Seeing the current president called “president poopy pants” makes me wince. & yes, I detest him.

If you or someone you love—or hell even like—have ever lost control of your bowels, you get how awful it is. #Incontinence isn’t funny at all. Sorry poo emoji 💩.

#IBS #BowelHealth #GutSky #dignity

A host enzyme reduces metabolic dysfunction-associated steatotic liver disease (MASLD) by inactivating intestinal lipopolysaccharide A MASLD mouse model reveals that gut-derived Gram-negative bacterial lipopolysaccharides promote hepatic lipid accumulation and acyloxyacyl hydrolase, a host lipase that degrades and inactivates lipopolysaccharides and mitigates MASLD.

New @elife.bsky.social paper reveals: AOAH, an enzyme that inactivates gut-derived LPS, protects against fatty liver disease by reducing lipid accumulation and inflammation in the liver. Targeting AOAH could offer a novel therapeutic strategy for MASLD. doi.org/10.7554/eLif... 🧪 #LiverSky #GutSky

Recently posted a blog post I wrote on a tool I use personally for GI flares - a Flare Recovery Plan.

Here's the podcast on what a Flare Recovery Plan is & how to start to make one.

Sharing in case it can be of help...

youtu.be/62PgX_BCCwg?...

#gastrosky #gutsky #GIpsych

How to Get Through a GI Flare | A Plan That Works — Rest & Digest Struggling with a GI flare? Learn how to create a personal Flare Recovery Plan that will help you to know what to do when a digestive symptoms hits. It will help you reduce stress, avoid common mist...

Us familiar with GI psych know GI flares often need more than just meds. I wrote up a tool I use myself, what I call a Flare Recovery Plan.

Sharing in case it can be of help...

www.restanddigest.org/blog/how-to-...

#gastrosky #gutsky

🧠💻 The AGA 2025 Guideline on CADe-assisted colonoscopy makes no recommendation—due to very low certainty in reducing #CRC incidence or mortality.
✅ ADR improve ⚠️ But more low-risk polyp detection → increased surveillance, cost & patient burden. #GiSky #GutSky
www.gastrojournal.org/article/S001...

Efficacy of Linaclotide in Functional Dyspepsia and Constipation-Predominant Irritable Bowel Syndrome Overlap: A Randomized Trial - PubMed ClinicalTrials.gov: NCT05134584.

📚 New Research: Linaclotide outperforms Lactulose for treating Functional Dyspepsia + IBS-C overlap. 🌟
✅ 87.2% of patients on Linaclotide reported symptom relief vs just 54.2% on Lactulose
📈 Bloating, abdominal discomfort, stool frequency
🔬 pubmed.ncbi.nlm.nih.gov/40079184/
#GutSky #IBSSky #DGBI

Breathing to Soothe Digestive Symptoms

A simple guided DB practice for general use of GI conditions

Last episode was focused on pain & urgency and provided more underlying rationale. This one has more space for sinking into the practice

www.restanddigest.org/podcast

#gastrosky #gutsky #ANSsky

"Constipation is a common GI symptom in pure autonomic failure, affecting nearly half of patients. It often shows up alongside other autonomic issues, highlighting the complexity of managing this condition. 🧠🚽 #NeurologySky #GutSky #ANSSky #https://pubmed.ncbi.nlm.nih.gov/40053259/

Ad for virtual seminar by Dr. Kris Sankaran, Assistant Professor, Department of Statistics, University of Wisconsin-Madison, with headshot of individual with dark curly hair and glasses wearing zippered jacket and white shirt. Seminar is via Zoom: contact Cierra.streeter@vumc.org for access.

This week's Wednesday webinar (Feb. 26) at Vanderbilt Biostatistics is "Topic Models in Microbiome Analysis," at 1:30 pm CT, by Kris Sankaran @sankaranlab.bsky.social www.vumc.org/biostatistic... #RStats #GISky #GutSky #MedSky #TopicModeling

🔥New study: Psychological stress can break oral tolerance to food, triggering IgE-mediated mast cell activation & gut pain hypersensitivity—offering insights into stress-induced IBS. #GISky #GutSky #DGBI #MedSky
📃els-jbs-prod-cdn.jbs.elsevierhealth.com/article/S0016-5085(25)00...

First meeting of the APAGE Emerging Leader Committee DGBI Special Interest Group! Discussing initiatives for 2025 and beyond. Stay tuned for updates! #GiSky #GutSky

Can't wait to reconnect with old friends at #DDW2025! 📷 So many events, so little time! See you all in 77 days and 4 hours! 📷📷 #BeGutsy #gicommunity #ddw2025 #DGBI #GISky #GutSky

New study shows an IgG-based elimination diet improved #IBS symptoms in 59.6% of patients vs 42.1% on a sham diet (n=223). Interesting, but subgroup analysis suggests it may work better for IBS-C and IBS-M than IBS-D. #GISky #GutSky #DGBI pubmed.ncbi.nlm.nih.gov/39894284/

Harvard Scientists Uncover How Gut Bacteria Fuel Inflammation and Depression Harvard researchers have found that M. morganii may contribute to depression by producing an inflammatory molecule. Biochemical analyses reveal how the gut bacterium Morganella morganii may contribute...

Interesting study linking an environmental contaminant to depression via a gut microbe, although the really new thing for me was that IL-6 promotes depression? #ImmunoSky #Neurosky #MicroSky #GutSky #microbiomeSky
scitechdaily.com/harvard-scie...

Advanced #Parkinson’s led to severe colonic dysmotility, fecal impaction, & kidney issues in a 77-yr-old. Treated with rectal tube + meds, but no cure for alpha-synuclein damage. 🚨 Early recognition key! #stoolcankill 🧠💩 #GISky #GutSky #constipation #DGBI #FGID pubmed.ncbi.nlm.nih.gov/39917098/

#Stoolcankill: Rare case of ileal fecaloma causing small bowel obstruction in a 60yo 🧓with chronic #constipation. Surgical intervention successfully resolved the obstruction. Highlights importance of considering fecaloma in SBO differentials. #GiSky #Gutsky #DGBI pubmed.ncbi.nlm.nih.gov/39905511/

Digital eHealth vs onsite 2-day IBS education: Digital program significantly ⬇️ symptom severity in 41% of pts & improved QoL, anxiety, depression. Both interventions scored high on client satisfaction. eHealth is a viable, for IBS self-management. #GutSky #GISky humanfactors.jmir.org/2025/1/e43618

#Gastroparesis Dx requires Sx like nausea/vomiting; asymptomatic cases excluded. N&V are key; bloating, pain less linked to severity. Overlaps with #FDyspepsia, but distinct patterns. QoL, mental health impacted. Weight loss not always present. #GutSky #GISky www.thelancet.com/journals/lan...

🚨 New @AmerGastroAssn update! 🚨 Screening & surveillance are key for #gastric cancer prevention in high-risk U.S. groups. Endoscopy + H. pylori eradication = crucial steps. Personalized risk-based approach needed. 🔗 doi.org/10.1053/j.ga... #GISky #medsky #GutSky

Specialty laboratory testing for chronic abdominal pain in irritable bowel syndrome - PubMed The findings emphasize the effectiveness and importance of adhering to Rome IV criteria, as advanced testing often fails to improve diagnostic accuracy and increases unnecessary healthcare costs.

🔍 Overtesting in IBS? A study of 26,732 IBS patients found that 85.3% of advanced serologic tests were ordered by GIs, yet only 12.5% followed guidelines, with a mere 2.1% positive rate. 💰 $39K wasted on unnecessary tests. Stick to Rome IV criteria! #GISky #GutSky
pubmed.ncbi.nlm.nih.gov/39853154/

🌟 Recognizing #DGBI in patients with organic GI disease remission prevents overtreatment with risky drugs and ensures targeted care. Let’s focus on better outcomes! 👉 bit.ly/3Ee3iwv #GISky #MedSky #GutSky

New insights from the Rome Foundation Report:

DGBI overlaps across GI & non-GI regions suggest a spectrum of disorders.
Persistent symptoms in organic GI disease remission need careful diagnosis.
Multidisciplinary care + gut-brain axis therapies = the future. #GISky #GutSky #DGBI

Excited share that our @romefoundation.bsky.social Working Team's manuscript 📄 on Overlap in Disorders of Gut-Brain Interaction #DGBI is now published in @natrevgastrohep.bsky.social! Grateful for this amazing journey with global experts. Read here: nature.com/articles/s41...
#DGBI #GISky #GutSky

New meta-analysis highlights acupuncture's potential for IBS-D patients—relieving symptoms, anxiety, and depression while boosting response rates. Promising steps forward for the gut-brain connection! 🌱🧠 #IBS #GutHealth #MentalHealth dx.doi.org/10.1097/MD.0... #GISky #GutSky #Medsky #DGBI #FGID

I’ve been on Bluesky for a bit and felt we needed a space to bring the DGBI community together. So, I created the #DGBI Starter Pack! A place to connect, share ideas, and grow as a network. Join in and let’s make gut health the focus! #GISky #GutSKy #IBS 🌟➡️https://go.bsky.app/5PZzEvd

I've been on Bluesky for a while now, waiting for a starter pack to bring the #DGBI community together. Since none existed, I decided to create one myself! The DGBI Starter Pack is here to help us connect, share, and grow together. Join us and make gut health a priority! 🌐🌱 #GISky #GutSky #IBS #FGID

"How does colonoscopy impact gut microbiota? 🦠 New insights on changes, mechanisms, and probiotics for recovery in Clinical Endoscopy (2025). Highly recommended 🤓 ! 📖 doi.org/10.5946/ce.2... #GutSky #GISky #Microbiota

Brilliant work by Christopher J. Black and Alexander on #IBS! 🌟 Comprehensive insights into diagnosis, dietary approaches, pharmacology, and gut-brain therapies. A must-read for anyone in #GIHealth #GutSky #GISky #DGBI pubmed.ncbi.nlm.nih.gov/39835671/

Autoimmune Pancreatitis: 🌟

From its classification into types 1 & 2 to cutting-edge treatments like glucocorticoids & B-cell depletion therapies, new insights redefine AIP care.

Dive into this UEG review . 🔗 doi.org/10.1002/ueg2... #GIHealth #AutoimmunePancreatitis #GISky #GutSky

Is Lubiprostone still available in your country? 🤔 Lubiprostone shows efficacy in managing chronic idiopathic constipation, IBS-C, and opioid-induced constipation. This meta-analysis highlights improved bowel movements & quality of life. #Gutsky #GIsky #Gastrosky #DGBI doi.org/10.1002/jgh3...