This week, we discuss a study from the lab of Dr. Trista North (@tristanorth.bsky.social!
It shows that #HSPCs expand while staying multipotent thanks to tightly controlled ROS levels regulated by developmental #mitophagy.
๐ https://go.nature.com/4tWuJ3e
๐ง https://bit.ly/46XtIy5
Hashtag
#HSPCs
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Happy #FluorescentFriday (last for 2024)! Visualizing hematopoietic stem and progenitor cells (HSPCs; runx1:cherry; cd41:GFP) in the zebrafish ventricle! A glimpse into the intricate choreography of stem cell biology. ๐งฌ๐ก #Zebrafish #HSPCs #StemCells
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From Sept '24: Signals arising from innate RNA-sensing pathways prevent hematopoietic stem and progenitor cells from being engulfed by macrophages, helping to promote clonal diversity in adult zebrafish.
https://buff.ly/4ffwK23
#HSPCs @science.org
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