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Advertisement ยท 728 ร— 90
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This week, we discuss a study from the lab of Dr. Trista North (@tristanorth.bsky.social!

It shows that #HSPCs expand while staying multipotent thanks to tightly controlled ROS levels regulated by developmental #mitophagy.

๐Ÿ“„ https://go.nature.com/4tWuJ3e
๐ŸŽง https://bit.ly/46XtIy5

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Happy #FluorescentFriday (last for 2024)! Visualizing hematopoietic stem and progenitor cells (HSPCs; runx1:cherry; cd41:GFP) in the zebrafish ventricle! A glimpse into the intricate choreography of stem cell biology. ๐Ÿงฌ๐Ÿ’ก #Zebrafish #HSPCs #StemCells

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From Sept '24: Signals arising from innate RNA-sensing pathways prevent hematopoietic stem and progenitor cells from being engulfed by macrophages, helping to promote clonal diversity in adult zebrafish.

https://buff.ly/4ffwK23

#HSPCs @science.org

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