffic and #autophagy. In @jcb.org, van Vliet, Munro et al. @mrclmb.bsky.social performed a proteomic screen to identify novel Rab1 effectors, including a #dynein motor adaptor and cargo receptors for autophagy. rupress.org/jcb/article/...

The small #GTPase Rab1 is a master regulator of #Golgi traffic and #autophagy. van Vliet, Munro et al. @mrclmb.bsky.social performed a proteomic screen to identify novel Rab1 effectors, including a #dynein motor adaptor and cargo receptors for autophagy. rupress.org/jcb/article/...

#Trafficking

Saito and colleagues show Septin2, a cytoskeletal protein, partners with ARHGAP25 to regulate Rho #GTPase Rac, shaping the actin #Cytoskeleton and controlling cell morphology:

➡️ doi.org/10.1002/1873-3468.70041

Looking for a ImageJ plugin for FRET? Using pixFRET but do other plugins exist? Also, can one do FRET between a GTPAse and its GAP? This is a transient interaction where the GAP dissociates when the GTP hydrolyzes. Can one capture this by FRET? #microscopy #imaging #ImageJ #cellbiology #GTPase

Beautiful imaging on the cover but also check out the beautiful imaging inside and our story on #endosomes and #GTPase cascades

#Microbes like comics, too! #RNA is the language, #extracellularvesicles serve as speech bubbles.
Out now in PNAS by Joshua Mills, Susanne Erdmann et al.

Read more: mpi-bremen.de/en/Microbial...

Full paper: pnas.org/doi/10.1073/...

#archaea #GTPase #EV #evolution